CAS 70458-96-7: norfloxacina
Descripción:
norfloxacina es un antibiótico fluoroquinolona sintético que se utiliza principalmente para tratar infecciones bacterianas, particularmente aquellas que afectan el tracto urinario y el sistema gastrointestinal. Funciona inhibiendo la girasa del ADN bacteriano y la topoisomerasa IV, enzimas críticas para la replicación y reparación del ADN, evitando así el crecimiento bacteriano. norfloxacina se caracteriza por su actividad de amplio espectro contra bacterias Gram-negativas y algunas Gram-positivas. Se administra típicamente por vía oral y se absorbe bien en el tracto gastrointestinal, aunque su biodisponibilidad puede verse afectada por la presencia de iones metálicos divalentes y trivalentes, que pueden formar complejos insolubles. La sustancia se considera generalmente que tiene un perfil de seguridad favorable, pero puede causar efectos secundarios como trastornos gastrointestinales, efectos en el sistema nervioso central y, en raras ocasiones, daño en los tendones. norfloxacina también está sujeto a resistencia, lo que puede limitar su efectividad. Al igual que con todos los antibióticos, es esencial usar norfloxacina de manera juiciosa para minimizar el desarrollo de resistencia y preservar su eficacia en el tratamiento de infecciones.
Fórmula:C16H18FN3O3
InChI:InChI=1S/C16H18FN3O3/c1-2-19-9-11(16(22)23)15(21)10-7-12(17)14(8-13(10)19)20-5-3-18-4-6-20/h7-9,18H,2-6H2,1H3,(H,22,23)
Clave InChI:InChIKey=OGJPXUAPXNRGGI-UHFFFAOYSA-N
SMILES:C(C)N1C=2C(C(=O)C(C(O)=O)=C1)=CC(F)=C(C2)N3CCNCC3
Sinónimos:- 1,4-Dihydro-1-Ethyl-6-Fluoro-4-Oxo-7-(1-Piperazinyl)-3-Quinolinecarboxylic Acid
- 1-Ethyl-6-Fluoro-4-Oxo-7-Piperazin-1-Yl-Quinoline-3-Carboxylic Acid
- 1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
- 1-Ethyl-6-fluoro-1,4-dihydro-7-(1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid
- 1-Ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
- 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid
- 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid
- 2-Hydroxypropanoic Acid
- 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)-
- 4803P
- Am 715
- Ver más sinónimos
Ordenar por
Norfloxacin for system suitability CRS
CAS:Norfloxacin for system suitability CRSFórmula:C16H18FN3O3Peso molecular:319.3308Norfloxacin for peak identification CRS
CAS:Norfloxacin for peak identification CRSFórmula:C16H18FN3O3Peso molecular:319.3308Norfloxacin
CAS:Norfloxacin (MK-0366)(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.Fórmula:C16H18FN3O3Pureza:100% - 99.83%Forma y color:White To Light-Yellow Crystalline Powder SolidPeso molecular:319.33Norfloxacin, 98%, Analytical standard
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C16H18FN3O3Pureza:98%Forma y color:White to yellow, PowderPeso molecular:319.34Norfloxacin
CAS:It finds it application as a fluorinated quinolone antibacterial. It is clinically used to treat urinary tract infections and prostatitis. In neutrophils from cirrhotic subjects, norfloxacin increases expression of IL-10 and heme oxygenase 1 (HO-1) and decreases expression of pro-inflammatory cytokines. Additionally, when complexed with gold(III), norfloxacin binds DNA and inhibits cellular proliferation in several cancer cell lines. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C16H18FN3O3Forma y color:Cream to yellowish, Crystalline powderPeso molecular:319.34Smart Solutions™ v59 PharmaVetResiMix Kit 1
CAS:- 100-90-3
- 113507-06-5
- 115550-35-1
- 117704-25-3
- 119478-55-6
- 1220-83-3
- 122-11-2
- 123997-26-2
- 127-71-9
- 127-79-7
- 144-82-1
- 144-83-2
- 14698-29-4
- 148-79-8
- 149676-40-4
- 155569-91-8
- 19562-30-2
- 20559-55-1
- 2447-57-6
- 28657-80-9
- 31430-15-6
- 31431-39-7
- 389-08-2
- 42835-25-6
- 43210-67-9
- 515-64-0
- 51940-44-4
- 53716-50-0
- 54029-12-8
- 54965-21-8
- 57-67-0
- 57-68-1
- 58306-30-2
- 59-40-5
- 63-74-1
- 651-06-9
- 68-35-9
- 68786-66-3
- 70288-86-7
- 70458-96-7
- 71751-41-2
- 72-14-0
- 723-46-6
- 729-99-7
- 74011-58-8
- 75184-71-3
- 79660-72-3
- 80-08-0
- 80-32-0
- 80-35-3
- 80983-34-2
- 82419-36-1
- 85721-33-1
- 88254-99-3
- 91296-86-5
- 91296-87-6
- 93106-60-6
- 948-71-0
- 98079-52-8
Forma y color:MixtureNorfloxacin
CAS:Norfloxacin is a fluoroquinolone antibiotic with action on bacterial DNA gyrase and topoisomerase IV and is used for treating urinary tract infections and gonorrhea.Fórmula:C16H18FN3O3Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:319.33 g/molNorfloxacin
CAS:Stability Hygroscopic Applications Pefloxacin derivative as antibacterial. Fluorinated quinolone antibacterial.This compound is a contaminant of emerging concern (CECs). References Koga, H., et al.: J. Med. Chem., 23, 1358 (1980), Hirai, K., et al.: Antimicrob. Agents Chemother., 19, 188 (1981), Holmes, B., et al.: Drugs, 30, 482 (1985),Fórmula:C16H18FN3O3Forma y color:Light YellowPeso molecular:319.33Norfloxacin 100 µg/mL in Acetonitrile
CAS:Fórmula:C16H18FN3O3Forma y color:Single SolutionPeso molecular:319.33Norfloxacin
CAS:Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structureFórmula:C16H18FN3O3Forma y color:White Pale Yellow PowderPeso molecular:319.13322
