CAS 62893-20-3: Cefoperazona sódica
Descripción:
Cefoperazona sódica es un antibiótico cefalosporínico de amplio espectro, clasificado bajo la tercera generación de cefalosporinas. Se utiliza principalmente para tratar una variedad de infecciones bacterianas, particularmente aquellas causadas por bacterias Gram-negativas, incluyendo Pseudomonas aeruginosa. El compuesto se caracteriza por su estabilidad contra ciertas beta-lactamasas, lo que mejora su eficacia contra cepas resistentes. Cefoperazona sódica se administra típicamente por vía intravenosa o intramuscular debido a su baja biodisponibilidad oral. Es soluble en agua, lo que facilita su uso en entornos clínicos. El fármaco actúa inhibiendo la síntesis de la pared celular bacteriana, lo que lleva a la lisis celular y a la muerte. Los efectos secundarios comunes pueden incluir trastornos gastrointestinales, reacciones alérgicas y alteraciones en la coagulación sanguínea. Al igual que con otros antibióticos, es esencial usar Cefoperazona sódica de manera juiciosa para minimizar el desarrollo de resistencia a los antibióticos. Su farmacocinética implica distribución a través de los tejidos y fluidos del cuerpo, siendo la excreción renal una ruta significativa para la eliminación. En general, Cefoperazona sódica es un agente terapéutico valioso en el manejo de infecciones graves.
Fórmula:C25H27N9O8S2·Na
InChI:InChI=1S/C25H27N9O8S2.Na/c1-3-32-8-9-33(21(39)20(32)38)24(42)27-15(12-4-6-14(35)7-5-12)18(36)26-16-19(37)34-17(23(40)41)13(10-43-22(16)34)11-44-25-28-29-30-31(25)2;/h4-7,15-16,22,35H,3,8-11H2,1-2H3,(H,26,36)(H,27,42)(H,40,41);/t15-,16-,22-;/m1./s1
Clave InChI:InChIKey=NMANBWFYJSWTBZ-WERGMSTESA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](NC([C@H](NC(=O)N3C(=O)C(=O)N(CC)CC3)C4=CC=C(O)C=C4)=O)C2=O)(SCC1CSC=5N(C)N=NN5)[H].[Na]
Sinónimos:- (6R-(6Alpha,7Beta(R*)))-7-(((((4-Ethyl-2,3-Dioxo-1-Piperazinyl)Carbonyl)Amino)(4-Hydroxyphenyl)Acetyl)Amino)-3-(((1-Methyl-1H-Tetrazol-5-Yl)Thio)Methyl)-8-Oxo-5-Thia-1-Azabicyclo(4.2.0)Oct-2-Ene-2-Carboxylic Acid Sodium Salt
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino]-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, sodium salt (1:1), (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, (6R,7R)-
- 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[[[(4-ethyl-2,3-dioxo-1-piperazinyl)carbonyl]amino](4-hydroxyphenyl)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, monosodium salt, [6R-[6α,7β(R*)]]-
- Bioperazone
- Cefazone
- Cefobine
- Cefobis
- Cefogram
- Cefomycin
- Cefoneg
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Encontrado 17 productos.
Cefoperazone sodium salt
CAS:For studying the expression, binding, and inhibition of penicillin-binding proteins.Cefoperazone sodium salt is used in the study of drug-protein binding, expression and inhibition of penicillin-binding proteins during cell wall synthesis. It is as an antibacterial and antimicrobial agent useful for prevention of postoperative infection. It is used as an inhibitor of inactivation of alfa-antitrypsin. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C25H26N9NaO8S2Forma y color:White to pale cream, Crystalline powderPeso molecular:667.65Cefoperazone sodium
CAS:Cefoperazone sodium is a broad-spectrum antibiotic that inhibits bacterial growth by binding to the enzyme topoisomerase IV. It is active against gram-positive bacteria, such as Staphylococcus aureus, and gram-negative bacteria, such as Escherichia coli. This drug also binds to the IL-2 receptor and has shown antibacterial efficacy in a model system. The optimum concentration of cefoperazone sodium is 0.3 mg/mL. Cefoperazone sodium should not be used in combination with sulbactam or other beta lactams because it can cause rapid degradation of these drugs, leading to reduced therapeutic efficacy.Fórmula:C25H26N9NaO8S2Pureza:Min. 95%Forma y color:PowderPeso molecular:667.65 g/molCefoperazone sodium 100 µg/mL in Acetonitrile:Water
CAS:Producto controladoFórmula:C25H26N9O8S2·NaForma y color:Single SolutionPeso molecular:667.65Cefoperazone sodium salt
CAS:Cefoperazone sodium saltFórmula:C25H26N9O8S2·NaForma y color: white to pale buff crystalline powderPeso molecular:667.65g/molCefoperazone sodium salt
CAS:Fórmula:C25H26N9NaO8S2Pureza:870 - 1015 μg/mg (Cefoperazone, anhydrous basis)Forma y color:White to off-white powderPeso molecular:667.65Cefoperazone Sodium Salt
CAS:Producto controladoFórmula:C25H26N9O8S2·NaForma y color:Off-WhitePeso molecular:667.65Cefoperazone sodium salt
CAS:Cefoperazone sodium salt (CP 52640-2) is broad-spectrum cephalosporin with a tetrazolyl moiety, used to treat Pseudomonas infections.Fórmula:C25H26N9NaO8S2Pureza:99.55%Forma y color:Faint Beige PowderPeso molecular:667.65PharmaVetResiMix 6 Betalactams-v23 0.2-2.5 µg/mL in Water:Acetonitrile
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Forma y color:MixtureCefoperazone
CAS:Fórmula:C25H27N9O8S2Pureza:>98.0%(T)(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:645.67Cefoperazone sodium
CAS:Producto controladoFórmula:C25H26N9O8S2·NaForma y color:NeatPeso molecular:667.65Cefoperazone Sodium (CFZ, Cefaperazone Sodium)
CAS:Fórmula:C25H26N9NaO8S2Forma y color:White to slightly yellow, Powder, ClearPeso molecular:667.65Cefoperazone Sodium, USP, Antibacterial.
CAS:Fórmula:C25H26N9NaO8S2Pureza:98%Forma y color:SolidPeso molecular:667.6492Cefoperazone sodium salt, USP grade
CAS:Fórmula:C25H26N9NaO8S2Forma y color:White to faint yellow powder or crystalPeso molecular:667.65
