CAS 5534-09-8: Dipropionato de beclometasona
Descripción:
Dipropionato de beclometasona es un corticosteroide sintético con propiedades antiinflamatorias e inmunosupresoras, utilizado principalmente en el tratamiento de condiciones respiratorias como el asma y la rinitis alérgica. Se caracteriza por su capacidad para reducir la inflamación y aliviar los síntomas asociados con estas condiciones. La sustancia se administra típicamente por inhalación o como un aerosol nasal, permitiendo una acción localizada con una mínima absorción sistémica. Químicamente, es un derivado de beclometasona, que presenta dos grupos de éster propionato que mejoran su lipofilia y potencia. Dipropionato de beclometasona exhibe una alta afinidad por los receptores de glucocorticoides, lo que lleva a la modulación de la expresión génica involucrada en las respuestas inflamatorias. Su farmacocinética indica un inicio de acción rápido, aunque los efectos terapéuticos completos pueden tardar varios días en manifestarse. Los efectos secundarios comunes pueden incluir irritación local o disfonía, pero los efectos sistémicos generalmente se minimizan debido a su entrega dirigida. En general, Dipropionato de beclometasona es un agente eficaz en el manejo de condiciones inflamatorias crónicas de las vías respiratorias.
Fórmula:C28H37ClO7
InChI:InChI=1S/C28H37ClO7/c1-6-23(33)35-15-22(32)28(36-24(34)7-2)16(3)12-20-19-9-8-17-13-18(30)10-11-25(17,4)27(19,29)21(31)14-26(20,28)5/h10-11,13,16,19-21,31H,6-9,12,14-15H2,1-5H3/t16-,19-,20-,21-,25-,26-,27-,28-/m0/s1
Clave InChI:InChIKey=KUVIULQEHSCUHY-XYWKZLDCSA-N
SMILES:C(COC(CC)=O)(=O)[C@]1(OC(CC)=O)[C@]2(C)[C@@](C[C@@H]1C)([C@]3([C@](Cl)([C@@H](O)C2)[C@]4(C)C(CC3)=CC(=O)C=C4)[H])[H]
Sinónimos:- (11Beta,16Beta)-9-Chloro-11-Hydroxy-16-Methyl-3,20-Dioxopregna-1,4-Diene-17,21-Diyl Dipropanoate
- (11β,16β)-9-Chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione
- (9Z,11E,13Z)-octadeca-9,11,13-trienoic acid
- 17,21-Dipropionate De 9-Chloro-11Β-Hydroxy-16Β-Methylpregna-1,4-Diene-3,20-Dione
- 17,21-Dipropionato De 9-Cloro-11Β-Hidroxi-16Β-Metilpregna-1,4-Dieno-3,20-Diona
- 9-Chlor-11β-hydroxy-16β-methylpregna-1,4-dien-3,20-dion-17,21-dipropionat
- 9-Chloro-11Β-Hydroxy-16Β-Methylpregna-1,4-Diene-3,20-Dione 17,21-Dipropionate
- 9α-Chloro-16β-methylprednisolone 17,21-dipropionate
- Aerobec
- Aldecin
- Aldecin AQ nasal
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Beclometasone dipropionate for system suitability CRS
CAS:Beclometasone dipropionate for system suitability CRSFórmula:C28H37ClO7Forma y color:White. Powder.Peso molecular:521.0422Beclometasone dipropionate for peak identification CRS
CAS:Beclometasone dipropionate for peak identification CRSFórmula:C28H37ClO7Peso molecular:521.0422Beclometasone dipropionate monohydrate CRS
CAS:Beclometasone dipropionate monohydrate CRSFórmula:C28H37ClO7Forma y color:White. Powder.Peso molecular:521.0422BECLOMETASONE DIPROPIONATE ANHYDROUS CRS
CAS:BECLOMETASONE DIPROPIONATE ANHYDROUS CRSFórmula:C28H37ClO7Forma y color:Crystalline Powder. White. Powder.Peso molecular:521.0422Beclomethasone dipropionate, 97%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C28H37ClO7Pureza:97%Forma y color:White to off-white, Crystalline powderPeso molecular:521.05Beclomethasone Dipropionate
CAS:Halogenated derivatives of adrenal cortical hormonesFórmula:C28H37ClO7Forma y color:White Cream PowderPeso molecular:520.22278Beclometasone dipropionate
CAS:Beclometasone dipropionateFórmula:C28H37ClO7Pureza:99.4%Forma y color:WhitePeso molecular:520.22278Beclometasone (Beclomethasone) Dipropionate (Betamethasone Dipropionate EP Impurity E)
CAS:Fórmula:C28H37ClO7Forma y color:White To Off-White SolidPeso molecular:521.06Beclometasone dipropionate
CAS:Beclometasone dipropionate (Vancenase) is the dipropionate ester of a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Fórmula:C28H37ClO7Pureza:98% - 98.49%Forma y color:SolidPeso molecular:521.04Beclometasone dipropionate
CAS:Producto controladoFórmula:C28H37ClO7Forma y color:NeatPeso molecular:521.04Beclometasone Dipropionate
CAS:Producto controladoFórmula:C28H37ClO7Forma y color:NeatPeso molecular:521.04Beclomethasone dipropionate
CAS:Producto controladoBeclomethasone dipropionate is a synthetic corticosteroid, which is derived from beclomethasone, a glucocorticoid steroid. Its mode of action involves binding to specific intracellular glucocorticoid receptors. This binding modulates the transcription of glucocorticoid-responsive genes, leading to the synthesis of anti-inflammatory proteins and the inhibition of pro-inflammatory cytokine production. This reduces airway inflammation, edema, and mucus production, and enhances the responsiveness of beta-adrenergic receptors in the bronchial smooth muscle, facilitating bronchodilation. Beclomethasone dipropionate is primarily used in the management and prevention of asthma and allergic rhinitis. Its anti-inflammatory properties are crucial in controlling chronic asthma symptoms, reducing the frequency and severity of asthmatic episodes, and minimizing the need for systemic corticosteroids. Additionally, it can be used in treating chronic obstructive pulmonary disease (COPD) as part of combination therapy. Administered via inhalation, it ensures targeted action in the respiratory tract, minimizing systemic absorption and thereby reducing potential side effects associated with oral corticosteroid therapy.Fórmula:C28H37ClO7Pureza:Min. 95%Forma y color:PowderPeso molecular:521.04 g/molBeclomethasone Dipropionate-d10
CAS:Producto controladoApplications Antiallergic, antiasthmatic(inhalate). Anti-inflammatory(topical). References Laube, B., et al.: J. Allergy Clin. Immunol., 101, 475 (1998), Harrison, L., et al.: Eur. J. Clin. Pharmacol., 58, 191 (2002) , Maneechotesuwan, K., et al.: J. Allergy Clin. Immunol., 121, 43 (2008).Fórmula:C28D10H27ClO7Forma y color:NeatPeso molecular:531.10Beclometasone dipropionate
CAS:Fórmula:C28H37ClO7Pureza:98.0 - 102.0 % (dried basis)Forma y color:White to almost white powderPeso molecular:521.04GB/T 24800.2-2009 41 Glucocorticoids 100 µg/mL in Methanol
CAS:Producto controlado- 105102-22-5
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Forma y color:MixtureBeclometasone dipropionate, EP grade
CAS:Fórmula:C28H37ClO7Pureza:≤ 0.1%Forma y color:White to almost white crystalline powderPeso molecular:521.04Beclometasone Dipropionate
CAS:Fórmula:C28H37ClO7Pureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:521.05
