Cromatina / Epigenética
Los inhibidores de cromatina/epigenética son compuestos que modulan la estructura y función de la cromatina o interfieren con modificaciones epigenéticas, como la metilación del ADN y la modificación de histonas. Estos inhibidores son herramientas esenciales para estudiar la regulación de la expresión génica y el papel de la epigenética en enfermedades como el cáncer, los trastornos neurológicos y las anomalías del desarrollo. Al dirigirse a los procesos epigenéticos, estos inhibidores pueden alterar los patrones de expresión génica y ofrecer nuevas vías terapéuticas. En CymitQuimica, ofrecemos una amplia selección de inhibidores de cromatina/epigenética de alta calidad para apoyar su investigación en biología molecular, genética y epigenética.
Subcategorías de "Cromatina / Epigenética"
Productos de "Cromatina / Epigenética"
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VPC-70063
CAS:VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX.Fórmula:C16H12F6N2SPureza:99.93%Forma y color:SolidPeso molecular:378.34Ref: TM-T60019
1mg51,00€5mg106,00€10mg160,00€25mg283,00€50mg406,00€100mg592,00€200mg835,00€1mL*10mM (DMSO)137,00€PARP10-IN-2
CAS:PARP10-IN-2 is a potent inhibitor of PARP10, a mono-ADP-ribosyltransferase, with an IC50 value of 3.64 μM for human PARP10.PARP10-IN-2 also inhibited PARP2 andFórmula:C14H10N2O2Pureza:99.68%Forma y color:SolidPeso molecular:238.24PF-CBP1 hydrochloride
CAS:PF-CBP1 HCl selectively inhibits CREBBP bromodomain (IC50: 125 nM) and p300 (IC50: 363 nM).Fórmula:C29H37ClN4O3Pureza:97.11% - 99.02%Forma y color:SolidPeso molecular:525.08Eleven-Nineteen-Leukemia Protein IN-2
CAS:Eleven-Nineteen-Leukemia Protein IN-2 (compound 23), an ENL inhibitor, exhibits an IC50 of 10.7 nM and is utilized for leukemia research [1].Fórmula:C22H23N5O2Pureza:98%Forma y color:SolidPeso molecular:389.45PF-06821497
CAS:PF-06821497 is a selective inhibitor of EZH2 with significant tumor growth inhibition.Cost-effective and quality-assured.Fórmula:C22H24Cl2N2O5Pureza:97.88%Forma y color:SolidPeso molecular:467.34Citric acid trilithium salt tetrahydrate
CAS:Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) , the active component of Lithium, is a medicine used in the therapy ofFórmula:C6H13Li3O11Pureza:≥95%Forma y color:White Crystalline PowderPeso molecular:281.98CF53
CAS:CF53: potent, selective oral BET inhibitor; Ki <1 nM, Kd 2.2 nM, IC50 2 nM for BRD4 BD1; high affinity for BRD2/3/4/BRDT; effective anti-tumor agent.Fórmula:C24H25N7O2Pureza:99.72%Forma y color:SolidPeso molecular:443.5Ref: TM-T10773
1mg96,00€5mg212,00€10mg316,00€25mg510,00€50mg695,00€100mg940,00€1mL*10mM (DMSO)226,00€CEP-33779
CAS:CEP-33779 is a novel and selective inhibitor of JAK2 with an IC50 of 1.8±0.6 nM.Fórmula:C24H26N6O2SPureza:98.81% - ≥95%Forma y color:SolidPeso molecular:462.57Ref: TM-T6122
1mg46,00€2mg59,00€5mg87,00€10mg144,00€25mg245,00€50mg376,00€100mg560,00€500mg1.216,00€1mL*10mM (DMSO)97,00€GSK484 hydrochloride
