CAS 59-48-3: Oxindol
Descripción:
Oxindol es un compuesto orgánico caracterizado por su estructura bicíclica, que consiste en un anillo de indol fusionado a un grupo carbonilo. Es un sólido cristalino blanco a blanco sucio que es soluble en disolventes orgánicos como el etanol y el cloroformo, pero tiene una solubilidad limitada en agua. La fórmula molecular de Oxindol es C8H7NO, y presenta un átomo de nitrógeno dentro del marco del indol, lo que contribuye a sus propiedades básicas. Oxindol es conocido por su papel en diversas actividades biológicas, incluidas aplicaciones potenciales en farmacéuticos, donde sirve como un andamiaje para el desarrollo de medicamentos dirigidos a trastornos neurológicos y otras condiciones. Además, puede participar en diversas reacciones químicas, como sustituciones electrofílicas y ciclizaciones, lo que lo convierte en un intermediario valioso en la síntesis orgánica. Sus derivados han sido estudiados por sus propiedades antiinflamatorias, analgésicas y antitumorales, destacando la importancia del compuesto en la química medicinal. En general, Oxindol es un compuesto versátil con importantes implicaciones tanto en la investigación como en la industria.
Fórmula:C8H7NO
InChI:InChI=1S/C8H7NO/c10-8-5-6-3-1-2-4-7(6)9-8/h1-4H,5H2,(H,9,10)
Clave InChI:InChIKey=JYGFTBXVXVMTGB-UHFFFAOYSA-N
SMILES:O=C1CC=2C(N1)=CC=CC2
Sinónimos:- 1,3-Dihydroindol-2-one
- 1,3-dihydro-2H-indol-2-one
- 2,3-Dihidroindol-2-Ona
- 2,3-Dihydro-1H-indol-2-one
- 2,3-Dihydroindol-2-One
- 2,3-Dihydroindol-2-on
- 2,3-Dihydroindole-2-One
- 2-Indolinone
- 2-Indolone
- 2-Oxindole
- 2-Oxo-2,3-dihydroindole
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Encontrado 19 productos.
Oxindole
CAS:Oxindole (Indolin-2-one) is an aromatic heterocyclic building block.Fórmula:C8H7NOPureza:97.42% - 99.34%Forma y color:Off-White Crystalline PowderPeso molecular:133.152-Oxindole
CAS:2-OxindoleFórmula:C8H7NOPureza:By gc: 99.7% by area (Typical Value in Batch COA)Forma y color: light orange powderPeso molecular:133.15g/molOxindole, 97+%
CAS:Oxindole is considered as indole analogue, which shows pharmacological activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C8H7NOPureza:97+%Forma y color:White to dark cream to cream to brown, PowderPeso molecular:133.152-Indolone
CAS:2-Indolone is a synthetic compound that belongs to the class of heterocyclic compounds. It is a trifluoroacetic acid derivative that has been shown to have potent antitumor activity, and it also inhibits cell proliferation. 2-Indolone has been shown to be an effective treatment for inflammatory diseases such as rheumatoid arthritis and Crohn's disease. This compound has been shown to bind to response elements in the promoter region of genes in the basic fibroblast line, and this binding leads to increased expression of gene products involved in inflammation and tumor suppression. The reaction mechanism for 2-indolone involves a two-step process, with activation energies for both steps being high. The first step involves protonation of the C2 hydroxyl group by trifluoroacetic acid, which leads to its displacement by hydrogen from water molecule H2O. In the second step, the oxindole ring opens up, with displacement ofFórmula:C8H7NOPureza:Min. 95%Forma y color:PowderPeso molecular:133.15 g/molOxindole
CAS:Fórmula:C8H7NOPureza:>98.0%(GC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:133.15Oxindole, 97%, pure
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C8H7NOPureza:97%Forma y color:Beige to yellow to orange to pink-brown, PowderPeso molecular:133.15Oxindole
CAS:Fórmula:C8H7NOPureza:(HPLC) ≥ 97.0%Forma y color:White to light yellow or light orange crystalline powderPeso molecular:133.151,3-Dihydro-2H-indol-2-one
CAS:Pureza:97.0%Forma y color:Solid, Chunks or Crystalline PowderPeso molecular:133.14999389648438Oxindole
CAS:Oxindole (Indolin-2-one) is an aromatic heterocyclic building block. 2-indolinone derivatives have become lead compounds in the research of kinase inhibitors.Oxindole structure has been used in receptor tyrosine kinases (RTKs) inhibitors such as SU4984 and intedanib, the RTK family represents an important therapeutic target for anti-cancer drug development.Fórmula:C8H7NOPureza:99.34%Forma y color:Off-White Crystalline PowderPeso molecular:133.15Oxindole
CAS:Lactams, nesoiFórmula:C8H7NOForma y color:White Crystalline PowderPeso molecular:133.05276Oxindole (2-Indolone)
CAS:Producto controladoApplications Indole analogue; shows pharmacological activity. References Mohammadi, M., et al.: Science, 276, 955 (1997), Bramson, H., et al.: J. Med. Chem., 44, 4339 (2001), Lane, M., et al.: Cancer Res., 61, 6170 (2001), Yu, B., et al.: Biochem. Pharmacol., 64, 1091 (2002),Fórmula:C8H7NOForma y color:Light RedPeso molecular:133.15
