Reductasa
Las reductasas son una amplia clase de enzimas que catalizan la reducción de moléculas en diversas rutas bioquímicas. En endocrinología, reductasas específicas, como la 5α-reductasa, son cruciales para el metabolismo de las hormonas esteroides, incluida la conversión de testosterona en dihidrotestosterona (DHT). Los inhibidores de las enzimas reductasas se utilizan en el tratamiento de condiciones como la hiperplasia prostática benigna y la alopecia androgénica. En CymitQuimica, ofrecemos una variedad de inhibidores de reductasa de alta calidad para apoyar su investigación en la regulación hormonal, las vías metabólicas y el desarrollo terapéutico.
Productos de "Reductasa"
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Trimethoprim
CAS:Trimethoprim (NSC-106568) inhibits dihydrofolate reductase, CYP2C8, and OCT2 - an antibacterial agent.Fórmula:C14H18N4O3Pureza:99.80% - 99.81%Forma y color:White To Yellowish PowderPeso molecular:290.32COH29
CAS:COH29 is an oral RNR-blocking thiazole that may reduce DNA synthesis and promote apoptosis, with potential cancer-treating properties.Fórmula:C22H16N2O5SPureza:97.04% - 98.92%Forma y color:SolidPeso molecular:420.44Ref: TM-T3157
1mg37,00€2mg52,00€5mg79,00€10mg119,00€25mg217,00€50mg354,00€100mg590,00€1mL*10mM (DMSO)87,00€Alrestatin
CAS:Alrestatin (AY-22284) is a specific inhibitor of aldose reductase and attenuates glucose-induced angiotensin II production in rat vascular smooth muscle inFórmula:C14H9NO4Pureza:99.23%Forma y color:SolidPeso molecular:255.2256Ranirestat
CAS:Ranirestat (AS-3201) is an AR inhibitor with neuroprotective properties that improves peripheral nerve dysfunction in rats with advanced diabetic polyneuropathyFórmula:C17H11BrFN3O4Pureza:96.10% - 99.44%Forma y color:SolidPeso molecular:420.19Ref: TM-T16723
1mg79,00€5mg172,00€10mg264,00€25mg560,00€50mg898,00€100mg1.415,00€1mL*10mM (DMSO)182,00€Aurothiomalate sodium
CAS:Sodium aurothiomalate (Miochrysin) inhibits PKC-ι, TrxR; used as an anti-rheumatic and has anti-tumor properties.Fórmula:C4H3AuNa2O4SPureza:99.66%Forma y color:SoildPeso molecular:390.07Minalrestat
CAS:Minalrestat(ARI-509) is an orally active and potent aldose reductase inhibitor for the study of impaired microvascular reactivity in diabetic patients.Fórmula:C19H11BrF2N2O4Pureza:100% - 98.79%Forma y color:SolidPeso molecular:449.2Zopolrestat
CAS:Zopolrestat (CP 73850) is a potent inhibitor of aldose reductase (IC50 = 3.1 nM).Fórmula:C19H12F3N3O3SPureza:98.09%Forma y color:SolidPeso molecular:419.38Ref: TM-T35317
1mg35,00€2mg48,00€5mg70,00€10mg92,00€25mg202,00€50mg313,00€100mg465,00€1mL*10mM (DMSO)87,00€2-Chloro-1-(4-fluorobenzyl)benzimidazole
CAS:2-Chloro-1-(4-fluorobenzyl)benzimidazole is an inhibitor of aldose reductase (ALR2).Fórmula:C14H10ClFN2Pureza:99.64%Forma y color:SolidPeso molecular:260.69Methotrexate disodium
CAS:Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitorFórmula:C20H20N8Na2O5Pureza:99.77% - 99.96%Forma y color:SolidPeso molecular:498.4Quercetin 3-gentiobioside
CAS:Quercetin 3-gentiobioside from A. iwayomogi blocks AR and stops AGEs formation.Fórmula:C27H30O17Pureza:99.29% - 99.77%Forma y color:SolidPeso molecular:626.52Lidorestat
CAS:Lidorestat (IDD-676) is an aldose reductase inhibitor (IC50: 5 nM) with effective, selective and oral activity.Fórmula:C18H11F3N2O2SPureza:99.84%Forma y color:SolidPeso molecular:376.35Fidarestat
CAS:Fidarestat is an aldose reductase inhibitor (IC50s: 26 nM, 33 μM, and 1.8 μM for aldose reductase, AKR1B10, and V301L AKR1B10, respectively).Fórmula:C12H10FN3O4Pureza:98%Forma y color:SolidPeso molecular:279.22Methotrexate
CAS:Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.Fórmula:C20H22N8O5Pureza:96.84% - 99.46%Forma y color:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisPeso molecular:454.44Sulindac sulfone
CAS:Sulindac sulfone is a metabolite of the nonsteroidal anti-inflammatory drug sulindac. Sulindac sulfone is an inhibitor of aldose reductase (IC50 =367 nM).Fórmula:C20H17FO4SPureza:98.19% - 98.83%Forma y color:SolidPeso molecular:372.41Ref: TM-T23403
5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€200mg409,00€1mL*10mM (DMSO)55,00€Risarestat
CAS:Risarestat (CT-112) is a potent aldose reductase inhibitor and thyroid hormone receptor (TR) antagonist for the treatment of hypoglycemia.Fórmula:C16H21NO4SPureza:98.39%Forma y color:SolidPeso molecular:323.41(R)-Viloxazine Hydrochloride
CAS:(R)-Viloxazine Hydrochloride, the R-isomer of Viloxazine.Fórmula:C13H20ClNO3Pureza:99.29% - 99.48%Forma y color:SolidPeso molecular:273.76Ref: TM-T22413
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg472,00€100mg645,00€200mg868,00€1mL*10mM (DMSO)145,00€EBPC
CAS:EBPC is an inhibitor of aldose reductase.Fórmula:C14H15NO4Pureza:99.55%Forma y color:SolidPeso molecular:261.27Ref: TM-T22757
1mg57,00€2mg74,00€5mg104,00€10mg158,00€25mg275,00€50mg394,00€100mg560,00€200mg757,00€1mL*10mM (DMSO)117,00€Izonsteride
CAS:Izonsteride (LY320236) is a selective and potent 5alpha reductase inhibitor with dual action on the type I and type II isoforms of the enzyme.Izonsteride isFórmula:C24H26N2OS2Pureza:99.55%Forma y color:SolidPeso molecular:422.61MK 0434
CAS:MK 0434 is a steroid 5α-reductase inhibitor and hormone antagonist associated with a significant reduction in DHT.Fórmula:C25H31NO2Pureza:98.27% - 98.43%Forma y color:SolidPeso molecular:377.52AT-007
CAS:AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM).Fórmula:C17H10F3N3O3S2Pureza:99.36%Forma y color:SolidPeso molecular:425.4Ref: TM-T10393
1mg66,00€5mg111,00€10mg180,00€25mg329,00€50mg533,00€100mg743,00€1mL*10mM (DMSO)124,00€
