CAS 82586-52-5: Clorhidrato de moexipril
Descripción:
Clorhidrato de moexipril es un inhibidor de la enzima convertidora de angiotensina (ECA) que se utiliza principalmente en el tratamiento de la hipertensión. Es un profármaco que se convierte en el cuerpo en su forma activa, moexiprilato, que ejerce sus efectos farmacológicos al inhibir la conversión de angiotensina I a angiotensina II, lo que lleva a la vasodilatación y a la reducción de la presión arterial. La fórmula química de Clorhidrato de moexipril incluye una estructura compleja que presenta un derivado de prolina, lo que contribuye a su eficacia y especificidad. Se administra típicamente por vía oral y es conocido por su vida media relativamente larga, lo que permite una dosificación una vez al día. Los efectos secundarios comunes pueden incluir mareos, tos y niveles elevados de potasio, entre otros. Al igual que otros inhibidores de la ECA, está contraindicado en pacientes con antecedentes de angioedema relacionado con la terapia previa con inhibidores de la ECA y debe usarse con precaución en individuos con deterioro renal. En general, Clorhidrato de moexipril es un agente terapéutico importante en el manejo de la salud cardiovascular.
Fórmula:C27H34N2O7·ClH
InChI:InChI=1S/C27H34N2O7.ClH/c1-5-36-27(33)21(12-11-18-9-7-6-8-10-18)28-17(2)25(30)29-16-20-15-24(35-4)23(34-3)14-19(20)13-22(29)26(31)32;/h6-10,14-15,17,21-22,28H,5,11-13,16H2,1-4H3,(H,31,32);1H/t17-,21-,22-;/m0./s1
Clave InChI:InChIKey=JXRAXHBVZQZSIC-JKVLGAQCSA-N
SMILES:C([C@@H](N[C@@H](CCC1=CC=CC=C1)C(OCC)=O)C)(=O)N2CC=3C(C[C@H]2C(O)=O)=CC(OC)=C(OC)C3.Cl
Sinónimos:- (3S)-2-[(2S)-2-{[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisochinolin-3-carbons?urehydrochlorid
- (3S)-2-[(2S)-2-{[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
- (3S)-2-{N-[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]-L-alanyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride
- (3S)-2-{N-[(2S)-1-Ethoxy-1-oxo-4-phenyl-2-butanyl]-L-alanyl}-6,7-dimethoxy-1,2,3,4-tetrahydro-3-isoquinolinecarboxylic acid hydrochloride (1:1)
- (3S)-2-{N-[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]-L-alanyl}-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid hydrochloride (1:1)
- (3S-(2(R*(R*)),3R*))-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)-3-isoquinolinecarboxylic acid monohydrochloride
- 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, (3S)-, hydrochloride (1:1)
- 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, hydrochloride (1:1), (3S)-
- 3-Isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, monohydrochloride, (3S)-
- 3-Isoquinolinecarboxylic acid, 2-[2-[[1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, monohydrochloride, [3S-[2[R*(R*)],3R*]]-
- 3-isoquinolinecarboxylic acid, 2-[(2S)-2-[[(1S)-1-(ethoxycarbonyl)-3-phenylpropyl]amino]-1-oxopropyl]-1,2,3,4-tetrahydro-6,7-dimethoxy-, (3S)-, monohydrochloride
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Encontrado 7 productos.
Moexipril hydrochloride
CAS:Moexipril hydrochloride (Moexipril HCl) is a potent orally active nonsulfhydrylangiotensin converting enzyme (ACE)inhibitor, used for the treatment ofFórmula:C27H34N2O7·HClPureza:89.27%Forma y color:A Fine White To Off-White PowderPeso molecular:535.03Moexipril HCl - Bio-X ™
CAS:Moexipril is an angiotensin converting enzyme inhibitor that is used for the treatment of hypertension. This drug is a prodrug for moexiprilat and works by relaxing the blood vessels causing them to widen and lowering blood pressure. Moexipril has been shown to be effective in treating metabolic disorders such as congestive heart failure. Moexipril HCl is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C27H34N2O7Pureza:Min. 95%Forma y color:PowderPeso molecular:498.57 g/molMoexipril Hydrochloride
CAS:Drugs containing a quinoline or isoquinoline ring-system (whether or not hydrogenated) not further fusedFórmula:C27H34N2O7·HClForma y color:PowderPeso molecular:498.2366Moexipril HCl
CAS:Inhibitor of angiotensin converting enzymeFórmula:C27H35ClN2O7Pureza:Min. 95%Forma y color:Off-White PowderPeso molecular:535.03 g/molMoexipril-d5 HCl
CAS:Fórmula:C27H29D5N2O7·HClForma y color:White To Off-White SolidPeso molecular:503.61 36.46Moexipril hydrochloride
CAS:Fórmula:C27H35N2O7ClPureza:≥ 98.0%Forma y color:Conflicting attributes definedPeso molecular:535.03Moexipril HCl
CAS:Fórmula:C27H34N2O7·HClForma y color:White To Off-White SolidPeso molecular:498.58 36.46
