Syk
Los inhibidores de Syk (tirosina quinasa del bazo) son compuestos que se dirigen a Syk, una quinasa involucrada en la señalización de células inmunitarias y la regulación de la angiogénesis. Syk desempeña un papel en las respuestas inflamatorias que pueden contribuir a la angiogénesis tumoral. Inhibir Syk puede reducir la formación de vasos sanguíneos inducida por la inflamación en los tumores, lo que convierte a estos inhibidores en herramientas valiosas en la terapia contra el cáncer y la investigación sobre inflamación. En CymitQuimica, ofrecemos una amplia gama de inhibidores de Syk de alta calidad para apoyar su investigación en inmunología, oncología y angiogénesis.
Productos de "Syk"
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MNS
CAS:MNS is a tyrosine kinases inhibitor, inhibits Syk, Src, p97 with IC50 of 2.5 μM, 29.3 μM and 1.7 μM, respectively.Fórmula:C9H7NO4Pureza:98.53%Forma y color:Yellow PowderPeso molecular:193.16Piceatannol
CAS:Fórmula:C14H12O4Pureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light red powder to crystalPeso molecular:244.25PRT-060318
CAS:PRT-060318 (P142-76) is a novel selective inhibitor of the Syk tyrosine kinase, as an approach to HIT treatment.Fórmula:C18H24N6OPureza:98.82%Forma y color:SolidPeso molecular:340.42Lanraplenib
CAS:Lanraplenib (GS-9876) is a highly selective and orally active SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases.Fórmula:C23H25N9OPureza:98.35%Forma y color:SolidPeso molecular:443.5Ref: TM-T11824LL
1mg51,00€2mg74,00€5mg99,00€10mg167,00€25mg290,00€50mg430,00€100mg633,00€1mL*10mM (DMSO)115,00€BAY 61-3606
CAS:BAY 61-3606 (Syk inhibitor IV) is a potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase activity (Ki= 7.5 nM), exhibitingFórmula:C20H18N6O3Pureza:98.94%Forma y color:SolidPeso molecular:390.4Syk Inhibitor II
CAS:Syk inhibitor II, a cell-permeable, ATP-competitive, pyrimidine-carboxamide compound, selectively and reversibly inhibits Syk (IC50 = 41 nM).Fórmula:C14H15F3N6OPureza:97.63%Forma y color:SolidPeso molecular:340.31,3-Benzodioxole, 5-(2-nitroethenyl)-
CAS:Fórmula:C9H7NO4Pureza:98%Forma y color:SolidPeso molecular:193.1562RO9021
CAS:RO9021 is an orally bioavailable, novel ATP-competitive SYK inhibitor (average IC50: 5.6 nM).Fórmula:C18H25N7OPureza:97.19%Forma y color:SolidPeso molecular:355.44Cerdulatinib hydrochloride
CAS:Cerdulatinib hydrochloride is an oral tyrosine kinase inhibitor targeting JAK1/2/3, TYK2, Syk, and 19 others with IC50 < 200 nM.Fórmula:C20H28ClN7O3SPureza:99.23%Forma y color:SolidPeso molecular:482Cerdulatinib
CAS:Cerdulatinib (PRT2070) is an novel oral dual Syk/JAK inhibitor.Fórmula:C20H27N7O3SPureza:98.74% - 99.49%Forma y color:SolidPeso molecular:445.54Ref: TM-T2487
1mg44,00€2mg55,00€5mg79,00€10mg106,00€25mg185,00€50mg283,00€100mg432,00€200mg605,00€500mg938,00€1mL*10mM (DMSO)86,00€Syk-IN-7
Syk-IN-7 (compound 17) acts as an inhibitor of spleen tyrosine kinase (SYK) [1].Fórmula:C26H31N9O4Pureza:98%Forma y color:SolidPeso molecular:533.58Flavanomarein
CAS:Flavanomarein: Antioxidant with radical scavenging, lipid peroxidation inhibition, and lipid-lowering in HepG2 cells.Fórmula:C21H22O11Pureza:97.53% - 98.63%Forma y color:SolidPeso molecular:450.39Fostamatinib Disodium
CAS:Fostamatinib Disodium (R788 Disodium) is an orally available Syk kinase inhibitor with potential anti-inflammatory and immunomodulating activities.Fórmula:C23H24FN6O9P·2NaPureza:96.13% - 98.95%Forma y color:SolidPeso molecular:624.42Ref: TM-T2605
1mg47,00€2mg55,00€5mg88,00€10mg124,00€25mg221,00€50mg374,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)116,00€OXSI-2
CAS:OXSI-2 (Syk Inhibitor) is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM.Fórmula:C18H15N3O3SPureza:98%Forma y color:Dark Orange SolidPeso molecular:353.39Cevidoplenib dimesylate
CAS:Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.Fórmula:C27H35N7O9S2Pureza:96.16%Forma y color:SolidPeso molecular:665.741,2-Benzenediol, 4-[(1E)-2-(3,5-dihydroxyphenyl)ethenyl]-
CAS:Fórmula:C14H12O4Pureza:98%Forma y color:SolidPeso molecular:244.2427TC-S 7003
CAS:TC-S 7003 (Lck Inhibitor) is a Lck inhibitor with anti-inflammatory activity that inhibits T-cell proliferation and can be used to study arthritis.Fórmula:C31H30N8OPureza:99.74%Forma y color:SolidPeso molecular:530.62Piceatannol
CAS:Piceatannol (Astringenin) is a synthetic anti-inflammatory that blocks p56lck, syk kinases, and NF-κB, made from resveratrol.Fórmula:C14H12O4Pureza:98.66% - 99.57%Forma y color:Light Tan To Yellow PowderPeso molecular:244.24R406 free base
CAS:R406 free base (R406 (free base)) is a potent Syk inhibitor.Fórmula:C22H23FN6O5Pureza:97.64% - 99.11%Forma y color:SolidPeso molecular:470.45Fostamatinib
CAS:Fostamatinib (R788)(IC50 of 41 nM), which is a prodrug of the active metabolite R406, is a Syk inhibitor. It does not work on Lyn.Fórmula:C23H26FN6O9PPureza:93.08% - 99.38%Forma y color:SolidPeso molecular:580.46Ref: TM-T6115
1mg43,00€2mg57,00€5mg88,00€10mg118,00€25mg210,00€50mg335,00€100mg548,00€500mg1.198,00€1mL*10mM (DMSO)101,00€
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