Receptor CGRP
Los receptores de CGRP están involucrados en la transmisión del dolor y la regulación del flujo sanguíneo. El CGRP es un neuropéptido que desempeña un papel crucial en la fisiopatología de la migraña al dilatar los vasos sanguíneos y modular las vías de señalización del dolor. Dirigirse a los receptores de CGRP se ha convertido en un enfoque prometedor en el desarrollo de terapias para la migraña. En CymitQuimica, ofrecemos una gama de moduladores de receptores de CGRP para apoyar su investigación en el manejo del dolor, neurobiología y salud vascular.
Productos de "Receptor CGRP"
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Hay 16 productos en esta categoría.
CGRP antagonist 6
CGRP Antagonist 6 (Compound 23) is a potent CGRP receptor antagonist (Ki: 0.84 nM). It is utilized in the study of migraines.Forma y color:Odour SolidVazegepant hydrochloride
CAS:Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.Fórmula:C36H47ClN8O3Pureza:98.93%Forma y color:SolidPeso molecular:675.3Ref: TM-T8682
1mg107,00€5mg227,00€10mg334,00€25mg565,00€50mg805,00€100mg1.111,00€1mL*10mM (DMSO)329,00€β-CGRP, human acetate
β-CGRP, human acetate is one of calcitonin peptides and acts via the complex of receptor-activity-modifying protein (RAMP) and calcitonin-receptor-like receptorFórmula:C164H271N51O50S3Pureza:99.35%Forma y color:SolidPeso molecular:3853.46Vazegepant
CAS:Vazegepant is an intranasal CGRP receptor antagonist utilized for conducting acute migraine research.Fórmula:C36H46N8O3Pureza:98.61%Forma y color:SolidPeso molecular:638.80Calcitonin-13C6,15N4 TFA
Calcitonin-13CIC6,15NIC4(salmon) (Salmon calcitonin-13CIC6,15NIC4) TFA is a version of calcitonin(salmon) labeled with carbon-13 and nitrogen-15. This hormone regulates calcium and acts dualistically as an agonist to both amylin and calcitonin receptors, promoting bone formation while inhibiting bone resorption.Fórmula:C1401C5H240N4315NO48S2·5C2HF3O2Forma y color:SolidPeso molecular:4007.93Telcagepant
CAS:Telcagepant (MK-0974) is an oral calcitonin gene-related peptide receptor (CGRP) antagonist that blocks CGRP receptors, migraines and for pain relief.Fórmula:C26H27F5N6O3Pureza:98.98%Forma y color:SolidPeso molecular:566.52Atogepant
CAS:Atogepant (MK-8031) is an orally available, selective and potent calcitonin gene-related peptide receptor (CGRP) antagonist for the study of migraine.Fórmula:C29H23F6N5O3Pureza:99.66%Forma y color:SolidPeso molecular:603.52Ref: TM-T26682
1mg156,00€5mg264,00€10mg329,00€25mg655,00€50mg1.169,00€100mg1.700,00€200mg2.300,00€1mL*10mM (DMSO)354,00€MK-3207 Hydrochloride
CAS:MK-3207 Hydrochloride (MK-3207 HCl) is a potent CGRP receptor antagonist with IC50 and Kiof 0.12 nM and 0.022 nM, highly selective versus human AM1, AM2, CTR, and AMY3. Phase 2.Fórmula:C31H30ClF2N5O3Pureza:98%Forma y color:SolidPeso molecular:594.05Olcegepant
CAS:Olcegepant (BIBN-4096) is an effective and selective non-peptide calcitonin gene-related peptide 1 (CGRP1) receptor antagonist (IC50 of 0.03 nM and Ki of 14.4Fórmula:C38H47Br2N9O5Pureza:96.08%Forma y color:SolidPeso molecular:869.65ML230
CAS:ML230 is a selective ATP-binding cassette (ABC) transporter ABCG2 inhibitor.Fórmula:C25H21N5O3Pureza:98%Forma y color:SolidPeso molecular:439.47Rimegepant
CAS:View and buy Rimegepant from TargetMol.BMS-927711 is a highly potent, oral calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki value of 0.027 nM.Cited in 1 publications.Fórmula:C28H28F2N6O3Pureza:99.1% - 99.8%Forma y color:SolidPeso molecular:534.56Calcitonin (salmon)
CAS:Calcitonin (salmon), a calcium regulating hormone, is used to treat osteoporosis in women who are at least 5 years past menopause.Fórmula:C145H240N44O48S2Pureza:99.41% - 99.80%Forma y color:PowderPeso molecular:3431.85Ubrogepant
CAS:Ubrogepant (MK-1602) is an antagonist of calcitonin gene-related peptide receptor that can be used in the acute treatment of migraine studies.Fórmula:C29H26F3N5O3Pureza:99.79%Forma y color:SolidPeso molecular:549.54Ref: TM-T17194
1mg153,00€5mg378,00€10mg597,00€25mg929,00€50mg1.225,00€100mg1.681,00€1mL*10mM (DMSO)487,00€Erenumab
CAS:Erenumab: human antibody blocking CGRP receptors to prevent migraines.Pureza:99.43% (SEC-HPLC) - > 95%Forma y color:LiquidPeso molecular:146.2 kDaSUN B8155
CAS:SUN B8155 is a CT receptor agonist that induces cAMP formation in cells expressing recombinant human CT receptor.Fórmula:C14H15N3O3Pureza:99.38% - 99.38%Forma y color:SolidPeso molecular:273.29Galcanezumab
CAS:Galcanezumab: humanized IgG4 antibody that targets CGRP for migraine and cluster headache prevention/treatment.Pureza:> 95%Forma y color:LiquidPeso molecular:144.08 kDa
