CAS 99614-01-4: Clorhidrato de ondansetrón
Descripción:
Clorhidrato de ondansetrón es un antagonista selectivo del receptor de serotonina 5-HT3 que se utiliza principalmente como antiemético para prevenir náuseas y vómitos causados por quimioterapia, radioterapia y cirugía. Es un polvo cristalino blanco a blanco amarillento que es soluble en agua y tiene una fórmula molecular que refleja su estructura compleja. La sustancia exhibe una alta afinidad por los receptores 5-HT3, bloqueando la acción de la serotonina, que es responsable de desencadenar náuseas y vómitos. Clorhidrato de ondansetrón se administra típicamente por vía oral o intravenosa, y su farmacocinética incluye una rápida absorción y una vida media relativamente corta, lo que requiere múltiples dosis en algunos regímenes de tratamiento. El compuesto generalmente es bien tolerado, con efectos secundarios comunes que incluyen dolor de cabeza, estreñimiento y mareos. Es importante señalar que, aunque es efectivo, el ondansetron debe usarse con precaución en pacientes con ciertas condiciones médicas, y su uso durante el embarazo debe evaluarse cuidadosamente. En general, Clorhidrato de ondansetrón es un medicamento crítico en el manejo de las náuseas y vómitos inducidos por quimioterapia, contribuyendo significativamente al confort del paciente y a la calidad de vida durante el tratamiento del cáncer.
Fórmula:C18H19N3O·ClH
InChI:InChI=1S/C18H19N3O.ClH/c1-12-19-9-10-21(12)11-13-7-8-16-17(18(13)22)14-5-3-4-6-15(14)20(16)2;/h3-6,9-10,13H,7-8,11H2,1-2H3;1H
Clave InChI:InChIKey=MKBLHFILKIKSQM-UHFFFAOYSA-N
SMILES:O=C1C=2C=3C(N(C)C2CCC1CN4C(C)=NC=C4)=CC=CC3.Cl
Sinónimos:- (+-)-2,3-Dihydro-9-Methyl-3-((2-Methylimidazol-1-Yl)Methyl)Carbazol-4(1H)-One Monohydrochloride Dihydrate
- 1,2,3,4-Tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-9H-carbazol-4-one hydrochloride
- 1,2,3,9-Tetrahydro-9-Methyl-3-[(2-Methyl-1H-Imidazol-1-Yl)Methyl]-4H-Carbazol-4-One Hydrochloride Dihydrate
- 1-methyl-N-[(3-endo)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide hydrochloride (1:1)
- 4H-Carbazol-4-One, 1,2,3,9-Tetrahydro-9-Methyl-3-((2-Methyl-1H-Imidazol-1-Yl)Methyl)-, Monohydrochloride, (+-)-, Dihydrate
- 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-, monohydrochloride
- 4H-Carbazol-4-one, 1,2,3,9-tetrahydro-9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-, hydrochloride (1:1)
- 9-Methyl-3-((2-methyl-1H-imidazol-1-yl)methyl)-4H-carbazol-4-one monohydrochloride
- 9-Methyl-3-[(2-Methylimidazol-1-Yl)Methyl]-2,3-Dihydro-1H-Carbazol-4-One Dihydrate Hydrochloride
- 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride (1:1)
- 9-methyl-3-[(2-methyl-1H-imidazol-1-yl)methyl]-1,2,3,9-tetrahydro-4H-carbazol-4-one hydrochloride dihydrate
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Encontrado 8 productos.
Ondansetron hydrochloride
CAS:Ondansetron hydrochloride (Zofran) is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiationFórmula:C18H19N3O·HClPureza:99.78%Forma y color:White PowderPeso molecular:329.82Ondansetron HCl
CAS:Fórmula:C18H19N3O·HClForma y color:White To Off-White SolidPeso molecular:293.37 36.46Ondansetron HCl
CAS:Serotonin receptor 5-HT3 antagonistFórmula:C18H20N3OClPureza:Min. 95%Forma y color:White PowderPeso molecular:329.82 g/molOndansetron hydrochloride - Bio-X ™
CAS:Ondansetron is a serotonin 5-HT3 receptor antagonist that has been shown to inhibit the effects of serotonin in the gastrointestinal tract, thereby preventing nausea and vomiting that is caused by cancer chemotherapy. Chemotherapy and radiotherapy are associated with the release of serotonin (5-HT) from enterochromaffin cells of the small intestine, initiating a vomiting reflex through stimulation of 5-HT3 receptors located on vagal afferents. Ondansetron blocks the initiation of this reflex. The drug binds to receptors on cells in the gastrointestinal tract that are normally activated by serotonin, thereby blocking its effect. Ondansetron hydrochloride is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.Fórmula:C18H20N3OClPureza:Min. 95%Forma y color:PowderPeso molecular:329.82 g/molOndansetron Hydrochloride Dihydrate
CAS:Fórmula:C18H19N3O·HCl·2H2OPureza:>98.0%(T)(HPLC)Forma y color:White to Almost white powder to crystalPeso molecular:365.86Ondansetron Hydrochloride
CAS:Producto controladoFórmula:C18H19N3O·HClForma y color:NeatPeso molecular:329.80
