CAS 64-72-2: Clorotetraciclina hidrocloruro
Descripción:
Clorotetraciclina hidrocloruro es un antibiótico de amplio espectro que pertenece a la clase de las tetraciclinas, utilizado principalmente en medicina veterinaria y en algunas aplicaciones humanas. Se caracteriza por su apariencia cristalina amarilla y es soluble en agua, lo que facilita su uso en diversas formulaciones. El compuesto exhibe propiedades antibacterianas al inhibir la síntesis de proteínas en las bacterias, lo que lo hace efectivo contra una amplia gama de organismos Gram-positivos y Gram-negativos. Clorotetraciclina hidrocloruro se utiliza a menudo en el tratamiento de infecciones, así como en entornos agrícolas para promover el crecimiento del ganado. Su mecanismo de acción implica la unión a la subunidad ribosomal 30S, impidiendo la unión de aminoacil-tRNA, interrumpiendo así el proceso de traducción. Aunque generalmente es bien tolerado, puede causar efectos secundarios como trastornos gastrointestinales y fotosensibilidad. Además, el uso de tetraciclinas ha suscitado preocupaciones sobre la resistencia a los antibióticos, lo que requiere una cuidadosa consideración de su aplicación tanto en medicina humana como veterinaria.
Fórmula:C22H23ClN2O8·ClH
InChI:InChI=1S/C22H23ClN2O8.ClH/c1-21(32)7-6-8-15(25(2)3)17(28)13(20(24)31)19(30)22(8,33)18(29)11(7)16(27)12-10(26)5-4-9(23)14(12)21;/h4-5,7-8,15,26,28-29,32-33H,6H2,1-3H3,(H2,24,31);1H/t7-,8-,15-,21-,22-;/m0./s1
Clave InChI:InChIKey=CBHYYLPALVVVEY-MRFRVZCGSA-N
SMILES:O[C@]12[C@]([C@H](N(C)C)C(O)=C(C(N)=O)C1=O)(C[C@]3(C(=C2O)C(=O)C=4C([C@@]3(C)O)=C(Cl)C=CC4O)[H])[H].Cl
Sinónimos:- (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
- (2Z,4S,4aS,6S,12aS)-2-[amino(hydroxy)methylidene]-7-chloro-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
- 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
- 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
- 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
- 2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5aα,6β,12aα)]-
- 7-Chlorotetracycline hydrochloride
- 7-Chlorotetracycline monohydrochloride
- Aureociclina
- Aureocycline
- Aureomycin monohydrochloride
- Ver más sinónimos
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Chlortetracycline for system suitability CRS
CAS:Chlortetracycline for system suitability CRSFórmula:C22H24Cl2N2O8Peso molecular:515.3406CHLORTETRACYCLINE HYDROCHLORIDE CRS
CAS:CHLORTETRACYCLINE HYDROCHLORIDE CRSFórmula:C22H24Cl2N2O8Forma y color:Yellow. Powder.Peso molecular:515.3406CHLORTETRACYCLINE HYDROCHLORIDE RS
CAS:CHLORTETRACYCLINE HYDROCHLORIDE RSFórmula:C22H24Cl2N2O8Peso molecular:515.3406Chlortetracycline Hydrochloride
CAS:Fórmula:C22H23ClN2O8·HClPureza:>80.0%(HPLC)Forma y color:White to Yellow powder to crystalPeso molecular:515.34Chlorotetracycline hydrochloride 100 µg/mL in Acetonitrile/Water
CAS:Fórmula:C22H23ClN2O8·ClHForma y color:Single SolutionPeso molecular:515.34Chlortetracycline hydrochloride, can be used as secondary standard
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C22H24Cl2N2O8Forma y color:Yellow, Crystalline powderPeso molecular:515.34Chlorotetracycline monohydrochloride, Antibiotic for Culture Media Use Only
CAS:Chlorotetracycline monohydrochloride is an antibiotic compound specifically designed for culture media use. It is derived from a naturally occurring tetracycline produced by the bacterium *Streptomyces aureofaciens*. As a broad-spectrum antibiotic, chlorotetracycline functions by inhibiting protein synthesis in susceptible bacteria. It binds to the 30S subunit of the bacterial ribosome, blocking the attachment of aminoacyl-tRNA to the ribosomal acceptor site, which effectively halts translational elongation. This compound is widely used in culture media to selectively inhibit susceptible bacterial strains, thus allowing for the isolation and study of specific microorganisms. Scientists utilize chlorotetracycline monohydrochloride in both research and diagnostic laboratories to ensure the growth of targeted microorganisms while preventing contamination by unwanted bacterial species. Its application is crucial in maintaining the integrity of bacterial cultures, especially in environments where selective inhibition is essential for experimental success.Fórmula:C22H24Cl2N2O8Pureza:(Chlortetracycline Hcl) Min. 89.5%Forma y color:Yellow PowderPeso molecular:515.34 g/mol2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride,(4S,4aS,5aS,6S,12aS)-
CAS:Fórmula:C22H24Cl2N2O8Pureza:95%Forma y color:SolidPeso molecular:515.34056Chlortetracycline hydrochloride
CAS:Chlortetracycline hydrochloridePureza:techForma y color:Yellow SolidPeso molecular:515.34g/molChlortetracycline hydrochloride, specified according to the requirements of Ph.Eur.
