Bomba de protones
Las bombas de protones son proteínas de membrana que transportan activamente protones (H+) a través de la membrana celular o de las membranas de los orgánulos, creando un gradiente de protones que es esencial para varios procesos celulares. La bomba de protones más conocida es la H+/K+ ATPasa, que se encuentra en el revestimiento del estómago y es responsable de la secreción de ácido. Las bombas de protones también son fundamentales en la respiración celular y la regulación del pH. La disfunción de la actividad de las bombas de protones está asociada con condiciones como el reflujo ácido, las úlceras y la acidosis metabólica. En CymitQuimica, ofrecemos una selección de inhibidores y moduladores de bombas de protones para apoyar su investigación en gastroenterología, metabolismo y bioenergética celular.
Productos de "Bomba de protones"
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Bafilomycin A1
CAS:Bafilomycin A1 belongs to the macrolide class of antibiotics and is a V-ATPase (IC50=0.44 nM) that is specific and reversible.Fórmula:C35H58O9Pureza:95.87% - 99.36%Forma y color:SolidPeso molecular:622.83Diphyllin
CAS:Diphyllin could be characterized as a new V-ATPase inhibitor in treating gastric cancer and inhibiting the phosphorylation of LRP6 in Wnt/β-catenin signaling.Fórmula:C21H16O7Pureza:99.91% - 99.98%Forma y color:SolidPeso molecular:380.35Pantoprazole sodium
CAS:Pantoprazole sodium is a proton pump inhibitor that irreversibly blocks gastric acid secretion by bonding with H+/K+-ATPase.Fórmula:C16H14F2N3NaO4SPureza:96.92% - 99.81%Forma y color:White To Off-White SolidPeso molecular:405.35V-ATPase-IN-1
CAS:V-ATPase-IN-1 (Compound 3b-03) is an inhibitor of Vacuolar-type H+-ATPases (V-ATPase), exhibiting an inhibition constant (IC50) of 194.80 μM and effectively targeting the V-ATPase subunit A with a dissociation constant (Kd) of 0.803 μM. This compound demonstrates insecticidal activity against M. separata (LC50 = 2.64 mM), aiding in the development of chemical insecticides.Fórmula:C21H20ClNO2Forma y color:SolidPeso molecular:353.84Linaprazan
CAS:Linaprazan (AZD0865) inhibits gastric H+,K+-ATPase by K+-competitive binding with an IC50 of 1.0 μM.Fórmula:C21H26N4O2Pureza:99.63%Forma y color:SolidPeso molecular:366.46Rabeprazole Sulfide
CAS:Rabeprazole Sulfide (Rabeprazole Related Compound E) is an antiulcer drug in the class of proton pump inhibitors.Fórmula:C18H21N3O2SPureza:99.34% - 99.80%Forma y color:Off-White Crystalline PowderPeso molecular:343.44Zinc pyrithione
CAS:Zinc pyrithione (OM-1563), an antibacterial and antifungal agent can disrupt membrane transport by blocking the proton pump.Fórmula:C10H8N2O2S2ZnPureza:99.47% - 99.64%Forma y color:Off-White To Tan PowderPeso molecular:317.71Ilaprazole sodium hydrate
CAS:Ilaprazole sodium hydrate (IY-81149 sodium hydrate) is a proton pump inhibitor that blocks the transport of HSV particles.Fórmula:C19H21N4NaO4SPureza:99.2%Forma y color:SolidPeso molecular:424.45ATP4A Protein, Human, Recombinant (His & Myc)
ATP4A Protein, Human, Recombinant (His & Myc) is expressed in E.Forma y color:Lyophilized PowderPeso molecular:54.6 kDa (predicted)Omeprazole
CAS:Omeprazole (Losec) is a proton pump inhibitor (PPI), Omeprazole(Losec) is a potent brain penetrant neutral sphingomyelinase (N-SMase) inhibitor.Fórmula:C17H19N3O3SPureza:98.43% - 98.48%Forma y color:White SolidPeso molecular:345.42Esomeprazole Sodium
CAS:Esomeprazole Sodium ((S)-Omeprazole sodium) is the S-isomer of omeprazole with selective and irreversible proton pump inhibitor activity.Fórmula:C17H18N3O3S·NaPureza:100% - 98.17%Forma y color:SolidPeso molecular:367.4Pumaprazole
CAS:Pumaprazole (BY-841) is an antagonist of a reversible proton pump.Fórmula:C19H22N4O2Pureza:99.6%Forma y color:SolidPeso molecular:338.4Ref: TM-T16682
1mg92,00€5mg188,00€10mg311,00€25mg635,00€50mg1.017,00€100mg1.644,00€200mg2.213,00€1mL*10mM (DMSO)215,00€Ilaprazole sodium
CAS:Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor.Fórmula:C19H17N4NaO2SPureza:99.06%Forma y color:SolidPeso molecular:388.42Ref: TM-T1756
1mg37,00€2mg52,00€5mg77,00€10mg92,00€25mg188,00€50mg305,00€100mg487,00€1mL*10mM (DMSO)79,00€Levolansoprazole
CAS:Levolansoprazole ((S)-Lansoprazole), a proton pump inhibitor, irreversibly inhibits H+/K+-stimulated ATPase pumps in parietal cells (IC50: 5.2 μM).Fórmula:C16H14F3N3O2SPureza:98.62%Forma y color:SolidPeso molecular:369.36Ref: TM-T20714
1mg135,00€2mg188,00€5mg329,00€10mg467,00€25mg677,00€50mg929,00€100mg1.244,00€200mg1.681,00€1mL*10mM (DMSO)331,00€Esomeprazole Magnesium trihydrate
CAS:Esomeprazole Magnesium trihydrate ((S)-Omeprazole magnesium trihydrate) is a proton pump inhibitor indicated for the short-term treatment of gastroesophagealFórmula:C34H42MgN6O9S2Pureza:98.52%Forma y color:Off-White PowderPeso molecular:767.17Bamaquimast
CAS:Bamaquimast (L 0042) is a proton pump inhibitor for the study of asthma-like immune system disorders and respiratory diseases.Fórmula:C16H21N3O3Pureza:98.40%Forma y color:SolidPeso molecular:303.36WY-47766
CAS:WY-47766, a proton pump inhibitor, is used potentially for the treatment of postmenopausal osteoporosis.Fórmula:C14H13N3O2SPureza:98.11% - 99.75%Forma y color:SolidPeso molecular:287.34Vonoprazan
CAS:Vonoprazan (TAK-438 (free base)) is an orally active potassium-competitive acid blocker.Vonoprazan can be used for the treatment of gastroduodenal ulcer andFórmula:C17H16FN3O2SPureza:99.92%Forma y color:SolidPeso molecular:345.39Esomeprazole
CAS:Esomeprazole is the S-isomer of omeprazole, inhibits the lysosomal cysteine protease legumain to prevent cancer metastasis.Fórmula:C17H19N3O3SPureza:98.20%Forma y color:SolidPeso molecular:345.42Pantoprazole
CAS:Pantoprazole (BY1023) is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal refluxFórmula:C16H15F2N3O4SPureza:99.28% - 99.63%Forma y color:Almost White SolidPeso molecular:383.37
