Antimetabolito / análogo nucleósido
Los antimetabolitos y análogos de nucleósidos son compuestos que imitan a los nucleósidos naturales y se incorporan al ADN durante la replicación, lo que provoca la terminación de la cadena o la inhibición de la síntesis de ADN. Estos compuestos se utilizan ampliamente como agentes quimioterapéuticos en el tratamiento del cáncer y las infecciones virales. Al interrumpir la síntesis de ADN, los análogos de nucleósidos inducen el arresto del ciclo celular y la apoptosis. En CymitQuimica, ofrecemos una amplia gama de antimetabolitos y análogos de nucleósidos de alta calidad para apoyar su investigación en el tratamiento del cáncer, la terapia antiviral y la replicación del ADN.
Productos de "Antimetabolito / análogo nucleósido"
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2'-O-Methylinosine
CAS:2'-O-Methylinosine (2'-(o-Methyl)-inosine) is an orally bioavailable purine nucleoside analog with antihypertensive activity.Fórmula:C11H14N4O5Pureza:99.88%Forma y color:SolidPeso molecular:282.256-AZATHYMINE
CAS:6-azathymine inhibits D-3-aminoisobutyrate-pyruvate aminotransferase; 6-azauracil competes with beta-alanine, uncompetitive with pyruvic acid, Ki ~8.9 mM.Fórmula:C4H5N3O2Pureza:99.47%Forma y color:SolidPeso molecular:127.1Sangivamycin
CAS:Sangivamycin (NSC-65346) inhibits PKC (Ki=10μM) and hinders growth in various human cancers.Fórmula:C12H15N5O5Pureza:98.11%Forma y color:SolidPeso molecular:309.28Ref: TM-T9605
1mg126,00€5mg274,00€10mg416,00€25mg677,00€50mg944,00€100mg1.264,00€1mL*10mM (DMSO)360,00€5,6-Dihydro-5-methyluracil
CAS:5,6-Dihydro-5-methyluracil (Dihydrothymine) is an intermediate breakdown product of thymine.Fórmula:C5H8N2O2Pureza:98.53%Forma y color:SolidPeso molecular:128.13Decitabine
CAS:Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity.Fórmula:C8H12N4O4Pureza:98.06% - 99.87%Forma y color:Physical Description Fine White Crystalline Powder Used As A DrugPeso molecular:228.212',3'-Bis-(O-t-butyldimethylsilyl)uridine
CAS:2',3'-Bis-(O-t-butyldimethylsilyl)uridine is a nucleoside derivative protect the NH2/OH groups of nucleosides.inhibitory on viral replication,AIDS and herpes.Fórmula:C21H40N2O6Si2Pureza:99.88%Forma y color:SolidPeso molecular:472.72Ref: TM-TNU1182
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€200mg2.555,00€3-Deazauridine
CAS:3-Deazauridine (NSC-126849), a uridine analog, blocks CTP synthesis by competing with CTP synthetase.Fórmula:C10H13NO6Pureza:98.55%Forma y color:SolidPeso molecular:243.21GS-443902
CAS:Remdesivir triphosphate (GS-443902) inhibits RSV/HCV RdRp with IC50s: 1.1/5 µM.Fórmula:C12H16N5O13P3Pureza:98%Forma y color:SolidPeso molecular:531.25-BrdU
CAS:5-BrdU (Broxuridine) , a nucleoside analog, are used in the detection of proliferating cells and competes with thymidine for incorporation into DNA.Fórmula:C9H11BrN2O5Pureza:99.54% - 99.87%Forma y color:Crystals From Absolute Ethanol Physical Description White Crystalline Powder (Ntp 1992)Peso molecular:307.1Lobucavir
