PDE
Las fosfodiesterasas (PDEs) son enzimas que hidrolizan nucleótidos cíclicos, como el AMPc y el GMPc, en sus formas inactivas, desempeñando un papel clave en la regulación de las vías de señalización intracelular. Los inhibidores de PDE se utilizan en el tratamiento de diversas afecciones, como enfermedades cardiovasculares, disfunción eréctil y trastornos respiratorios, debido a su capacidad para modular los niveles de nucleótidos cíclicos. En CymitQuimica, ofrecemos una gama de inhibidores de PDE para apoyar su investigación en señalización celular, farmacología y desarrollo terapéutico.
Productos de "PDE"
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Propentofylline
CAS:Propentofylline (Hextol) has neuroprotective, antiproliferative and anti-inflammatory activities and can be used in the study of Alzheimer's disease.Fórmula:C15H22N4O3Pureza:99.11% - 99.42%Forma y color:Off-White SolidPeso molecular:306.36Ref: TM-T19812
1mg69,00€5mg145,00€10mg212,00€25mg358,00€50mg527,00€100mg750,00€1mL*10mM (DMSO)157,00€cis-Tadalafil
CAS:Tadalafil: a carboline-based PDE5 inhibitor, treats erectile dysfunction, prostatic hyperplasia, and pulmonary hypertension.Fórmula:C22H19N3O4Pureza:≥98%Forma y color:SolidPeso molecular:389.4Anti-ALDH7A1 Antibody (3P955)
Anti-ALDH7A1 Antibody (3P955) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (3P955) can be used in WB,ELISA,IP.Forma y color:Odour LiquidThioquinapiperifil dihydrochloride
CAS:Thioquinapiperifil dihydrochloride is a potent, selective PDE-5 inhibitor (IC50: 0.074 nM) for research.Fórmula:C24H29ClN6OSPureza:98.73%Forma y color:SolidPeso molecular:485.05Ref: TM-T9773
1mg84,00€5mg178,00€10mg266,00€25mg434,00€50mg562,00€100mg787,00€200mg1.035,00€1mL*10mM (DMSO)205,00€Homo Sildenafil
CAS:Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.Fórmula:C23H32N6O4SPureza:99.88%Forma y color:White SolidPeso molecular:488.6Ref: TM-T8919
2mg42,00€5mg64,00€10mg92,00€25mg187,00€50mg281,00€100mg393,00€200mg552,00€1mL*10mM (DMSO)78,00€Ketotifen fumarate
CAS:Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators.Fórmula:C23H23NO5SPureza:99.25% - 99.73%Forma y color:SolidPeso molecular:425.5Mardepodect
CAS:Mardepodect (PF-2545920) is a phosphodiesterase inhibitor selective for the PDE10A subtype with an IC50 of 0.37 nM, >1000-fold selectivity over PDE.Fórmula:C25H20N4OPureza:98.82% - 99.81%Forma y color:SolidPeso molecular:392.45Ref: TM-T16499
1mg43,00€2mg55,00€5mg92,00€10mg150,00€25mg245,00€50mg365,00€100mg547,00€1mL*10mM (DMSO)92,00€Lirimilast
CAS:Lirimilast: oral PDE4 inhibitor (IC50: 49 nM), anti-inflammatory, treats asthma/COPD.Fórmula:C17H12Cl2N2O6SPureza:98%Forma y color:SolidPeso molecular:443.26PDE10-IN-1
CAS:PDE10-IN-1 (SEP-0372814) is used for treating CNS and metabolic disorders.Fórmula:C21H19N7Pureza:99.65%Forma y color:SolidPeso molecular:369.42N-Methylbenzamide
CAS:N-Methylbenzamide is a potent phosphodiesterase 10A (PDE10A) inhibitor,with anti-cancer activity.Fórmula:C8H9NOPureza:99.83%Forma y color:Physical Description Off-White Crystalline Solid (Ntp 1992)Peso molecular:135.16Anti-ALDH7A1 Antibody (5P692)
Anti-ALDH7A1 Antibody (5P692) is a Rabbit antibody targeting ALDH7A1. Anti-ALDH7A1 Antibody (5P692) can be used in FCM,ICC/IF.Forma y color:Odour LiquidBAY 73-6691
CAS:BAY 73-6691 is an inhibitor of brain penetrant PDE9A.Fórmula:C15H12ClF3N4OForma y color:SolidPeso molecular:356.73Dasantafil
CAS:Dasantafil (SCH446132) is a small molecule phosphodiesterase-5A (PDE5A) inhibitor used to treat genitourinary disorders and study erectile dysfunction.Fórmula:C22H28BrN5O5Pureza:98.64% - 99.16%Forma y color:SolidPeso molecular:522.39Amino Tadalafil
CAS:Amino tadalafil is a potent phosphodiesterase 5 (PDE5) inhibitor.Fórmula:C21H18N4O4Pureza:99.45%Forma y color:White PowderPeso molecular:390.39TyK2-IN-2
CAS:TyK2-IN-2 is a selective inhibitor of TYK2 (IC50s: 7 nM, 0.1 μM, and 0.05 μM for TYK2 JH2, IL-23, and IFNα).Fórmula:C16H18N6OPureza:98%Forma y color:SolidPeso molecular:310.35ATX inhibitor 1
CAS:ATX inhibitor 1 is a potent ATX inhibitor (IC50: 1.23 nM, FS-3 and 2.18 nM, bis-pNPP).Fórmula:C21H23Cl2N2O6PPureza:99.52%Forma y color:SolidPeso molecular:501.3PF-8380
CAS:PF-8380 is an effective and orally available autotaxin inhibitor (IC50: 2.8 nM, in isolated enzyme assay; 101 nM, in the human whole blood).Fórmula:C22H21Cl2N3O5Pureza:98.70% - 99.25%Forma y color:SolidPeso molecular:478.33Vardenafil
CAS:Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction.Fórmula:C23H32N6O4SPureza:99.88%Forma y color:SolidPeso molecular:488.6Nauclefine
CAS:Nauclefine, a plant alkaloid, triggers cancer cell death through PDE3A-SLFN12, binding but not inhibiting PDE3A.Fórmula:C18H13N3OPureza:99.92%Forma y color:SolidPeso molecular:287.32BAY 73-6691 racemate
CAS:BAY 73-6691 racemate (Rac-BAY 73-6691) is a phosphodiesterase 9A (PDE9A) inhibitor, useful for studying Parkinson’s disease.Fórmula:C15H12ClF3N4OForma y color:SolidPeso molecular:356.73
