CAS 98319-26-7: Finasterida
Descripción:
Finasterida es un compuesto farmacéutico sintético utilizado principalmente en el tratamiento de la hiperplasia prostática benigna (HPB) y la alopecia androgenética (calvicie de patrón masculino). Funciona como un inhibidor de la 5-alfa-reductasa, bloqueando la conversión de testosterona a dihidrotestosterona (DHT), una hormona implicada en ambas condiciones. La fórmula molecular de Finasterida es C23H36N2O2, y tiene un peso molecular de aproximadamente 372.55 g/mol. La sustancia aparece como un polvo cristalino blanco a blanco amarillento y se administra típicamente por vía oral. Finasterida es conocido por su relativamente alta biodisponibilidad y se metaboliza principalmente en el hígado. Los efectos secundarios comunes pueden incluir disfunción sexual, ginecomastia y cambios de humor, aunque no todos los usuarios los experimentan. Debido a su mecanismo de acción, Finasterida está contraindicado en mujeres, particularmente durante el embarazo, ya que puede causar daño fetal. En general, Finasterida es un medicamento significativo en urología y dermatología, proporcionando beneficios terapéuticos para condiciones relacionadas con la DHT.
Fórmula:C23H36N2O2
InChI:InChI=1S/C23H36N2O2/c1-21(2,3)25-20(27)17-8-7-15-14-6-9-18-23(5,13-11-19(26)24-18)16(14)10-12-22(15,17)4/h11,13-18H,6-10,12H2,1-5H3,(H,24,26)(H,25,27)/t14-,15-,16-,17+,18+,22-,23+/m0/s1
Clave InChI:InChIKey=DBEPLOCGEIEOCV-WSBQPABSSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@@](CC3)(NC(=O)C=C4)[H])(CC1)[H])[H])(CC[C@@H]2C(NC(C)(C)C)=O)[H]
Sinónimos:- (4aR,4bS,6aS,7S,9aS,9bS)-N-tert-butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
- (4aR,4bS,6aS,7S,9aS,9bS,11aR)-N-(1,1-Dimethylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-1H-indeno[5,4-f]quinoline-7-carboxamide
- (4aR,4bS,6aS,9aS,9bS,11aR)-N-tert-butyl-4a,6a-dimethyl-2-oxo-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-indeno[5,4-f]quinoline-7-carboxamide
- 1H-Indeno[5,4-f]quinoline-7-carboxamide, N-(1,1-dimethylethyl)-2,4a,4b,5,6,6a,7,8,9,9a,9b,10,11,11a-tetradecahydro-4a,6a-dimethyl-2-oxo-, (4aR,4bS,6aS,7S,9aS,9bS,11aR)-
- 4-Azaandrost-1-ene-17-carboxamide, N-(1,1-dimethylethyl)-3-oxo-, (5α,17β)-
- Appecia
- Chibro-Proscar
- Finalo
- Finara
- Finast
- Finasterid Alternova
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Finasteride - Bio-X ™
CAS:Finasteride is an antiandrogenic drug that belongs to the group of 5-alpha reductase inhibitors, which are used for the treatment of benign prostatic hyperplasia and male pattern baldness. The conversion of testosterone to 5α-dihydrotestosterone (DHT) is blocked by type II 5α-reductase inhibition, which then results in significant increase in prostatic testosterone concentrations and minimal to moderate increases in serum and tissue DHT concentrations. A reduction in DHT concentration will cause a reduction in prostatic volume as DHT appears to be the main androgen responsible for stimulating prostatic growth. Finasteride is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C23H36N2O2Pureza:Min. 95%Forma y color:PowderPeso molecular:372.54 g/molFinasteride
CAS:Adrenal cortical hormones and their derivatives nesoiFórmula:C23H36N2O2Forma y color:White Off-White PowderPeso molecular:372.27768Finasteride, USP grade
CAS:Fórmula:C23H36N2O2Pureza:≤ 0.5%Forma y color:White or almost white powderPeso molecular:372.54Finasteride, 98%
CAS:This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C23H36N2O2Pureza:98%Forma y color:White to beige, Crystalline powderPeso molecular:372.55Finasteride
CAS:Finasteride is used as a inhibitor of steroid 5-a-reductase, antiandrogen, an intracellular enzyme that converts the androgen testosterone into 5α dihydrotestosterone. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.Fórmula:C23H36N2O2Peso molecular:372.54Finasteride
CAS:Producto controladoFórmula:C23H36N2O2Forma y color:White To Off-WhitePeso molecular:372.54Finasteride
CAS:Fórmula:C23H36N2O2Pureza:>98.0%(GC)Forma y color:White to Almost white powder to crystalPeso molecular:372.55N-tert-Butyl-3-oxo-4-aza-5α-androst-1-en-17β-carboxamide
CAS:Fórmula:C23H36N2O2Pureza:98%Forma y color:SolidPeso molecular:372.5441Finasteride
CAS:Finasteride (MK-906) is an oral inhibitor of active testosterone 5-alpha-reductase and Ki value is 10 nM.Fórmula:C23H36N2O2Pureza:98.4% - 99.89%Forma y color:White To Off-White Crystalline PowderPeso molecular:372.54Finasteride
CAS:Inhibitor of 5α-reductase 5AR2; inhibitor of dihydrotestosterone synthesisFórmula:C23H36N2O2Pureza:Min. 98 Area-%Forma y color:White Off-White PowderPeso molecular:372.54 g/mol