CAS:Lobucavir (BMS-180194; SQ 34514) is a nucleoside analogue and an antiviral agent with broad-spectrum activity against various viruses, including HBV, HIV/AIDS, and α, β, and γ herpesviruses (including CMV, herpes simplex virus, varicella-zoster virus, and Epstein-Barr virus).Fórmula:C11H15N5O3Forma y color:SolidPeso molecular:265.275-OHdU
CAS:5-OHdU (5-OHdU) is a major oxidation product of 2'-Deoxycytidine and can be incorporated into DNA in vitro.Fórmula:C9H12N2O6Pureza:98.32%Forma y color:SolidPeso molecular:244.2Ref: TM-T19152
1mg47,00€2mg60,00€5mg89,00€10mg131,00€25mg212,00€50mg316,00€100mg474,00€1mL*10mM (DMSO)90,00€Adenosine
CAS:Adenosine (D-Adenosine) is a ribonucleoside. Adenosine has vasodilatory, antiarrhythmic and analgesic effects. Cost-effective and quality-assured.Fórmula:C10H13N5O4Pureza:98.76% - 99.86%Forma y color:Needles (From Water +3/2) Physical Description White To Off-White Crystalline Powder (Ntp 1992)Peso molecular:267.24Deoxycytidine triphosphate trisodium salt
CAS:Deoxycytidine triphosphate trisodium salt (2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE TRISODI) contributes to antibiotic lethality in stationary-phase mycobacteria.Fórmula:C9H13N3Na3O13P3Pureza:99.80%Forma y color:SolidPeso molecular:533.1Trifluridine/tipiracil hydrochloride mixture
CAS:Trifluridine/tipiracil hydrochloride mixture (TAS-102) is a novel oral combination drug containing trifluridine (TFT) and Tipiracil hydrochloride (TTP) in aFórmula:C29H34Cl2F6N8O12Pureza:99.37% - ≥98%Forma y color:SolidPeso molecular:871.53Ref: TM-T3658
2mg39,00€5mg57,00€10mg87,00€25mg157,00€50mg250,00€100mg378,00€200mg568,00€500mg889,00€1mL*10mM (DMSO)78,00€Ac-rC Phosphoramidite
CAS:Ac-rC Phosphoramidite can modify phosphodisulfide oligonucleotides.Fórmula:C47H64N5O9PSiPureza:99.49%Forma y color:SolidPeso molecular:902.18-Azahypoxanthine
CAS:8-Azahypoxanthine (NSC-22709) inhibits hypoxanthine-guanine-xanthine phosphoribosyltransferase and has antimalarial properties.Fórmula:C4H3N5OPureza:≥98%Forma y color:Light Yellow To Light Beige Fine CrystallinePeso molecular:137.1Ref: TM-T20102
5mg48,00€10mg66,00€25mg104,00€50mg154,00€100mg216,00€200mg324,00€1mL*10mM (DMSO)48,00€Rabacfosadine
CAS:Rabacfosadine (GS-9219) is a novel prodrug of PMEG, an acyclic nucleotide phosphonate, with antitumor activity for the study of lymphoma.Fórmula:C21H35N8O6PPureza:98.75% - 99.43%Forma y color:SolidPeso molecular:526.535-Methylcytidine
CAS:5-Methylcytidine is a modified nucleoside derived from 5-methylcytosine and is a minor constituent of RNA as well as DNA for certain organisms.Fórmula:C10H15N3O5Pureza:99.02% - 99.88%Forma y color:SolidPeso molecular:257.242'-OMe-Guanosine
CAS:2'-OMe-Guanosine is a modified nucleoside produced by the action of tRNA guanosine-2'-o-methyltransferase. 2'-OMe-Guanosine has a certain pro-apoptotic effect.Fórmula:C11H15N5O5Pureza:98.92%Forma y color:White SolidPeso molecular:297.278-Chloroinosine
CAS:8-Chloroinosine is a purine nucleoside analog and a metabolite of the anticancer compound 8-chloro-adenosine.Fórmula:C10H11ClN4O5Pureza:99.37% - 99.56%Forma y color:SolidPeso molecular:302.67
