CAS 976-71-6: Canrenona
Descripción:
Canrenona es un compuesto sintético clasificado como un esteroide y es conocido principalmente por su papel como un diurético ahorrador de potasio. Se deriva de la espironolactona y funciona antagonizando los receptores de aldosterona, lo que ayuda en la regulación de los niveles de sodio y potasio en el cuerpo. Canrenona se utiliza a menudo en el tratamiento de condiciones como la hipertensión y el edema, particularmente en pacientes que requieren terapia diurética sin el riesgo de pérdida significativa de potasio. La sustancia se caracteriza por su baja solubilidad en agua, pero es soluble en disolventes orgánicos. Su estructura química incluye un anillo de lactona, que es esencial para su actividad biológica. Canrenona se metaboliza en el hígado, y su farmacocinética puede verse influenciada por varios factores, incluyendo la función hepática y medicamentos concurrentes. Al igual que con cualquier medicamento, los efectos secundarios potenciales pueden incluir desequilibrios electrolíticos, particularmente hiperpotasemia, y efectos hormonales debido a sus propiedades similares a las de los esteroides. En general, Canrenona es un agente terapéutico importante en el manejo del equilibrio de fluidos y la presión arterial.
Fórmula:C22H28O3
InChI:InChI=1S/C22H28O3/c1-20-9-5-15(23)13-14(20)3-4-16-17(20)6-10-21(2)18(16)7-11-22(21)12-8-19(24)25-22/h3-4,13,16-18H,5-12H2,1-2H3/t16-,17+,18+,20+,21+,22-/m1/s1
Clave InChI:InChIKey=UJVLDDZCTMKXJK-WNHSNXHDSA-N
SMILES:C[C@@]12[C@]3(CC[C@]1([C@]4([C@](CC2)([C@]5(C)C(C=C4)=CC(=O)CC5)[H])[H])[H])OC(=O)CC3
Sinónimos:- (10R,13S,17R)-10,13-dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione
- (8R,9S,10R,13S,14S,17R)-10,13-dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione
- 10,13-dimethyl-1,8,9,10,11,12,13,14,15,16-decahydro-3'H-spiro[cyclopenta[a]phenanthrene-17,2'-furan]-3,5'(2H,4'H)-dione
- 11614 R. P.
- 17-Hydroxy-3-oxo-17alpha-pregna-4,6-diene-21-carboxylic acid gamma-lactone
- 17-Hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylic acid lactone
- 17-Hydroxy-3-oxo-17α-pregna-4,6-diene-21-carboxylic acid γ-lactone
- 17alpha-(2-Carboxyethyl)-17beta-hydroxyandrosta-4,6-dien-3-one lactone
- 17alpha-Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, gamma-lactone (8CI)
- 17α-(2-Carboxyethyl)-17β-hydroxyandrosta-4,6-dien-3-one lactone
- 17α-Pregna-4,6-diene-21-carboxylic acid, 17-hydroxy-3-oxo-, γ-lactone
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Encontrado 18 productos.
Spironolactone EP Impurity F-d4 (Canrenone-d4)
CAS:Fórmula:C22H24D4O3Forma y color:Pale Yellow SolidPeso molecular:344.49Canrenone
CAS:Producto controladoMineralocorticoid (aldosterone) receptor antagonistFórmula:C22H28O3Pureza:Min. 97 Area-%Forma y color:PowderPeso molecular:340.46 g/molCanrenone, 98%
CAS:Inhibits aldosterone biosynthesis and blocks ouabain effects This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C22H28O3Pureza:98%Peso molecular:340.46Canrenone - Bio-X ™
CAS:Producto controladoCanrenone is a steroidal antimineralcorticoid that is used as a diuretic. It has been shown to reduce blood pressure and increase urine volume. Also, this drug has shown to be effective in treating hirsutism in women. Canrenone is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C22H28O3Pureza:Min. 95%Forma y color:PowderPeso molecular:340.46 g/molCanrenone-d6 (Major)
CAS:Producto controladoApplications Labelled Aldosterone antagonist. Diuretic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Sadee, W., et al.: J. Pharmacol. Exp. Ther., 185, 686 (1973), Pitt, B., et al.: Circulation, 108, 1831 (2003), Silvestre, J., et al.: J. Biol. Chem., 273, 4883 (1998), Struthers, A., et al.: Heart, 92, 1728 (2006),Fórmula:C22H22D6O3Forma y color:Light Yellow To Dark YellowPeso molecular:346.49Spironolactone EP Impurity F (Canrenone)
CAS:Fórmula:C22H28O3Forma y color:Yellow SolidPeso molecular:340.46Canrenone - 95%
CAS:Producto controladoMineralocorticoid (aldosterone) receptor antagonistFórmula:C22H28O3Pureza:Min. 95 Area-%Forma y color:PowderPeso molecular:340.46 g/molCanrenone
CAS:Impurity Spironolactone EP Impurity F Applications Canrenone (Spironolactone EP Impurity F) is an aldosterone antagonist. Diuretic. Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package References Sadee, W., et al.: J. Pharmacol. Exp. Ther., 185, 686 (1973), Pitt, B., et al.: Circulation, 108, 1831 (2003), Silvestre, J., et al.: J. Biol. Chem., 273, 4883 (1998), Struthers, A., et al.: Heart, 92, 1728 (2006),Fórmula:C22H28O3Forma y color:Light Yellow SolidPeso molecular:340.46Spironolactone Related Compound A ((2'R)-3',4'-Dihydro-5'H-spiro[androst-4,6-diene-17,2'-furan]-3,5'-dione)
CAS:Adrenal cortical hormones and their derivatives nesoiFórmula:C22H28O3Forma y color:Light Yellow Crystalline PowderPeso molecular:340.20384Canrenone
CAS:Canrenone (SC14266) is an aldosterone antagonist with potassium-sparing diuretic activity.Fórmula:C22H28O3Pureza:99.88%Forma y color:SolidPeso molecular:340.46
![3',4'-Dihydrospiro[androst-4,6-diene-17,2'(5'H)-furan]-3,5'-dione (Canrenone)](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F86%2Fthumb%2FMM0197.01-0250.jpg&w=3840&q=75)
