OAT
Los transportadores de aniones orgánicos son una familia de proteínas de membrana que median la captación y excreción de varios aniones orgánicos endógenos y exógenos, incluyendo medicamentos, toxinas y subproductos metabólicos. Los OAT se expresan principalmente en los riñones y el hígado, donde juegan un papel crucial en la desintoxicación y la eliminación de medicamentos. La disfunción de la función de los OAT puede llevar a toxicidad por medicamentos y trastornos renales. En CymitQuimica, ofrecemos una variedad de moduladores de OAT para apoyar su investigación en farmacología, toxicología y función renal.
Productos de "OAT"
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Hay 14 productos en esta categoría.
Puliginurad
CAS:Puliginurad (YL-90148) is a urate transporter protein inhibitor that inhibits the reabsorption of uric acid.Puliginurad is used in the treatment of gout.Fórmula:C19H16N2O2SPureza:99.96% - 99.96%Forma y color:SolidPeso molecular:336.41Verinurad
CAS:Verinurad (RDEA3170) (RDEA3170) is an organic anion transporter URAT1 (SLC22A12) inhibitor for the treatment of gout and hyperuricemia.Fórmula:C20H16N2O2SPureza:97.36% - 99.22%Forma y color:SolidPeso molecular:348.42Benzarone
CAS:Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.Fórmula:C17H14O3Pureza:99.33%Forma y color:SolidPeso molecular:266.29URAT1 inhibitor 1
CAS:URAT1 inhibitor 1 (1g) is an inhibitor of uric acid transporter 1 (URAT1) (IC50: 32 nM), has the potential to treat hyperuricemia associated with gout.Fórmula:C19H15Br2N5O2S2Pureza:98%Forma y color:SolidPeso molecular:569.29Epaminurad HCl
CAS:Epaminurad HCl is a URAT1 inhibitor with partial inhibition of OAT1 and OAT3 (organic anion transporters).Epaminurad HCl is a pro-uric acid excretory agent used for the prevention and treatment of gout and hyperuricemia.Fórmula:C14H11Br2ClN2O3Pureza:100% - 99.01%Forma y color:SoildPeso molecular:450.51Ref: TM-T27275L
1mg124,00€5mg298,00€10mg487,00€25mg778,00€50mg1.026,00€100mg1.415,00€1mL*10mM (DMSO)328,00€Lesinurad
CAS:Lesinurad (RDEA594), a selective uric acid reabsorption inhibitor, is used to treat gout without causing liver damage.Fórmula:C17H14BrN3O2SPureza:99.83% - 99.86%Forma y color:SolidPeso molecular:404.28Ref: TM-T6875
10mg47,00€25mg85,00€50mg133,00€100mg208,00€200mg310,00€500mg520,00€1mL*10mM (DMSO)35,00€Cyazofamid
CAS:Cyazofamid functions as a fungicide by impairing the production of ATP. It inhibits Organic Cation Transporter 3 (OCT3) and OAT1 with IC50 values of 1.54 and 17.3 μM, respectively.Fórmula:C13H13ClN4O2SForma y color:SolidPeso molecular:324.79Lesinurad sodium
CAS:Lesinurad sodium (RDEA594 sodium) is a selective inhibitor of uric acid reabsorption and is used in the study of cardiovascular diseases.Fórmula:C17H13BrN3NaO2SPureza:99.97%Forma y color:SolidPeso molecular:426.265-Fluoromethylornithine dihydrochloride
CAS:5-Fluoromethylornithine dihydrochloride (5-FMOrn dihydrochloride) is an OAT inhibitor and OAT inactivator, which can be used to study metabolic diseases.Fórmula:C6H15Cl2FN2O2Pureza:90%Forma y color:SolidPeso molecular:237.1Dotinurad
CAS:Dotinurad ((3,5-dichloro-4-hydroxyphenyl)(1,1-dioxidobenzo[d]thiazol-3(2H)-yl)methanone) is a potent agent of uricosuric (IC50: 3.6 μM for uric acid).Fórmula:C14H9Cl2NO4SPureza:97.43% - 98.95%Forma y color:SolidPeso molecular:358.2Ref: TM-T15160
1mg130,00€5mg305,00€10mg472,00€25mg778,00€50mg1.035,00€100mg1.415,00€1mL*10mM (DMSO)240,00€Fraxin
CAS:Fraxin (Fraxoside) is a glucoside of fraxetin.Fórmula:C16H18O10Pureza:99.19% - 99.87%Forma y color:Yellow PowderPeso molecular:370.31Ref: TM-T3783
1mg38,00€5mg79,00€10mg119,00€25mg221,00€50mg313,00€100mg470,00€200mg657,00€1mL*10mM (DMSO)87,00€Indican
CAS:Indican (Indoxyl-β-D-glucoside) is a natural protective compound that is used to protect the liver.Fórmula:C14H17NO6Pureza:99.92% - ≥98%Forma y color:White To Off-White Crystalline PowderPeso molecular:295.29Lingdolinurad
CAS:Lingdolinurad is a uric acid transporter protein inhibitor targeting hURAT1 for the study of hyperuricemia or gout.Fórmula:C17H12BrN3O2Pureza:98.70%Forma y color:SolidPeso molecular:370.2Ref: TM-T79854
1mg185,00€5mg459,00€10mg657,00€25mg1.026,00€50mg1.415,00€100mg1.872,00€1mL*10mM (DMSO)469,00€Cabotegravir
CAS:Cabotegravir (S/GSK1265744) (GSK744, GSK1265744) is a long-acting HIV integrase inhibitor and inhibits the HIV-1 integrase catalyzed strand transfer reaction (Fórmula:C19H17F2N3O5Pureza:98.55% - 99.92%Forma y color:SolidPeso molecular:405.35
