Nrf2
Nrf2 es un factor de transcripción que regula la expresión de proteínas antioxidantes y enzimas de desintoxicación, desempeñando un papel crucial en la defensa celular contra el estrés oxidativo y la inflamación. La activación de la señalización de Nrf2 proporciona protección contra diversas enfermedades, incluyendo el cáncer, la neurodegeneración y los trastornos cardiovasculares. Los moduladores de Nrf2 están siendo explorados por su potencial en aplicaciones terapéuticas para reducir el daño oxidativo y la inflamación. En CymitQuimica, ofrecemos una gama de moduladores de la vía Nrf2 de alta calidad para apoyar su investigación en estrés oxidativo, inflamación y prevención de enfermedades.
Productos de "Nrf2"
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Brusatol
CAS:Brusatol (NSC-172924) is a natural product isolated from the Brucea javanica plant. It inhibits Nrf2.Fórmula:C26H32O11Pureza:99.35% - 99.82%Forma y color:SolidPeso molecular:520.53Ref: TM-TQ0211
1mg39,00€5mg94,00€10mg160,00€25mg311,00€50mg502,00€100mg715,00€200mg938,00€1mL*10mM (DMSO)107,00€DDO-7263
CAS:DDO-7263, a 1,2,4-Oxadiazole, boosts Nrf2 by binding Rpn6, blocking 26S proteasome assembly, and has anti-inflammatory effects.Fórmula:C14H9F2N3OPureza:99.75%Forma y color:SolidPeso molecular:273.24Nrf2-IN-3
CAS:Nrf2-IN-3 is an NRF2 inhibitor that selectively sensitizes xenografts of mouse mKEAP1 cancer cells to cisplatin.Fórmula:C22H26N4O4SPureza:98.07%Forma y color:SolidPeso molecular:442.53Ref: TM-T78841
1mg65,00€5mg139,00€10mg217,00€25mg411,00€50mg658,00€100mg1.035,00€200mg1.396,00€1mL*10mM (DMSO)154,00€4-P-PDOT
CAS:4-P-PDOT (4-phenyl-2- propionamidotetralin) is a potent, selective and affinity Melatonin receptor (MT2) antagonist.Fórmula:C19H21NOPureza:99.68%Forma y color:SolidPeso molecular:279.38Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851)
Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) is an antibody targeting Phospho-NFE2L2 (Ser40). Anti-Phospho-NFE2L2 (Ser40) Antibody (6V851) can be used in ELISA, WB, IHC, IF.Forma y color:Odour Liquid(E)-[6]-Dehydroparadol
CAS:(E)-[6]-Dehydroparadol ((6)-Dehydroparadol), an oxidative metabolite of [6]-Shogaol, is a potent Nrf2 activator.Fórmula:C17H24O3Pureza:99.87%Forma y color:SolidPeso molecular:276.37Ref: TM-T13436
1mg44,00€5mg93,00€10mg116,00€25mg207,00€50mg283,00€100mg406,00€500mg919,00€1mL*10mM (DMSO)93,00€AEM1
CAS:AEM1 is an inhibitor of deregulated NRF2 transcriptional activity in cancer.Fórmula:C20H14FN3O2SPureza:98.37%Forma y color:SolidPeso molecular:379.41Ref: TM-T8979
2mg38,00€5mg51,00€10mg92,00€25mg170,00€50mg298,00€100mg510,00€200mg737,00€1mL*10mM (DMSO)60,00€Nrf2-IN-1
CAS:Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).Fórmula:C21H22ClN3O2Pureza:95.00% - 99.68%Forma y color:SolidPeso molecular:383.87Ref: TM-T12253
1mg78,00€5mg169,00€10mg230,00€25mg383,00€50mg537,00€100mg748,00€200mg1.035,00€1mL*10mM (DMSO)301,00€AA147
CAS:AA147 is an ER proteostasis regulator that selectively activates the ATF6 arm of UPR as a prodrug.Fórmula:C16H17NO2Pureza:99.24%Forma y color:SolidPeso molecular:255.31Ref: TM-T14080
5mg63,00€10mg96,00€25mg178,00€50mg265,00€100mg395,00€500mg894,00€1mL*10mM (DMSO)69,00€Anti-NFE2L2 Antibody (6K859)
Anti-NFE2L2 Antibody (6K859) is an antibody targeting NFE2L2. Anti-NFE2L2 Antibody (6K859) can be used in ELISA, IF.Forma y color:Odour LiquidK67
CAS:K67 competitively inhibits the interaction between Nrf2-ETGE and Keap1 and can be used to study cancer.Fórmula:C29H30N2O7S2Pureza:98.43%Forma y color:SolidPeso molecular:582.69Eriodictyol-7-O-glucoside
CAS:Eriodictyol-7-O-glucoside, a flavonoid in pistachio skin, activates Nrf2 and protects against Cisplatin toxicity.Fórmula:C21H22O11Pureza:99.53%Forma y color:SolidPeso molecular:450.39Trilobatin
CAS:Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFórmula:C21H24O10Pureza:97.16%Forma y color:SolidPeso molecular:436.41Ref: TM-T2S0731
1mg64,00€5mg124,00€10mg165,00€25mg323,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)137,00€Artemisitene
CAS:Artemisitene, an oxidized antimalarial derivative of Artemisinin, stems from precursors like Artemisinin B and Artemisinic acid.Fórmula:C15H20O5Pureza:99.58%Forma y color:SolidPeso molecular:280.32Ref: TM-T21065
1mg95,00€5mg187,00€10mg329,00€25mg560,00€50mg800,00€100mg1.103,00€1mL*10mM (DMSO)281,00€I-152
CAS:Bepranemab (UCB 0107) is a humanized IgG monoclonal antibody against tau for the study of Alzheimer's disease (AD) and tau proteinopathies.Fórmula:C9H16N2O3S2Pureza:98.36%Forma y color:SolidPeso molecular:264.37
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