CAS 67-45-8: Furazolidona
Descripción:
Furazolidona es un derivado sintético de nitrofuran con la fórmula química C8H8N4O5. Se conoce principalmente por sus propiedades antimicrobianas y se utiliza en el tratamiento de diversas infecciones bacterianas y protozoarias. El compuesto presenta una apariencia cristalina de color amarillo a naranja y es soluble en agua y alcohol, lo que facilita su uso en formulaciones farmacéuticas. Furazolidona actúa inhibiendo los sistemas enzimáticos bacterianos, particularmente aquellos involucrados en el metabolismo energético, y es efectivo contra una variedad de patógenos, incluyendo algunas cepas de Escherichia coli y Giardia lamblia. Sin embargo, su uso ha disminuido debido a preocupaciones sobre posibles efectos secundarios, incluyendo trastornos gastrointestinales y el riesgo de mutagenicidad. Además, es importante señalar que Furazolidona no está aprobado para su uso en animales productores de alimentos en varios países debido a estas preocupaciones de seguridad. Al igual que con cualquier medicamento, es esencial usar Furazolidona bajo la guía de un profesional de la salud para garantizar una aplicación adecuada y un monitoreo de los efectos adversos.
Fórmula:C8H7N3O5
InChI:InChI=1S/C8H7N3O5/c12-8-10(3-4-15-8)9-5-6-1-2-7(16-6)11(13)14/h1-2,5H,3-4H2
Clave InChI:InChIKey=PLHJDBGFXBMTGZ-UHFFFAOYSA-N
SMILES:C(=NN1C(=O)OCC1)C=2OC(N(=O)=O)=CC2
Sinónimos:- 2-Furanmethanimine,5-Nitro-N-(2-Oxo-3-Oxazolidinyl)-
- 2-Oxazolidinone, 3-[(5-nitrofurfurylidene)amino]-
- 2-Oxazolidinone, 3-[[(5-nitro-2-furanyl)methylene]amino]-
- 2-Oxazolidone, 3-[[(5-nitro-2-furanyl)methylene]amino]-
- 3-(5'-Nitrofurfurylideneamino)-2-oxazolidinone
- 3-(5-Nitrofurfurylideneamino)-2-Oxazolidone
- 3-(5-aci-Nitro-2(5H)-furylidenemethylimino)-2-oxooxazolidinium hydroxide, inner salt
- 3-[(5-Nitrofurfurylidene)amino]-2-oxazolidinone
- 3-[2-(5-Nitrofuran-2-Yl)Ethenyl]-1,3-Oxazolidin-2-One
- 3-[[(5-Nitro-2-furanyl)methylene]amino]-2-oxazolidinone
- 3-{[(1E)-(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one
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Encontrado 14 productos.
Furazolidone, 98%
CAS:Monoamine oxidase inhibitor This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C8H7N3O5Pureza:98%Forma y color:Powder, YellowPeso molecular:225.16Furazolidone
CAS:Furazolidone is an antimicrobial agent that belongs to the group of synthetic nitrofurans. Furazolidone inhibits bacterial growth by binding to nuclear DNA, which prevents transcription and replication. The high frequency of human activity has been shown using a patch-clamp technique on human erythrocytes. This active form is metabolized through a number of metabolic transformations, including hydrolysis by esterases or glucuronidases, oxidation by cytochrome P450 enzymes, reduction by glutathione reductase, or conjugation with glucuronic acid. Furazolidone also specifically binds to markers expressed at high levels in Mycobacterium tuberculosis strains (e.g., ESX-1 secretion system protein) and inhibits cell growth in culture.Fórmula:C8H7N3O5Pureza:Min. 95%Forma y color:Yellow PowderPeso molecular:225.16 g/molFurazolidone
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFórmula:C8H7N3O5Forma y color:Yellow PowderPeso molecular:225.038572-Oxazolidinone, 3-[[(5-nitro-2-furanyl)methylene]amino]-
CAS:Fórmula:C8H7N3O5Pureza:98%Forma y color:SolidPeso molecular:225.158283-{[(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one
CAS:Pureza:98.0%Forma y color:Liquid, No data available.Peso molecular:225.038570324Furazolidone
CAS:Furazolidone (Furoxone), a nitrofuran derivative, inhibits AML1-ETO transformed cells with IC50 value of 12.7 μM.Fórmula:C8H7N3O5Pureza:99.96%Forma y color:Yellow Crystals From Dmf (N N-Dimethylformamide) SolidPeso molecular:225.16PharmaVetResiMix 7 Nitroimidazoles-v13 10 µg/mL in Methanol
CAS:Producto controlado- 14885-29-1
- 16773-42-5
- 19387-91-8
- 35175-14-5
- 42116-76-7
- 443-48-1
- 4812-40-2
- 551-92-8
- 59-87-0
- 67-45-8
- 70028-95-4
- 7681-76-7
- 936-05-0
Forma y color:MixtureFurazolidone
CAS:Applications Antimicrobial.Environmental contaminants; Food contaminants; Heat processing contaminants References Yurchenco, J.A., et al.: Antimicrob. Chemother., 3, 1035 (1953), Sharma, C., et al.: J. Clin. Microbiol., 36, 756 (1998),Fórmula:C8H7N3O5Forma y color:YellowPeso molecular:225.16Furazolidone
CAS:Fórmula:C8H7N3O5Pureza:>98.0%(HPLC)Forma y color:Light yellow to Amber to Dark green powder to crystalPeso molecular:225.16Furazolidone
CAS:Fórmula:C8H7N3O5Pureza:≥ 98.0% (dried basis)Forma y color:Yellow crystalline powderPeso molecular:225.16
![2-Oxazolidinone, 3-[[(5-nitro-2-furanyl)methylene]amino]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00ILIS.jpg&w=3840&q=75)
![3-{[(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF358121.jpg&w=3840&q=75)
