CAS 635728-49-3: Ethanolato de Darunavir
Descripción:
Ethanolato de Darunavir es un medicamento antirretroviral utilizado principalmente en el tratamiento de la infección por VIH. Pertenece a la clase de inhibidores de la proteasa y es conocido por su capacidad para inhibir la enzima proteasa del VIH-1, que es crucial para la replicación viral. La sustancia se caracteriza por su alta potencia contra diversas cepas de VIH, incluidas aquellas resistentes a otros agentes antirretrovirales. Ethanolato de Darunavir se administra típicamente en combinación con otros medicamentos antirretrovirales para mejorar su eficacia y reducir el riesgo de desarrollo de resistencia. El compuesto es un polvo cristalino blanco a blanco amarillento, soluble en disolventes orgánicos, y tiene una solubilidad relativamente baja en agua, lo que puede afectar su biodisponibilidad. Su perfil farmacocinético incluye una larga vida media, lo que permite una dosificación una vez al día en muchos regímenes de tratamiento. Al igual que con cualquier medicamento, Ethanolato de Darunavir puede tener efectos secundarios, incluidos trastornos gastrointestinales y posibles elevaciones de las enzimas hepáticas, lo que requiere monitoreo durante el tratamiento. En general, desempeña un papel significativo en la terapia moderna del VIH, contribuyendo a mejorar los resultados de los pacientes.
Fórmula:C27H37N3O7SC2H6O
Sinónimos:- Prezista
- Unii-33O78Xf0Bw
- Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3R,3aS,6aR)-hexahydrofuro(2,3-b)furan-3-yl ester, compd. with ethanol (1:1)
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Encontrado 14 productos.
Darunavir Ethanolate
CAS:Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.Fórmula:C29H43N3O8SPureza:99.84%Forma y color:SolidPeso molecular:593.74Ref: TM-T3335
5mg37,00€10mg52,00€25mg80,00€50mg111,00€100mg165,00€200mg236,00€500mg399,00€1mL*10mM (DMSO)48,00€Darunavir Ethanolate
CAS:Sulfonamides used as drugsFórmula:C27H37N3O7S·C2H6OForma y color:White Beige PowderPeso molecular:593.27709(3R,3As,6Ar)-Hexahydrofuro[2,3-B]Furan-3-Yl ((2S,3R)-4-(4-Amino-N-Isobutylphenylsulfonamido)-3-Hydroxy-1-Phenylbutan-2-Yl)Carbamate Ethanolate
CAS:(3R,3As,6Ar)-Hexahydrofuro[2,3-B]Furan-3-Yl ((2S,3R)-4-(4-Amino-N-Isobutylphenylsulfonamido)-3-Hydroxy-1-Phenylbutan-2-Yl)Carbamate EthanolatePeso molecular:593.73g/molDarunavir ethanolate- Bio-X ™
CAS:Darunavir is an HIV protease inhibitor that is used in the treatment of HIV-1 infection. This drug inhibits HIV-1 protease from binding and catalyzing by attaching to the enzyme and preventing HIV replication. Darunavir is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C27H37N3O7S·C2H6OPureza:Min. 99 Area-%Forma y color:PowderPeso molecular:593.73 g/molDarunavir Ethanolate
CAS:Fórmula:C27H37N3O7S·C2H6OForma y color:White To Off-White SolidPeso molecular:547.67 46.07Darunavir Ethanolate
CAS:Producto controladoApplications Darunavir Ethanolate (Prezista) is an HIV protease inhibitor. Derivative of Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product. References Holmstock, N. et al.: Drug Metab. Disp., 40, 1473 (2012); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),Fórmula:C27H37N3O7S·C2H6OForma y color:Off-WhitePeso molecular:593.73Darunavir Ethanolate
CAS:Darunavir is a HIV-1 protease inhibitor used orally in the treatment of patients with multi-drug resistant HIV-1 infection (Ghosh, 2007). It has also been shown to be effective against other infectious diseases such as hepatitis C virus and SARS coronavirus. Metabolized by cytochrome P450 3A (CYP3A) isoenzymes, darunavir is often administered together with ritonavir that prolongs its bioavaiability, giving a terminal elimination half-life (t1/2) of 15 hours (Back, 2008). The effect of darunavir on natural compounds such as matrix proteins and toll-like receptor activity has also been studied via high performance liquid chromatography (HPLC) experiments.Fórmula:C27H37N3O7S·C2H6OPureza:Min. 95%Forma y color:White PowderPeso molecular:593.73 g/mol
![(3R,3As,6Ar)-Hexahydrofuro[2,3-B]Furan-3-Yl ((2S,3R)-4-(4-Amino-N-Isobutylphenylsulfonamido)-3-Hyd…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F54%2Fthumb%2FOR1027276.jpg&w=3840&q=75)
