CAS 64-75-5: (-)-Clorhidrato de tetraciclina
Descripción:
(-)-Clorhidrato de tetraciclina es un antibiótico de amplio espectro que pertenece a la clase de las tetraciclinas, utilizado principalmente para tratar diversas infecciones bacterianas. Se caracteriza por su compleja estructura policíclica, que incluye cuatro anillos fusionados, lo que contribuye a su capacidad para inhibir la síntesis de proteínas en las bacterias al unirse a la subunidad ribosomal 30S. Este compuesto se presenta típicamente como una sal de clorhidrato, lo que mejora su solubilidad en agua. (-)-Clorhidrato de tetraciclina exhibe un color amarillo a naranja y es sensible a la luz, lo que puede llevar a su degradación. Es efectivo contra una amplia gama de bacterias grampositivas y gramnegativas, así como algunos protozoos. La sustancia también es conocida por sus propiedades antiinflamatorias y a veces se utiliza en el tratamiento del acné y otras afecciones cutáneas. Sin embargo, su uso puede provocar efectos secundarios, incluidos trastornos gastrointestinales y fotosensibilidad. Debido a su potencial para causar decoloración dental en niños, su uso generalmente se evita en mujeres embarazadas y niños pequeños. El almacenamiento adecuado alejado de la luz y la humedad es esencial para mantener su estabilidad y eficacia.
Fórmula:C22H24N2O8·ClH
InChI:InChI=1S/C22H24N2O8.ClH/c1-21(31)8-5-4-6-11(25)12(8)16(26)13-9(21)7-10-15(24(2)3)17(27)14(20(23)30)19(29)22(10,32)18(13)28;/h4-6,9-10,15,25,27-28,31-32H,7H2,1-3H3,(H2,23,30);1H/t9-,10-,15-,21+,22-;/m0./s1
Clave InChI:InChIKey=XMEVHPAGJVLHIG-FMZCEJRJSA-N
SMILES:O[C@@]12[C@@](C[C@]3(C(=C1O)C(=O)C=4C([C@@]3(C)O)=CC=CC4O)[H])([C@H](N(C)C)C(O)=C(C(N)=O)C2=O)[H].Cl
Sinónimos:- (2E,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
- (2Z,4S,4aS,5aS,6S,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-6,10,11,12a-tetrahydroxy-6-methyl-4a,5a,6,12a-tetrahydrotetracene-1,3,12(2H,4H,5H)-trione hydrochloride
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, hydrochloride (1:1), (4S,4aS,5aS,6S,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, (4S,4aS,5aS,6S,12aS)-
- 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, monohydrochloride, [4S-(4α,4aα,5aα,6β,12aα)]-
- 4-(Dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-2-naphthalenecarboxamide hydrochloride
- 4-(Dimethylamino)-3,6,10,12,12A-Pentahydroxy-6-Methyl-1,11-Dioxo-1,4,4A,5,5A,6,11,12A-Octahydrotetracene-2-Carboxamide Hydrochloride (1:1)
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Tetracycline hydrochloride, BP, Ph. Eur. grade
CAS:Fórmula:C22H24N2O8·HClPureza:(HPLC) 95.0 - 102.0 %Forma y color:Yellow crystalline powderPeso molecular:480.91Tetracycline hydrochloride
CAS:Tetracycline hydrochlorideFórmula:C22H24N2O8·ClHPureza:By hplc: 97.7% by area (Typical Value in Batch COA)Forma y color: yellow powderPeso molecular:480.90g/molTetracycline hydrochloride
CAS:Tetracycline hydrochloride is a broad-spectrum antibiotic, blocking protein synthesis in bacteria and used in bone histomorphometry.Fórmula:C22H24N2O8·HClPureza:97.85% - 99.43%Forma y color:Off-White PowderPeso molecular:480.9Tetracycline hydrochloride
CAS:Tetracycline hydrochlorideFórmula:C22H24N2O8HClPureza:97.5%Forma y color:Yellow SolidPeso molecular:480.12994Tetracycline Hydrochloride
CAS:Producto controladoFórmula:C22H24N2O8·ClHForma y color:NeatPeso molecular:480.90Tetracycline hydrochloride 100 µg/mL in Acetonitrile
CAS:Fórmula:C22H24N2O8·ClHForma y color:Single SolutionPeso molecular:480.90Tetracycline Hydrochloride (TC) for tissue culture, 95%
CAS:Fórmula:C22H24N2O8·HClPureza:min. 95%Forma y color:Yellow, Crystalline powderPeso molecular:480.90Tetracycline hydrochloride, 96%
CAS:Tetracycline hydrochloride is used to induce apoptosis in osteoclasts. It is used to treat acne and other skin infections, respiratory tract infections like pneumonia, genital, urinary infections, leptospirosis, helicobacter pylori, taxoplasmosis, mycoplasma, psittacosis for dog and cats. It also works more effectively in animals that have tick-borne infections. It is also useful in cell culture applications. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C22H25ClN2O8Pureza:96%Forma y color:Yellow, Crystals or powder or crystalline powderPeso molecular:480.90Tetracycline hydrochloride, can be used as secondary standard
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C22H25ClN2O8Forma y color:Yellow, PowderPeso molecular:480.90
