
CAS 68-41-7: (+)-Cicloserina
Descripción:
(+)-Cicloserina, con el número CAS 68-41-7, es un aminoácido cíclico que actúa como antibiótico y se utiliza principalmente en el tratamiento de la tuberculosis. Se caracteriza por su estructura única, que incluye un anillo de cinco miembros que contiene dos grupos funcionales: un grupo amino y un grupo hidroxilo. Este compuesto presenta un centro quiral, lo que resulta en su designación como el enantiómero (+), que es biológicamente activo. (+)-Cicloserina actúa inhibiendo la síntesis de la pared celular bacteriana, dirigiéndose específicamente a la enzima D-alanina racemasa, que es crucial para la producción de D-alanina, un componente del peptidoglicano en las paredes celulares bacterianas. La sustancia es soluble en agua y presenta una estabilidad moderada en condiciones estándar. Sin embargo, puede ser sensible a la luz y la humedad, lo que requiere condiciones de almacenamiento adecuadas. Los efectos secundarios pueden incluir síntomas neurológicos, que requieren monitoreo durante el tratamiento. En general, (+)-Cicloserina es un compuesto importante en la terapia antimicrobiana, particularmente para cepas resistentes a medicamentos de Mycobacterium tuberculosis.
Fórmula:C3H6N2O2
InChI:InChI=1S/C3H6N2O2/c4-2-1-7-5-3(2)6/h2H,1,4H2,(H,5,6)/t2-/m1/s1
Clave InChI:InChIKey=DYDCUQKUCUHJBH-UWTATZPHSA-N
SMILES:N[C@H]1C(=O)NOC1
Sinónimos:- (4R)-3-Oxoisoxazolidin-4-Aminium
- (4R)-4-Amino-1,2-Oxazolidin-3-One
- (4R)-4-Amino-3-isoxazolidinone
- (R)-(+)-Cycloserine
- (R)-4-Amino-3-Isoxazolidinone
- (R)-4-Amino-3-Isoxazolidone
- (R)-4-Amino-3-isooxazolidinone
- (R)-4-Amino-Isoxazolidin-3-One
- (R)-4-Aminoisoxazolidin-3-one
- 3-Isoxazolidinone, 4-amino-, (+)-
- 3-Isoxazolidinone, 4-amino-, (4R)-
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D-Cycloserine, 98+%
CAS:Cycloserine is an amino acid analog antibiotic used for the treatment of tuberculosis and rarely used for the treatment of noninfectious diseases. It acts as a competitive inhibitor of D-alanine during peptidoglycan synthesis. It inhibits bacterial cell wall biosynthesis and prevents the conversion of D-Alanine to L-Alanine. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C3H6N2O2Pureza:98+%Forma y color:Powder or crystals, White to pale cream or pale yellowPeso molecular:102.09Cycloserine
CAS:Antibiotics nesoiFórmula:C3H6N2O2Forma y color:White Off-White PowderPeso molecular:102.093-Isoxazolidinone, 4-amino-, (4R)-
CAS:Fórmula:C3H6N2O2Pureza:98%Forma y color:SolidPeso molecular:102.0919D-Cycloserine
CAS:Fórmula:C3H6N2O2Pureza:≥ 900μg/mgForma y color:White to off-white powderPeso molecular:102.09D-Cycloserine, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C3H6N2O2Pureza:98%Forma y color:White to light yellow, Powder or crystalsPeso molecular:102.09D-Cycloserine (D-CSR), 98%
CAS:Fórmula:C3H6N2O2Pureza:min. 98%Forma y color:White to pale yellow, Powder, Clear, Colorless to pale yellow to Light pinkPeso molecular:102.09D-Cycloserine
CAS:D-Cycloserine is a antibiotic and NMDA receptor partial agonist with action on bacterial cell wall synthesis and modulation of NMDA receptors and is used for treating tuberculosis and studying neuropsychiatric disorders.Fórmula:C3H6N2O2Pureza:Min. 98 Area-%Forma y color:PowderPeso molecular:102.09 g/molD-Cycloserine
CAS:Producto controladoApplications D-Cycloserine inhibits cell wall biosynthesis (D-Ala peptide bond formation). D-Cycloserine also prevents conversion of D-Ala to L-Ala. D-Cycloserine is an bacteriostatic. D-Cycloserine is an antibiotic against Gram-negative bacteria. There is evidence that D-cycloserine can enhance neuronal changes that lead to learning. References Lamb., J.W., et al.: Anal. Profiles Drug Subs., 1, 53 (1972), Gentry-Weeks, C., et al.: J. Biol. Chem., 268, 7298 (1993), Alexander, F., et al.: Eur. J. Biochem., 219, 953 (1994), Auger, S., et al.: Biochimie, 87, 231 (2005); Chem and Eng. News p. 12, Dec. 7/14 (2015)Fórmula:C3H6N2O2Forma y color:NeatPeso molecular:102.09D-Cycloserine
CAS:D-CycloserineFórmula:C3H6N2O2Pureza:Assay: 982.8ug/mg (Typical Value in Batch COA)Forma y color: white to pale yellowish crystalline powderPeso molecular:102.09g/molD-Cycloserine
CAS:Originally, D-cycloserine has been used as an antibiotic in the treatment of tuberculosis. More recently, it has found application in treating anxiety disorders (see the review by S.G.Hofmann et al.). Acting as a partial agonist of the NMDA receptor, the compound reduces neuropathic pain.Fórmula:C3H6N2O2Pureza:> 99%Forma y color:White PowderPeso molecular:102.09D-Cycloserine
CAS:D-Cycloserine (RO-1-9213) is an antibiotic for drug-resistant TB, used with other TB drugs.Fórmula:C3H6N2O2Pureza:99.01% - 99.83%Forma y color:Crystals SolidPeso molecular:102.09D-Cycloserine-15N,D3
CAS:Producto controladoApplications Isotope labelled D-Cycloserine inhibits cell wall biosynthesis (D-Ala peptide bond formation). D-Cycloserine also prevents conversion of D-Ala to L-Ala. D-Cycloserine is an bacteriostatic. D-Cycloserine is an antibiotic against Gram-negative bacteria. References Lamb., J.W., et al.: Anal. Profiles Drug Subs., 1, 53 (1972), Gentry-Weeks, C., et al.: J. Biol. Chem., 268, 7298 (1993), Alexander, F., et al.: Eur. J. Biochem., 219, 953 (1994), Auger, S., et al.: Biochimie, 87, 231 (2005),Fórmula:C3D3H315NNO2Forma y color:NeatPeso molecular:106.104