FAAH
La hidrolasa de amidas de ácidos grasos (FAAH) es una enzima que descompone las amidas de ácidos grasos, incluidos los endocannabinoides como la anandamida. Estos compuestos están involucrados en la regulación del dolor, el estado de ánimo, el apetito y la memoria. La inhibición de la FAAH puede aumentar los niveles de estas moléculas de señalización, ofreciendo beneficios terapéuticos potenciales para el dolor, la ansiedad y las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos una selección de inhibidores de FAAH para apoyar su investigación en neurociencia, manejo del dolor y señalización endocannabinoide.
Productos de "FAAH"
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PDP-EA
CAS:PDP-EA is an activator of fatty acid amide hydrolase(FAAH) and enhances the amidohydrolase activity of FAAH.Fórmula:C25H43NO3Pureza:98.06%Forma y color:SolidPeso molecular:405.61OMDM-5
CAS:OMDM-5 is a potent vanilloid receptor type 1 (TRPV1, EC50 = 75 nM) agonist, showing weak ligand activity at cannabinoid type 1 receptor (CB1, Ki=4.9 μM).Fórmula:C26H44N2O3Pureza:99.72%Forma y color:SolidPeso molecular:432.64Ref: TM-T12306
1mg87,00€5mg187,00€10mg284,00€25mg452,00€50mg645,00€100mg867,00€200mg1.130,00€1mL*10mM (DMSO)221,00€FAAH inhibitor 1
CAS:FAAH inhibitor 1 (Benzothiazole analog 3) is an effective FAAH inhibitor with an IC50 of 18 nM.Fórmula:C24H23N3O3S3Pureza:98.05%Forma y color:SolidPeso molecular:497.65Ref: TM-T11256
1mg52,00€5mg116,00€10mg182,00€25mg306,00€50mg442,00€100mg620,00€200mg835,00€1mL*10mM (DMSO)128,00€ARN272
CAS:ARN272 is a FAAH-like anandamide transporter (FLAT) inhibitor (IC50: 1.8 μM).Fórmula:C27H20N4O2Pureza:98.23%Forma y color:SolidPeso molecular:432.47MAGL-IN-4
CAS:MAGL-IN-4 (His121 ARG57) is one of the monoacylglycerol lipase (MAGL) inhibitors in central nervous system-related diseases.Fórmula:C18H21ClN2O4Pureza:≥98%Forma y color:SolidPeso molecular:364.82Ref: TM-T9687
1mg140,00€5mg344,00€10mg512,00€25mg848,00€50mg1.121,00€100mg1.510,00€1mL*10mM (DMSO)373,00€VU534
CAS:VU534 is a NAPE-PLD agonist with an EC50 of 0.30 μM.VU534 is a dual inhibitor of FAAH and sEH, with an IC50 of 1.2 μM for sEH.VU534 is used in diseases relatedFórmula:C21H22FN3O3S2Pureza:99.22%Forma y color:SolidPeso molecular:447.55Sob-AM2
CAS:Sob-AM2 is an effective substrate targeting the fatty acid amide hydrolase (FAAH) expressed in the brain, with a Km of 1.3 μM. It delivers higher concentrations of Sobetirome to the central nervous system at minimal peripheral systemic doses, thereby activating the central thyroid hormone receptor β (TRβ).Fórmula:C21H27NO3Forma y color:SolidPeso molecular:341.44JNJ-1661010
CAS:JNJ-1661010 (Takeda-25) is an effective and specific FAAH inhibitor (IC50: 10/ 12 nM for rat/human), shows >100-fold selectivity for FAAH-1 than FAAH-2.Fórmula:C19H19N5OSPureza:99.79% - 99.97%Forma y color:SolidPeso molecular:365.454-Nonylphenylboronic acid
