NAMPT
La nicotinamida fosforribosiltransferasa (NAMPT) es una enzima involucrada en la biosíntesis de nicotinamida adenina dinucleótido (NAD+), un coenzima crítico en el metabolismo celular y la producción de energía. Los inhibidores de NAMPT son de interés en la investigación del cáncer debido a su capacidad para interrumpir el metabolismo de NAD+ e inducir la muerte celular en células cancerosas. Estos inhibidores también se exploran en el contexto de trastornos metabólicos y envejecimiento. En CymitQuimica, ofrecemos inhibidores de NAMPT para apoyar su investigación en biología del cáncer, metabolismo y envejecimiento.
Productos de "NAMPT"
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Hay 20 productos en esta categoría.
GNE-617
CAS:GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer.Fórmula:C21H15F2N3O3SPureza:99.28% - 99.97%Forma y color:SolidPeso molecular:427.42Ref: TM-T4335
1mg40,00€2mg52,00€5mg85,00€10mg124,00€25mg219,00€50mg350,00€100mg522,00€500mg1.130,00€1mL*10mM (DMSO)86,00€Nampt-IN-14
CAS:Nampt-IN-14 (example 3) is an effective NAMPT inhibitor with an IC50 of 0.2 nM, suited for use in the synthesis of antibody-drug conjugates (ADCs).Fórmula:C33H35N7O2Forma y color:SolidPeso molecular:561.68CHS-828
CAS:CHS-828 (GMX1778), a pyridyl cyanoguanidine, is an effective inhibitor of NAD+ biosynthesis enzyme NAMPT (IC50 <25 nM).Fórmula:C19H22ClN5OPureza:100% - 99.76%Forma y color:SolidPeso molecular:371.86(E)-Daporinad
CAS:(E)-Daporinad (FK866) is a highly specific, non-competitive inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .Cost-effective and quality-assured.Fórmula:C24H29N3O2Pureza:100% - 99.96%Forma y color:SolidPeso molecular:391.51Ref: TM-T2644
2mg43,00€5mg65,00€10mg96,00€25mg188,00€50mg368,00€100mg557,00€500mg1.169,00€1mL*10mM (DMSO)70,00€STF-118804
CAS:STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL cell lines with IC50 <10 nM.Fórmula:C25H23N3O4SPureza:98.66%Forma y color:SolidPeso molecular:461.53Nampt-IN-5
CAS:Nampt-IN-5 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (NAMPT) .Fórmula:C25H25N5O2Pureza:99.3%Forma y color:SolidPeso molecular:427.5Ref: TM-T12171
1mg81,00€5mg156,00€10mg264,00€25mg419,00€50mg562,00€100mg775,00€200mg1.026,00€1mL*10mM (DMSO)170,00€Nampt activator-1
CAS:NAMPT Activator-1, EC50: 3.3-3.7 µM, specific niacinamide phosphotransferase stimulant, shields cells, potential neuroprotectant.Fórmula:C16H17N3O3Pureza:99.98% - 99.98%Forma y color:SoildPeso molecular:299.32LB-60-OF61
CAS:LB-60-OF61 is a NAMPT inhibitor, a NAMPT inhibitor that displays antiproliferative activity against MYC oncogene-dependent cancer cell lines.Fórmula:C29H30N6O2Pureza:100%Forma y color:SolidPeso molecular:494.59Ref: TM-T11823
1mg162,00€5mg393,00€10mg645,00€25mg1.254,00€50mg2.118,00€100mg3.307,00€1mL*10mM (DMSO)425,00€Nampt-IN-15
CAS:Nampt-IN-15 (Example 3) is a Nampt inhibitor that exhibits cytotoxic effects on various cell lines, including BxPC-3, HepG2, L540cy, and MOLM-13. The respective IC50 values for these cell lines are 38.5 nM, 8 nM, 8.5 nM, and 7 nM.Fórmula:C24H30N4O2Forma y color:SolidPeso molecular:406.52Nampt-IN-13
CAS:Nampt-IN-13 (example 58m) is an NAMPT inhibitor used in the synthesis of antibody-drug conjugates (ADCs).Fórmula:C24H30N6O2Forma y color:SolidPeso molecular:434.53CB30865
CAS:CB30865 (ZM 242421) is a selective and highly effective nicotinamide phosphoribosyltransferase (Nampt) inhibitor with potential antitumor activity.Fórmula:C26H22BrN5O2Pureza:99.04%Forma y color:SolidPeso molecular:516.39NAMPT Protein, Human, Recombinant (His)
Pre-B cell colony enhancing factor (PBEF) was originally identified as a cytokine that potentiated the clonal expansion and differentiation of pre-B cells, butPureza:94% - 94%Forma y color:Lyophilized PowderPeso molecular:55 KDa (reducing condition)Nampt-IN-1
CAS:Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.Fórmula:C20H25N3O5SPureza:96.82% - 99.4%Forma y color:SolidPeso molecular:419.49Ref: TM-T4376
1mg39,00€2mg52,00€5mg84,00€10mg137,00€25mg259,00€50mg432,00€100mg638,00€1mL*10mM (DMSO)92,00€NAMPT degrader-3
NAMPT Degrader-3 (compound C5) is a NAMPT degrader that functions through a VHL- and proteasome-dependent mechanism.Fórmula:C56H74N8O7SPureza:98%Forma y color:SolidPeso molecular:1003.3SBI-797812
CAS:SBI-797812 is structurally similar to active-site directed inhibitor of NAMPT(NAMPT with EC50 of 0.37 μM).Fórmula:C19H22N4O4SPureza:99.31%Forma y color:SolidPeso molecular:402.47Ref: TM-T12854
1mg59,00€5mg120,00€10mg212,00€25mg369,00€50mg593,00€100mg932,00€200mg1.264,00€1mL*10mM (DMSO)105,00€Teglarinad chloride
CAS:Teglarinad chloride (GMX-1777 chloride) is an inhibitor of NAMPT with antitumor activity that acts by interfering with DNA repair and inhibiting angiogenesis.Fórmula:C30H43Cl2N5O8Pureza:98.09%Forma y color:SolidPeso molecular:672.6OT-82
CAS:OT-82 is a NAMPT inhibitor with anticancer activity and cytotoxicity and is used in the study of leukemias.Fórmula:C26H21FN4OPureza:98.91% - 98.91%Forma y color:SolidPeso molecular:424.47KPT9274
CAS:KPT9274 (PAK4-IN-1) is a non-competitive dual inhibitor of PAK4 and NAMPT(IC50= ~120 nM). It is an orally bioavailable small molecule.Fórmula:C35H29F3N4O3Pureza:99.75% - 99.93%Forma y color:SolidPeso molecular:610.62GNE-618
CAS:GNE-618 is a potent and orally active inhibitor of nicotinamide phosphoribosyltransferase (IC50: 6 nM).Fórmula:C21H15F3N4O3SForma y color:SolidPeso molecular:460.43ALT-100 (Human IgG1)
ALT-100 (HumanIgG1) is a human-derived IgG1 monoclonal antibody that targets NAMPT. For its isotype control, please refer to HumanIgG1kappa, Isotype Control.Forma y color:Odour Liquid
