CAS 76824-35-6: Famotidina
Descripción:
Famotidina es un antagonista del receptor H2 de histamina que se utiliza principalmente para tratar condiciones relacionadas con el exceso de ácido estomacal, como la enfermedad por reflujo gastroesofágico (ERGE) y las úlceras pépticas. Funciona inhibiendo la acción de la histamina en los receptores H2 de las células parietales gástricas, reduciendo así la secreción de ácido gástrico. Famotidina se caracteriza por su fórmula química C8H10N8O2S, y tiene un peso molecular de aproximadamente 337.43 g/mol. La sustancia aparece como un polvo cristalino blanco a blanco sucio, que es soluble en agua y ligeramente soluble en alcohol. Famotidina se administra típicamente por vía oral y está disponible en varias formulaciones, incluyendo tabletas y suspensión oral. Su farmacocinética incluye una rápida absorción, con concentraciones plasmáticas máximas que ocurren dentro de unas pocas horas después de la administración. Famotidina generalmente es bien tolerado, con efectos secundarios comunes que incluyen dolor de cabeza, mareos y trastornos gastrointestinales. Es importante tener en cuenta que Famotidina puede interactuar con otros medicamentos, por lo que se debe consultar a un proveedor de atención médica antes de su uso.
Fórmula:C8H15N7O2S3
InChI:InChI=1S/C8H15N7O2S3/c9-6(15-20(12,16)17)1-2-18-3-5-4-19-8(13-5)14-7(10)11/h4H,1-3H2,(H2,9,15)(H2,12,16,17)(H4,10,11,13,14)
Clave InChI:InChIKey=XUFQPHANEAPEMJ-UHFFFAOYSA-N
SMILES:N(C(=N)N)C1=NC(CSCCC(NS(N)(=O)=O)=N)=CS1
Sinónimos:- 3-[(2-Diaminomethyleneaminothiazol-4-yl)methylthio]-N-sulfamoylpropionamidine
- 3-[([2-[(Diaminomethylidene)amino]-1,3-thiazol-4-yl]methyl)sulfanyl]-N-sulfamoylpropanimidamide
- 3-[({2-[(Hydrazonomethyl)amino]thiazol-4-yl}methyl)thio]-N-sulfamoylpropionamidine
- 3-[[2-(Diaminomethylideneamino)-1,3-thiazol-4-yl]methylsulfanyl]-N′-sulfamoylpropanimidamide
- 3-[[[2-[(Aminoiminomethyl)amino]-4-thiazolyl]methyl]thio]-N-(aminosulfonyl)propanimidamide
- Agufam
- Amfamox
- Antodine
- Apo-Famotidine
- Apogastine
- Bestidine
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Famotidine for system suitability CRS
CAS:Famotidine for system suitability CRSFórmula:C8H15N7O2S3Peso molecular:337.4454Famotidine
CAS:Famotidine is a selective histamine H2-receptor antagonist used in the treatment of gastric hypersecretory disorders. Famotidine is effective in the treatment of duodenal and gastric ulcers, particularly when they are caused by the prolonged use of nonsteroidal antiinflammatory drugs (NSAIDs). To improve retention in the stomach, famotidine has experimentally been formulated as buoyant tablets that remained floating for up to 10 hours in vitro (Jaimini, 2007).Fórmula:C8H15N7O2S3Pureza:Min. 98 Area-%Forma y color:White PowderPeso molecular:337.45 g/molFamotidine
CAS:Fórmula:C8H15N7O2S3Pureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:337.44Famotidine
CAS:Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structureFórmula:C8H15N7O2S3Forma y color:PowderPeso molecular:337.45Famotidine d4
CAS:Famotidine is a drug that belongs to the group of H2-receptor antagonists. It is a prodrug that is activated by hydrolysis in vivo and inhibits the gastric acid secretion by blocking the histamine-H2 receptor on parietal cells. Famotidine has been shown to reduce inflammation in squamous cell carcinoma and other tissues. It also reduces pain, swelling, and stiffness caused by rheumatoid arthritis or osteoarthritis. Famotidine binds to P-glycoprotein (Pgp) and prevents it from transporting drugs out of cells. This action inhibits the effect of nonsteroidal anti-inflammatory drugs, such as ibuprofen or naproxen, which are substrates for Pgp. Additionally, famotidine may inhibit the action of toll-like receptors which are implicated in inflammation.Fórmula:C8H11D4N7O2S3Pureza:Min. 95%Peso molecular:341.47 g/molRef: 3D-FF174875
Producto descatalogado3-[({2-[(diaminomethylidene)amino]-1,3-thiazol-4-yl}methyl)sulfanyl]-N-sulfamoylpropanimidamide
CAS:Pureza:98.0%Peso molecular:337.44000244140625Famotidine
CAS:Fórmula:C8H15N7O2S3Pureza:≥ 98.0%Forma y color:White to off-white powderPeso molecular:337.45Famotidine
CAS:Producto controladoApplications Histamine H2-receptor antagonist. Antiulcerative. References Takeda, M., et al.: Arzneim.-Forsch., 32, 734 (1982), Miwa, M., et al.: J. Clin. Pharmacol. Ther. Toxicol., 22, 214 (1984), Takabatke, T., et al.: Eur. J. Clin. Pharmacol., 28, 327 (1985),Fórmula:C8H15N7O2S3Forma y color:White To Off-WhitePeso molecular:337.45Famotidine
CAS:Famotidine, a histamine H2-blocker, curbs gastric acid production, lowering volume and acidity.Fórmula:C8H15N7O2S3Pureza:98.93% - 99.75%Forma y color:White To Off-White Crystalline PowderPeso molecular:337.45
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