PKM
La Piruvato Quinasa M2 (PKM2) es una isoforma de la piruvato quinasa que desempeña un papel crucial en la glucólisis, convirtiendo fosfoenolpiruvato en piruvato. PKM2 está involucrada en la regulación de la reprogramación metabólica en células cancerosas, lo que la convierte en un objetivo potencial para la terapia contra el cáncer. Los inhibidores de PKM2 pueden alterar las vías metabólicas, reducir el crecimiento tumoral e inducir la muerte celular en las células cancerosas. En CymitQuimica, ofrecemos inhibidores de PKM2 para apoyar su investigación en metabolismo del cáncer, oncología y desarrollo terapéutico.
Productos de "PKM"
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Hay 10 productos en esta categoría.
DASA-58
CAS:DASA-58 is a specific and potent Pyruvate kinase M2 (PKM2) activator.Fórmula:C19H23N3O6S2Pureza:96.96% - 99.28%Forma y color:SolidPeso molecular:453.53PKM2-IN-1
CAS:PKM2-IN-1 (compound 3k) displays PKM2 inhibitory activity with the IC50 value of 2.95 μM. The IC50 value for PKM1 is 4-5-fold higher than that for PKM2.Fórmula:C18H19NO2S2Pureza:99.49% - 99.68%Forma y color:SolidPeso molecular:345.48Ref: TM-T4170
1mg40,00€2mg51,00€5mg85,00€10mg115,00€25mg205,00€50mg354,00€100mg567,00€200mg810,00€500mg1.216,00€PKM2 activator 2
CAS:PKM2 activator 2 is a pyruvate kinase M2 (PKM2) activator with an AC 50 value of 66 nM.PKM2 activator 2 has anti-tumor proliferative properties and attenuatesFórmula:C20H18F2N2O4S2Pureza:100%Forma y color:SolidPeso molecular:452.49Mitapivat sulfate hydrate
CAS:Mitapivat sulfate hydrate (AG 348 sulfate hydrate) is a pyruvate kinase (PK) allosteric activator, used to study pyruvate kinase deficiency.Fórmula:C24H26N4O3S1H2SO43H2OPureza:99.40%Forma y color:SolidPeso molecular:526.6Mitapivat
CAS:Mitapivat (PKR-IN-1), also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.Fórmula:C24H26N4O3SPureza:99.47% - 99.83%Forma y color:SolidPeso molecular:450.55TEPP-46
CAS:TEPP-46 (ML265) is an activator of pyruvate kinase M2 (PKM2), selective for PKM1, PKL and PKR. TEPP-46 has antitumor activity. Cost-effective and quality-assured.Fórmula:C17H16N4O2S2Pureza:98.21% - 98.77%Forma y color:SolidPeso molecular:372.46Ref: TM-T7214
1mg48,00€5mg96,00€10mg144,00€25mg235,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)96,00€PKM2 activator 5
CAS:PKM2 activator 5 is a novel and potent PKM2 activator (AC50: 0.316 µM) with potential anticancer activity for the study of cancer metabolism-related diseases.Fórmula:C18H19FN2O6S2Pureza:98%Forma y color:SolidPeso molecular:442.48Dimethylaminomicheliolide HCl
CAS:Dimethylaminomicheliolide HCl has potential anti-inflammatory and anti-tumor activity and inhibits the proliferation of glioblastoma cells by targeting pyruvateFórmula:C17H28ClNO3Pureza:99.55%Forma y color:SoildPeso molecular:329.86PKR-IN-2
CAS:PKR-IN-2 is a activator of pyruvate kinase (PKR).Fórmula:C24H28N4O4SPureza:99.14%Forma y color:SolidPeso molecular:468.57Ref: TM-T12499
1mg81,00€5mg145,00€10mg207,00€25mg334,00€50mg467,00€100mg655,00€200mg883,00€1mL*10mM (DMSO)149,00€PKM2 inhibitor G
CAS:PKM2 inhibitor G is a inhibitor of pyruvate kinase.Fórmula:C16H15NO3SPureza:99.54%Forma y color:SoildPeso molecular:301.36Ref: TM-T67900
1mg185,00€5mg425,00€10mg625,00€25mg938,00€50mg1.311,00€100mg1.795,00€1mL*10mM (DMSO)404,00€
