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CAS 78415-72-2: Milrinona

Descripción:
Milrinona es un inhibidor de la fosfodiesterasa que se utiliza principalmente en el tratamiento de la insuficiencia cardíaca. Funciona aumentando los niveles intracelulares de monofosfato de adenosina cíclico (cAMP), lo que lleva a una mayor contractilidad cardíaca y vasodilatación. Este mecanismo ayuda a mejorar el gasto cardíaco y reducir la carga de trabajo del corazón. Milrinona se administra típicamente por vía intravenosa y se utiliza a menudo en situaciones agudas, como durante exacerbaciones severas de insuficiencia cardíaca o después de una cirugía cardíaca. La sustancia se caracteriza por su vida media relativamente corta, lo que requiere una infusión continua para efectos terapéuticos sostenidos. Milrinona también es conocido por sus posibles efectos secundarios, que pueden incluir arritmias, hipotensión y dolor de cabeza. Su farmacocinética implica una rápida distribución y metabolismo, principalmente en el hígado, con excreción renal de sus metabolitos. Como agente terapéutico, Milrinona es valioso en el manejo de pacientes con insuficiencia cardíaca descompensada, particularmente cuando otros tratamientos son ineficaces. Sin embargo, es esencial un monitoreo cuidadoso debido a sus potentes efectos sobre la dinámica cardiovascular.
Fórmula:C12H9N3O
InChI:InChI=1S/C12H9N3O/c1-8-11(9-2-4-14-5-3-9)6-10(7-13)12(16)15-8/h2-6H,1H3,(H,15,16)
Clave InChI:InChIKey=PZRHRDRVRGEVNW-UHFFFAOYSA-N
SMILES:CC1=C(C=C(C#N)C(=O)N1)C=2C=CN=CC2
Sinónimos:
  • 1,6-Dihydro-2-methyl-6-oxo-(3,4'-bipyridine)-5-carbonitrile
  • 2-Hydroxy-6-methyl-5-(pyridin-4-yl)pyridine-3-carbonitrile
  • Corotrop
  • Corotrope
  • Milrila
  • Milrinon
  • Milrinona
  • Milrinone
  • Primacor
  • Primacor IV
  • Win 47203
  • Ver más sinónimos
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Encontrado 18 productos.
  • Milrinone

    CAS:
    Milrinone
    Pureza:≥98%
    Peso molecular:211.22g/mol

    Ref: 54-BUP15786

    1g
    296,00€
    25mg
    57,00€
    50mg
    83,00€
    100mg
    124,00€
    200mg
    163,00€
    500mg
    254,00€
  • Milrinone

    CAS:
    Fórmula:C12H9N3O

    Ref: TR-LGCFOR1539.00

    10mg
    111,00€
  • Milrinone

    CAS:
    Phosphodiesterase PDE3 inhibitor; inodilator
    Fórmula:C12H9N3O
    Pureza:Min. 95%
    Forma y color:Off-White Powder
    Peso molecular:211.22 g/mol

    Ref: 3D-FM26007

    2g
    200,00€
    5g
    333,00€
    10g
    464,00€
    25g
    968,00€
    50g
    1.421,00€
  • Milrinone

    Producto controlado
    CAS:
    Applications Selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity; cardiotonic. Potent PDE3 inhibitor. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Alousi, A.A., et al.: J. Cardiovasc Pharmacol., 5, 792 (1983), Maskin, C.S., et al.: Circulation, 67, 1065 (1983), Sinoway, L.S., et al.: J. Am. Coll. Cardiol., 2, 327 (1983), Baim, D.S., et al.: N. Engl. J. Med., 309, 748 (1983),
    Fórmula:C12H9N3O
    Forma y color:White
    Peso molecular:211.22

    Ref: TR-M344680

    5mg
    111,00€
    100mg
    218,00€
    250mg
    265,00€
  • 3-Cyano-6-methyl-5-(4-pyridyl)-2-pyridone

    CAS:
    Pureza:97.0%
    Forma y color:Solid, Crystalline
    Peso molecular:211.2239990234375

    Ref: 10-F036508

    1g
    69,00€
    5g
    A consultar
    25g
    A consultar
    100mg
    29,00€
    250mg
    39,00€
  • Milrinone