CAS:4-Nonylphenylboronic acid is a inhibitor of FAAH.Fórmula:C15H25BO2Pureza:97.63%Forma y color:SolidPeso molecular:248.17Biochanin A
CAS:Biochanin A: an isoflavone from red clover with anticancer properties and inhibits FAAH.Fórmula:C16H12O5Pureza:97.1% - 98.97%Forma y color:SolidPeso molecular:284.26N-Benzyllinolenamide
CAS:N-Benzyllinolenamide is a natural product. It is an inhibitor of fatty acid amide hydrolase (FAAH, IC50 of 41.8 μM).Fórmula:C25H37NOPureza:98.00% - 99.92%Forma y color:SolidPeso molecular:367.57Ref: TM-TN1965
1mg88,00€5mg187,00€10mg281,00€25mg475,00€50mg692,00€100mg935,00€200mg1.264,00€1mL*10mM (DMSO)188,00€JNJ-40355003
CAS:JNJ-40355003 is a FAAH inhibitor that increases plasma levels of fatty acid amides in rats, dogs, and crabs.Fórmula:C23H23ClN4O2Pureza:99.32%Forma y color:SolidPeso molecular:422.91MK-3168 (12C)
CAS:MK-3168 (12C) functions as a FAAH inhibitor, exhibiting IC50 values of 1.0 nM, 5.5 nM, and 1.7 nM for human, rhesus, and rat respectively. It demonstrates effective brain uptake and FAAH-specific signaling. Additionally, 11 C MK-3168 is applicable as a FAAH PET tracer.Fórmula:C21H21ClN4OSForma y color:SolidPeso molecular:412.94Palmitoylisopropylamide
CAS:Palmitoylisopropylamide is a selective FAAH inhibitor that inhibits [H]-AEA uptake and cell proliferation at low concentrations.Fórmula:C19H39NOPureza:100%Forma y color:SolidPeso molecular:297.52WWL 154
CAS:WWL 154 is an serine hydrolase (SH) and fatty acid amide hydrolase FAAH-4 inhibitor.Fórmula:C18H19N3O5Pureza:99.22%Forma y color:SolidPeso molecular:357.36Ref: TM-T8927
1mg46,00€5mg84,00€10mg106,00€25mg150,00€50mg207,00€100mg311,00€200mg444,00€1mL*10mM (DMSO)85,00€BuChE-IN-15
BuChE-IN-15, a chemical compound, exhibits potent inhibitory activity with IC50 values of 81 nM and 400 nM, respectively. It also demonstrates good blood-brain barrier permeability and neuroprotective properties, making it suitable for research in Alzheimer's disease.Fórmula:C18H18FNO4Forma y color:SolidPeso molecular:331.34PF-3845
CAS:PF-3845 is a potent, selective and irreversible FAAH inhibitor with Ki of 230 nM, showing negligible activity against FAAH2.Fórmula:C24H23F3N4O2Pureza:99.54% - 99.58%Forma y color:SolidPeso molecular:456.46Ref: TM-T6043
2mg42,00€5mg59,00€10mg97,00€25mg205,00€50mg354,00€100mg560,00€200mg800,00€1mL*10mM (DMSO)59,00€SA 47
CAS:SA 47 is a selective and effective inhibitor of fatty acid amide hydrolase and carbamate.Fórmula:C17H26N4O3Pureza:98%Forma y color:SolidPeso molecular:334.41Carprofen
CAS:Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.Fórmula:C15H12ClNO2Pureza:98.99% - 99.65%Forma y color:SolidPeso molecular:273.71JNJ-42165279
CAS:JNJ-42165279 selectively inactivates FAAH without notably affecting other enzymes, ion channels, receptors, or CYPs/hERG at 10 μM.Fórmula:C18H17ClF2N4O3Pureza:99.88% - 99.89%Forma y color:SolidPeso molecular:410.8Ref: TM-T3215
2mg46,00€5mg65,00€10mg96,00€25mg170,00€50mg246,00€100mg363,00€200mg512,00€1mL*10mM (DMSO)75,00€