CAS:GSK484 hydrochloride (GTPL8577) is a reversible peptidyl-arginine deiminase 4 (PAD4) inhibitor.Cost-effective and quality-assured.Fórmula:C27H32ClN5O3Pureza:98.32% - 99.62%Forma y color:SolidPeso molecular:510.03Ref: TM-TQ0067
1mg74,00€5mg156,00€10mg227,00€25mg457,00€50mg655,00€100mg933,00€1mL*10mM (DMSO)167,00€CBP-IN-1
CAS:CBP-IN-1 (compound 12) acts as a potent CBP inhibitor exhibiting an IC50 of 1.5 nM and additionally suppresses CBP BRET and BRD4(1) with IC50 values of 690 nMFórmula:C27H33F2N7OPureza:98%Forma y color:SolidPeso molecular:509.59RBN-3143
CAS:RBN-3143: potent PARP14 inhibitor (IC50= 4 nM), blocks ADP-ribosylation, may treat lung inflammation.Fórmula:C22H28FN3O4SPureza:98.64%Forma y color:SoildPeso molecular:449.54Ref: TM-T67844
1mg95,00€5mg202,00€10mg298,00€25mg507,00€50mg730,00€100mg1.026,00€500mg2.052,00€1mL*10mM (DMSO)224,00€Vafidemstat
CAS:Vafidemstat (ORY-2001) is a lysine-histone demethylase (LSD1)/MAO-B inhibitor for the study of neurological disorders.Fórmula:C19H20N4O2Pureza:99.53%Forma y color:SolidPeso molecular:336.395-Methyl-2'-deoxycytidine
CAS:5-Methyl-2'-deoxycytidine (5MedCyd) is a pyrimidine nucleoside that when incorporated into single-stranded DNA can act in cis to signal de novo.Fórmula:C10H15N3O4Pureza:99.18% - 99.69%Forma y color:SolidPeso molecular:241.24LSD1-IN-20
CAS:LSD1-IN-20: Dual LSD1/G9a inhibitor, Ki 0.44/0.68 μM; hampers THP-1, MDA-MB-231 cell growth with IC50 0.51/1.60 μM at 72h.Fórmula:C27H38N6O2Pureza:98.21% - 98.72%Forma y color:SolidPeso molecular:478.63Phthalazinone pyrazole
CAS:Phthalazinone pyrazole: a potent, selective oral Aurora-A kinase inhibitor, overexpressed in tumors with oncogenic activity.Fórmula:C18H15N5OPureza:97.03%Forma y color:SolidPeso molecular:317.34Ref: TM-T21981
1mg64,00€2mg96,00€5mg145,00€10mg212,00€25mg353,00€50mg532,00€100mg792,00€200mg1.064,00€PROTAC BRD4-DCAF1 degrader-1
CAS:PROTACBRD4-DCAF1 degrader-1 (I-907) is a PROTAC degrader targeting BRD4-DCAF1, exhibiting a DC50 range of 10~100 nM.Fórmula:C60H64Cl2F2N8O9SForma y color:SolidPeso molecular:1182.17Talazoparib tosylate
CAS:PF-3882845 is an MR antagonist that binds to the progesterone receptor (PR) and is used in the study of endocrine disorders and urogenital disorders.Fórmula:C26H22F2N6O4SPureza:99.79%Forma y color:SolidPeso molecular:552.55Ref: TM-T16979
2mg42,00€5mg62,00€10mg88,00€25mg135,00€50mg188,00€100mg311,00€200mg432,00€1mL*10mM (DMSO)74,00€Ref: TM-T5S2358
1mg57,00€2mg81,00€5mg111,00€10mg160,00€25mg263,00€50mg378,00€100mg558,00€200mg797,00€1mL*10mM (DMSO)123,00€Aurora Kinases-IN-4
CAS:Aurora Kinases-IN-4 (Compound 11c) is a covalent, ATP-competitive inhibitor of aurora kinase A with an IC50 value of 1.7 nM.Fórmula:C26H28N8OPureza:98%Forma y color:SolidPeso molecular:468.55ZZM-1220
ZZM-1220, a covalent inhibitor of histone lysine methyltransferase G9a/GLP, exhibits IC50 values of 458 nM for G9a and 924 nM for GLP.Fórmula:C25H29N5O3Pureza:98%Forma y color:SolidPeso molecular:447.53
