Receptor de glucocorticoides
El receptor de glucocorticoides (GR) es un receptor hormonal nuclear que media los efectos de los glucocorticoides, una clase de hormonas esteroides involucradas en la regulación del metabolismo, la respuesta inmunitaria y el estrés. Los agonistas y antagonistas del receptor de glucocorticoides se utilizan ampliamente en el tratamiento de enfermedades inflamatorias y autoinmunes, así como en la terapia contra el cáncer. Los moduladores de GR también son herramientas importantes para estudiar los roles fisiológicos y patológicos de los glucocorticoides. En CymitQuimica, ofrecemos una amplia gama de moduladores del receptor de glucocorticoides de alta calidad para apoyar su investigación en endocrinología, inmunología y regulación hormonal.
Productos de "Receptor de glucocorticoides"
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Medrysone
CAS:Medrysone is a synthetic glucocorticoid for topical use with anti-inflammatory and anti-allergic effects, altering gene expression to reduce inflammation.Fórmula:C22H32O3Pureza:97.72% - 99.91%Forma y color:SolidPeso molecular:344.49Prednisolone hemisuccinate
CAS:Prednisolone hemisuccinate is a soluble glucocorticoid and cortisol exerts anti-inflammatory, immunosuppressive, and antiallergic by binding to GR receptor.Fórmula:C25H32O8Pureza:99.96%Forma y color:SolidPeso molecular:460.52Dexamethasone acetate
CAS:Dexamethasone acetate (NSC 39471) is a potent anti-inflammatory steroid, blocks NF-kB, and lacks salt-retention.Fórmula:C24H31FO6Pureza:99.22% - 99.65%Forma y color:White Or Almost White Crystalline PowderPeso molecular:434.5GSK9027
CAS:GSK9027, a nonsteroidal GR agonist, is a partial 2×GRE reporter gene activator, less potent than dexamethasone.Fórmula:C27H19F4N3O2SPureza:99.36%Forma y color:SolidPeso molecular:525.52N-Demethyl Mifepristone
CAS:N-Demethyl Mifepristone (RU 42633), an active metabolite of Mifepristone, exhibits 61% of the affinity for the glucocorticoid receptor relative to Mifepristone'Fórmula:C28H33NO2Pureza:98%Forma y color:SolidPeso molecular:415.57Apararenone
CAS:Apararenone (MT-3995) is a receptor antagonist of mineralocorticoid receptor which can be used to treat non-alcoholic steatohepatitis and diabetic nephropathy.Fórmula:C17H17FN2O4SPureza:99.65%Forma y color:SolidPeso molecular:364.3922-Hydroxy mifepristone
CAS:22-Hydroxy Mifepristone (RU 42698) is an orally active hydroxylated alcohol metabolite that exhibits both anti-progestational and anti-glucocorticoid activities. This compound contains an alkyne group and is capable of undergoing copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing molecules. Furthermore, 22-Hydroxy Mifepristone demonstrates a relative binding affinity of 48% to the human glucocorticoid receptor.Fórmula:C29H35NO3Forma y color:SolidPeso molecular:445.59Prednisolone acetate
Prednisolone acetate (Omnipred) is the acetate salt form of prednisolone, a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Fórmula:C23H30O6Pureza:98.26% - 98.85%Forma y color:White Crystalline PowderPeso molecular:402.48Fluticasone furoate
CAS:Fluticasone furoate (Avamys), a potent, trifluorinated steroid with anti-inflammatory effects, treats allergic rhinitis.Fórmula:C27H29F3O6SPureza:99.58%Forma y color:SolidPeso molecular:538.58Ref: TM-T21404
4g2.663,00€5mg35,00€10mg52,00€25mg92,00€50mg137,00€100mg187,00€200mg279,00€500mg472,00€1mL*10mM (DMSO)58,00€Mifepristone
CAS:Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist.Fórmula:C29H35NO2Pureza:98.9% - ≥95%Forma y color:Pale Yellow SolidPeso molecular:429.59Fluocinolone (Acetonide)
CAS:Fluocinolone Acetonide (Flucort-N) is a glucocorticoid derivative used topically in the treatment of various skin disorders.Fórmula:C24H30F2O6Pureza:99.29% - 99.66%Forma y color:Crystals From Acetone & Hexane SolidPeso molecular:452.49Miricorilant
CAS:Miricorilant (CORT 118335) is a glucocorticoid receptor modulator for the study of digestive and metabolic disorders.Fórmula:C24H23F3N2O2Pureza:98.62%Forma y color:SolidPeso molecular:428.45Fludrocortisone acetate
CAS:Fludrocortisone acetate (9α-Fludrocortisone acetate) , a glucocorticoid-receptor agonist, binds to cytoplasmic receptors, translocates to the nucleus, andFórmula:C23H31FO6Pureza:96.92% - 98.03%Forma y color:Crystalline SolidPeso molecular:422.49Dexamethasone palmitate
CAS:DXP, a lipophilic prodrug of Dexamethasone, has 47x less glucocorticoid receptor affinity; it's an agonist & anti-inflammatory.Fórmula:C38H59FO6Pureza:98.08%Forma y color:SolidPeso molecular:630.87Triamcinolone hexacetonide
CAS:Triamcinolone hexacetonide, an exogenous synthetic corticosteroid, is a GR agonist used in the study of auto-reactive pericarditis and diabetic macular edema.Fórmula:C30H41FO7Pureza:99.57%Forma y color:SolidPeso molecular:532.64Amcinonide
CAS:Amcinonide (CL-34699) is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.Fórmula:C28H35FO7Pureza:98.33% - 99.62%Forma y color:SolidPeso molecular:502.57Budesonide
CAS:Budesonide (Pulmicort), an anti-inflammatory corticosteroid, has shown the effective glucocorticoid activitie and few mineralocorticoid activities. According to reports, Budesonide has extensively inhibitory effects against multiple cells types and mediators referred to allergic and nonallergic-mediated inflammatory. What's more, the anti-inflammatory action of budesonide has been revealed to contribute to the effectiveness of asthma.Fórmula:C25H34O6Pureza:99.03% - 99.72%Forma y color:Crystals SolidPeso molecular:430.53Cortisone acetate
CAS:Cortisone Acetate is a synthetic or semisynthetic analog of the naturally occurring cortisone hormone produced by the adrenal glands with anti-inflammatory andFórmula:C23H30O6Pureza:98.63% - 99.73%Forma y color:SolidPeso molecular:402.48Corticosterone
CAS:Corticosterone (Kendall's compound B) is an adrenocortical steroid with salocorticoid and glucocorticoid activity that is orally active.Fórmula:C21H30O4Pureza:97.25% - ≥95%Forma y color:SolidPeso molecular:346.46Prednisolone
CAS:Prednisolone (Hydroretrocortine) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties.Fórmula:C21H28O5Pureza:99.59% - 99.85%Forma y color:Crystals SolidPeso molecular:360.44