    CAS:
    Fórmula:C12H9N3O
    Pureza:>98.0%(HPLC)(N)
    Forma y color:White to Light yellow powder to crystal
    Peso molecular:211.22

    Ref: 3B-M1663

    1g
    213,00€
    100mg
    43,00€
  • Milrinone

    CAS:
    Lactams not elsewhere specified or included
    Fórmula:C12H9N3O
    Forma y color:Powder
    Peso molecular:211.07456

    Ref: 45-1443908

    500mg
    738,00€
  • Milrinone

    CAS:
    Fórmula:C12H9N3O
    Forma y color:Pale Yellow Solid
    Peso molecular:211.23

    Ref: 4Z-M-811

    5mg
    A consultar
    10mg
    A consultar
    25mg
    A consultar
    50mg
    A consultar
    100mg
    A consultar
  • Milrinone, 97%

    CAS:
    This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
    Fórmula:C12H9N3O
    Pureza:97%
    Forma y color:Powder, White to light pink
    Peso molecular:211.22

    Ref: AC-39787

    50mg
    Descatalogado
    Producto descatalogado
  • Milrinone

    Producto controlado
    CAS:
    Fórmula:C12H9N3O
    Forma y color:Neat
    Peso molecular:211.22

    Ref: 86-MM1539.00

    250mg
    A consultar
  • Milrinone - Bio-X ™

    CAS:
    Milrinone has an application for use in the treatment of heart failure. It has been shown to increase cardiac output and decrease left ventricular end diastolic pressure (LVEDP). Milrinone also increases the amount of oxygen delivered to the tissues by increasing cardiac contractility.  Milrinone is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready to use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.
    Fórmula:C12H9N3O
    Pureza:(%) Min. 95%
    Forma y color:Powder
    Peso molecular:211.22 g/mol

    Ref: 3D-BM164671

    10mg
    140,00€
  • Milrinone

    CAS:
    Fórmula:C12H9N3O

    Ref: TR-MM1539.00

    250mg
    455,00€
  • Milrinone

    CAS:
    Fórmula:C12H9N3O
    Peso molecular:211.22

    Ref: 7W-GP3826

    ne
    A consultar
  • Milrinone

    CAS:
    Fórmula:C12H9N3O
    Pureza:99%
    Forma y color:Solid
    Peso molecular:211.21935999999997

    Ref: IN-DA003S4R

    1g
    49,00€
    5g
    107,00€
    10g
    160,00€
    25g
    208,00€
    50g
    331,00€
    100g
    506,00€
    100mg
    30,00€
    250mg
    39,00€
  • Milrinone, 98+%

    CAS:
    It is used (particularly intravenously, as the lactate) for the short-term management of severe heart failure. Milrinone inhibits the action of phosphodiesterase-3 preventing degradation of cAMP. The corresponding increase in cAMP levels leads to increased activation of protein kinase A. It is a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
    Fórmula:C12H9N3O
    Pureza:98+%
    Forma y color:Pale cream to cream, Powder or crystals or crystalline powder
    Peso molecular:211.22

    Ref: 02-J62659

    10mg
    149,00€
    50mg
    A consultar
  • Milrinone

    CAS:
    Milrinone (Win 47203) is a Phosphodiesterase 3 Inhibitor. The mechanism of action of milrinone is as a Phosphodiesterase 3 Inhibitor.
    Fórmula:C12H9N3O
    Pureza:99.22% - 99.92%
    Forma y color:Solid
    Peso molecular:211.22

    Ref: TM-T1096

    25mg
    43,00€
    50mg
    57,00€
    100mg
    88,00€
    200mg
    106,00€
    500mg
    168,00€
    1mL*10mM (DMSO)
    63,00€
  • Milrinone

    CAS:
    Milrinone
    Pureza:98+%
    Forma y color:White Solid
    Peso molecular:211.22g/mol

    Ref: 54-BIM0128

    1g
    105,00€
    5g
    127,00€
    25g
    365,00€
    100g
    1.152,00€
    250mg
    37,00€
  • Milrinone-d4

    Producto controlado
    CAS:
    Fórmula:C12H5D4N3O
    Forma y color:Neat
    Peso molecular:309.278

    Ref: TR-M344682

    100mg
    9.953,00€