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C22H24Cl2N2O8Forma y color:Yellow, PowderPeso molecular:515.34Chlorotetracycline monohydrochloride, Antibiotic for Culture Media Use Only
CAS:Chlorotetracycline monohydrochloride is an antibiotic designed for culture media use. It is derived from the bacterium *Streptomyces aureofaciens*, and functions primarily by inhibiting bacterial protein synthesis. This action prevents the attachment of aminoacyl-tRNA to the ribosomal acceptor site, effectively halting the growth of bacteria by disrupting protein production, which is essential for their survival and replication. In scientific applications, Chlorotetracycline monohydrochloride is used to selectively suppress bacterial growth in culture media, ensuring that only desired microorganisms are cultivated. This selectivity is crucial when studying specific microbial communities or when isolating particular strains without interference from other bacterial species. Its efficacy in inhibiting a broad spectrum of bacteria makes it a valuable tool in microbiological research and development of culture methodologies.Fórmula:C22H24Cl2N2O8Pureza:(Chlortetracycline Hcl) Min. 89.5%Peso molecular:515.34 g/molChlortetracycline hydrochloride
CAS:Chlortetracycline hydrochlorideFórmula:C22H24ClN2O8 / C22H23ClN2O8HClForma y color:Light YellowPeso molecular:479.12212Chlortetracycline-13C-d3 Hydrochloride (Technical Grade)
CAS:Producto controladoApplications Chlortetracycline-13C-d3 Hydrochloride is a labelled analog of Chlortetracycline Hydrochloride (C426500), which is an antibiotic substance isolated from the substrate of Streptomyces aureofaciens. Chlortetracycline is an antimicrobial and antibacterial. References Skaletzki, B., et al.: Pharmazie, 29, 424 (1974), Martinez, M., et al.: Biochemistry, 40, 11965 (2001), Davidson, P., et al.: Food Technol., 55, 69 (2002), de la Fuente, R., et al.: Br. J. Pharmacol., 149, 551 (2006),Fórmula:C21CH20D3ClN2O8·HClForma y color:NeatPeso molecular:534.386Chlortetracycline Hydrochloride
CAS:Producto controladoApplications Chlortetracycline is an antibiotic substance isolated from the substrate of Streptomyces aureofaciens. Chlortetracycline is an antimicrobial and antibacterial.Chlortetracycline contains an undetermined amount of epi-chlortetracycline. References Skaletzki, B., et al.: Pharmazie, 29, 424 (1974), Martinez, M., et al.: Biochemistry, 40, 11965 (2001), Davidson, P., et al.: Food Technol., 55, 69 (2002), de la Fuente, R., et al.: Br. J. Pharmacol., 149, 551 (2006),Fórmula:C22H23ClN2O8·ClHForma y color:Light Yellow To YellowPeso molecular:515.34Chlortetracycline hydrochloride
CAS:Chlortetracycline HCl (Isphamycin): broad-spectrum, bacteriostatic, halts protein synthesis in bacteria and protozoa.Fórmula:C22H23ClN2O8·HClPureza:99.68%Forma y color:Odorless Yellow SolidPeso molecular:515.35Chlortetracycline hydrochloride
CAS:Fórmula:C22H23ClN2O8·HClPureza:≥ 89.5% (Chlortetracycline HCl, anhydrous)Forma y color:Yellow powderPeso molecular:515.34Chlortetracycline Hydrochloride
CAS:Producto controladoFórmula:C22H23ClN2O8·ClHForma y color:NeatPeso molecular:515.34
