Enzima

ST2/IL-1 RL1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

PTGES3 Protein, Human, Recombinant (E. coli, His) is expressed in E. coli.

α-Arbutin (4-hydroxyphenyl-D-lucopyranoside) is a synthetic and functional active ingredient for skin lightening.

Human Esterase D is a cytoplasmic serine hydrolase that belongs to the esterase D family.

AMPK (G1/B1/A2) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

Catalyzes the reverse reaction of octopine dehydrogenation.

HAAO Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag.

Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.

Lipase 70 recombinantly expressed in E. coli comes in a spray-dried formulation. It has its pH optimum at 6-8 and temp. optimum at 35-45°C. Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces catalyzing hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications. Lipase 70 was shown to hydrolyze p-Nitrophenyl esters of butyrate (100 % activity), octanoate (62 %), laurate (15 %), palmitate (4 %), stearate (3 %), arachidate (2 %) and behenate (0.2 %).

Ribonuclease H1 Protein, Human, Recombinant (His) is expressed in E. coli.

Creatine kinase M/CKM Protein, Human, Recombinant is expressed in E. coli.

Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.

Essential for bone resorption and osteoclast differentiation.

Aldehyde dehydrogenase 1 family member A2 (ALDH1A2), also known as retinaldehyde dehydrogenase 2 (RALDH2), belongs to the aldehyde dehydrogenase family which

The main protease Mpro is a key protein in the lifecycle of the SARS-CoV-2 virus. Mpro cleaves the viral polyproteins at the C-terminal end of a glutamine residue in recognition sequences containing Leu-Gln-(Ser, Ala, Gly) motifs (Rut et al, 2020).  As SARS-CoV-2 MPro has no closely related homologues in humans, it represents an attractive drug target (Ullrich and Nitsche, 2020). In summary, the Mpro protease is a chymotrypsin-like cysteine protease, requires homodimerisation for proteolytic activity, cleaves the viral polyproteins in 11 distinct sites, exclusively after a glutamine residue. A fluorogenic substrate for Mpro assays is Ac-Abu-Tle-Leu-Gln-AMC.The protein amount or better its concentration in solution is quantified using either A280 (absorption at 280 nm with its specific absorption coefficient) or using the Bradford assay (uses the dye Coomassie Brilliant Blue). Both of these methods quantify the total amount of protein in a sample, no matter what the oligomerization state is.

Beta-D-glucuronidase from E.coli is a  highly specific enzyme in hydrolyzing glucuronides.

LasA Protein, Pseudomonas aeruginosa, Recombinant (His & SUMO) is expressed in E.

SARM1 Protein, Human, Recombinant (His & KSI) is expressed in E.

Dual specificity tyrosine-phosphorylation-regulated kinase 3, also known as Regulatory erythroid kinase, REDK and DYRK3, is a nucleus protein which belongs to

Plays a key role in glycolysis and gluconeogenesis.

Catalyzes the oxidation of methanol to yield formaldehyde.

ENTPD3 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag.

Triose-phosphate isomerase (TPI, TIM; EC 5.3.1.1) is an enzyme that catalyzes the reversible isomerisation of dihydroxyacetone phosphate and D-glyceraldehyde 3-phosphate:  DHAP ⇌ GADP  The reaction mechanism involves the formation of an enediol intermediate. One unit of Triose-phosphate isomerase will convert 1.0 μmole glyceraldehyde 3-phosphate to dihydroxyacetone phosphate per min at pH 7.6 and 25 °C.

Benzolamide (CL 11366) inhibits carbonic anhydrase effectively and low-threshold calcium currents in hippocampal pyramidal neurons.

RIZ1 Protein, Human, Recombinant (GST) is expressed in E.

Tissue-type plasminogen activator (PLAT) is a protein that secreted into extracellular space.

2-Hydroxy-4-methoxybenzaldehyde (4-Methoxysalicylaldehyde) is an isomer of Vanillin, and a potent tyrosinase inhibitor, could be used to synthesis Urolithin M7.

In the presence of other necessary color factors, this glycosylation reaction allows the accumulation of anthocyanin pigments.

Exostosin-like 2 (EXTL2) is a member of the exostosin (EXT)-related family which contains five members: EXT1, EXT2, EXTL1, EXTL2, and EXTL3.

α-Glucosidase (EC 3.2.1.20) is a glycoside hydrolase enzyme that hydrolyzes α-1,4-linked D-glucose residues (e.g. in starch or oligosaccharides)  to produce α-D-glucose. One unit of α-Glucosidase will release 1.0 µmole of p-nitrophenol from the chromogenic substrate mimic 4-nitrophenyl α-D-glucopyranoside per minute at pH 6.8 and 37 °C.

A cytochrome P450 monooxygenase that plays a major role in adrenal steroidogenesis.

The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete.

Creatinase (EC 3.5.3.3) is an enzyme that catalyzes the fellowing reaction: creatine + H2O ⇌ sarcosine + ureaOne unit of creatinase will hydrolyze 1.0 µmole of creatine into sarcosine and urea per min at pH 7.5 and 37 °C.

ABHD11 Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q8NFV4.

Lyn Protein, Mouse, Recombinant (His & Myc) is expressed in E.

Alkaline Phosphatase/ALPL Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.

S1 is an NAD-dependent ADP-ribosyltransferase, which plays a crucial role in the pathogenesis of B.pertussis causing disruption of normal host cellular

Lipases belong to the family of esterases and naturally act on triglycerides at lipid-water interfaces. Lipases/esterases can be used as versatile tools in hydrolytic reactions, esterifications and transesterification reactions in industrial and food applications.

DDR2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 Cells. The accession number is Q16832.

Alteplase is human plasminogen activator (EC 3.4.21.68, that cleaves plasminogen into enzymatically active form, plasmin), recombinantly expressed in CHO cells. Alteplase belongs to the group of thrombolytic agents, and it has shown to be effective in restoring blood flow by breaking down clots.

Removes the formyl group from the N-terminal Met of newly synthesized proteins.

Critical role in recombination and DNA repair.

MAST4 Protein, Human, Recombinant (His & Myc) is expressed in E. coli.

GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis.

ST2/IL-1 RL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.

LRRK2 Protein, Human, Recombinant (His) is expressed in E. coli with C-6xHis. The accession number is Q5S007.