CAS 61477-96-1: Piperacilina
Descripción:
Piperacilina es un antibiótico penicilínico semisintético que se utiliza principalmente para tratar una variedad de infecciones bacterianas. Es eficaz contra un amplio espectro de bacterias grampositivas y gramnegativas, incluyendo Pseudomonas aeruginosa. Piperacilina actúa inhibiendo la síntesis de la pared celular bacteriana, lo que lleva a la lisis celular y a la muerte. El compuesto se administra típicamente por inyección, ya que no se absorbe bien cuando se toma por vía oral. Su estructura química incluye un anillo beta-lactámico, que es característico de las penicilinas, y una cadena lateral que mejora su actividad contra ciertas bacterias resistentes. Piperacilina a menudo se combina con un inhibidor de beta-lactamasa, como el tazobactam, para extender su eficacia contra organismos productores de beta-lactamasa. Los efectos secundarios comunes pueden incluir reacciones alérgicas, trastornos gastrointestinales y posibles impactos en la función renal. Debido a su actividad de amplio espectro, Piperacilina se utiliza con frecuencia en entornos hospitalarios para infecciones graves, particularmente en pacientes inmunocomprometidos.
Fórmula:C23H27N5O7S
InChI:InChI=1S/C23H27N5O7S/c1-4-26-10-11-27(19(32)18(26)31)22(35)25-13(12-8-6-5-7-9-12)16(29)24-14-17(30)28-15(21(33)34)23(2,3)36-20(14)28/h5-9,13-15,20H,4,10-11H2,1-3H3,(H,24,29)(H,25,35)(H,33,34)/t13-,14-,15+,20-/m1/s1
Clave InChI:InChIKey=IVBHGBMCVLDMKU-GXNBUGAJSA-N
SMILES:N(C([C@H](NC(=O)N1C(=O)C(=O)N(CC)CC1)C2=CC=CC=C2)=O)[C@H]3[C@@]4(N([C@@H](C(O)=O)C(C)(C)S4)C3=O)[H]
Sinónimos:- (2S,5R,6R)-6-[[(2R)-2-[[(4-Ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
- 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, [2S-[2α,5α,6β(S*)]]-
- Pipracil
- [2S-[2α,5α,6β(S*)]]-6-[[[[(4-Ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptan-2-carbonsaure
- [2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxopiperazin-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
- acide [2S-[2α,5α,6β(S*)]]-6-[[[[(4-ethyl-2,3-dioxopiperazine-1-yl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylique
- acido [2S-[2α,5α,6β(S*)]]-6-[[[[(4-etil-2,3-dioxopiperazin-1-il)carbonil]amino]fenilacetil]amino]-3,3-dimetil-7-oxo-4-tia-1-azabiciclo[3.2.0]heptano-2-carboxilico
- Piperacillin
Ordenar por
Encontrado 19 productos.
Piperacillin
CAS:Producto controladoApplications Broad spectrum semi-synthetic antibiotic related to Penicillin. Antibacterial. References Takai, A., et al.: Chemotherapy, 25, 816 (1977); Bodey, G.P., et al.: Antimicrob. Agents Chemother., 14, 78 (1978); Kuck, N.A., et al.: J. Antibiot., 31, 1175 (1978);Fórmula:C23H27N5O7SForma y color:WhitePeso molecular:517.55piperacillin
CAS:Piperacillin (Pipercillin) is a semisynthetic penicillin with wide spectrum of antimicrobial activity(particularly pseudomonas strains)Fórmula:C23H27N5O7SPureza:98.32% - 98.51%Forma y color:SolidPeso molecular:517.55Piperacillin Sodium Salt
CAS:Fórmula:C23H26N5NaO7SPureza:>98.0%(N)Forma y color:White to Almost white powder to crystalPeso molecular:539.544-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
CAS:Fórmula:C23H27N5O7SPureza:98%Forma y color:SolidPeso molecular:517.5548Piperacillin-d5
CAS:Producto controladoFórmula:C232H5H22N5O7SForma y color:Off-WhitePeso molecular:522.59Piperacillin-d5
CAS:Piperacillin-d5 is a stable isotopically labeled antibiotic, which is synthesized chemically to incorporate deuterium atoms. It is derived from the β-lactam group of antibiotics, sharing properties with its non-labeled counterpart, piperacillin. The incorporation of five deuterium atoms allows researchers to use it as a tracer in various pharmacokinetic and metabolic studies without altering its biological activity. Piperacillin-d5 functions as an inhibitor of bacterial cell wall synthesis. It targets penicillin-binding proteins (PBPs) in susceptible bacteria, impeding the transpeptidation process crucial for peptidoglycan cross-linking. This leads to cell lysis and the ultimate death of the bacterium. The isotopic labeling with deuterium enables precise tracking of the compound in experimental settings by using mass spectrometry techniques. This compound is primarily used in scientific research focused on the metabolism, distribution, and excretion of β-lactam antibiotics. It allows researchers to gain insights into the pharmacokinetics of piperacillin without interference from endogenous substances, providing crucial data for the development of new therapeutic strategies and for understanding drug interactions and resistance mechanisms.Fórmula:C23H22D5N5O7SPureza:Min. 95%Peso molecular:522.59 g/molPiperacillin
CAS:Piperacillin is a β-lactam antibiotic that inhibits the synthesis of bacterial cell walls by binding to penicillin-binding proteins. It is used for the treatment of serious infections caused by gram-negative organisms such as Aerogenes, Enterobacter, and Klebsiella. Piperacillin has a high MIC90 value against Staphylococcus and other gram-positive bacteria, but it is not active against β-lactamase producing strains of bacteria such as E. coli or Klebsiella pneumoniae. The MIC90 values are determined through an analytical method on different strains of bacteria and validated with a sample preparation before use in clinical trials.Fórmula:C23H27N5O7SPureza:Min. 95 Area-%Forma y color:White PowderPeso molecular:517.56 g/molPiperacillin, 95%
CAS:A semisynthetic penicillin with wide spectrum of antimicrobial activity, particularly pseudomonas strains. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C23H26N5NaO7SPureza:95%Forma y color:Powder or crystals or crystalline powder, WhitePeso molecular:539.54PharmaVetResiMix 6 Betalactams-v23 0.2-2.5 µg/mL in Water:Acetonitrile
CAS:- 10206-21-0
- 104557-24-6
- 113-98-4
- 118443-89-3
- 132-98-9
- 13412-64-1
- 1385046-35-4
- 23325-78-2
- 24356-60-3
- 27164-46-1
- 50370-12-2
- 56238-63-2
- 61336-70-7
- 61477-96-1
- 62893-20-3
- 63358-49-6
- 68373-14-8
- 7081-44-9
- 7177-48-2
- 7240-38-2
- 80370-57-6
- 89786-04-9
- 985-16-0
Forma y color:MixturePiperacillin-d5 (N-ethyl-d5)
CAS:Fórmula:C23H22D5N5O7SForma y color:White To Off-White SolidPeso molecular:522.59
![4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,6-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)ca…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00IAVJ.jpg&w=3840&q=75)
