Beta amiloide
Beta amyloid inhibitors are compounds that specifically target and inhibit the formation or aggregation of beta-amyloid peptides, which are critically involved in the pathogenesis of Alzheimer's disease. The accumulation of beta-amyloid plaques in the brain is one of the key pathological features of Alzheimer's, contributing to neuronal dysfunction, synaptic loss, and cognitive decline. By preventing the aggregation of beta-amyloid, these inhibitors are being actively researched as potential therapeutic agents aimed at slowing down or even halting the progression of Alzheimer's disease. At CymitQuimica, we offer a variety of high-quality beta-amyloid inhibitors to support your research in neurodegenerative disorders, protein aggregation, and the development of Alzheimer's therapies.
Productos de "Beta amiloide"
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Cedrin
CAS:Cedrin has protective effects on PC12 cells against the neurotoxicity induced by amyloid β1-42, the protective effect is related to the inhibition of oxidativeFórmula:C16H14O8Pureza:98%Forma y color:SolidPeso molecular:334.28LX2343
CAS:LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Fórmula:C22H19ClN2O6SPureza:99.45%Forma y color:SolidPeso molecular:474.91Ref: TM-T4398
2mg37,00€5mg52,00€10mg84,00€25mg137,00€50mg229,00€100mg340,00€200mg472,00€1mL*10mM (DMSO)58,00€β-Amyrin
CAS:β-Amyrin (beta-Amyrin) has antiviral, hepatoprotective, antinociceptive, anti-inflammatoryFórmula:C30H50OPureza:96.49%Forma y color:White Crystalline PowderPeso molecular:426.72BMS 433796
CAS:BMS 433796 is a γ-secretase inhibitor that demonstrates Aβ-lowering activity within a transgenic mouse model of Alzheimer's disease.Fórmula:C21H20F2N4O4Pureza:99.17%Forma y color:SolidPeso molecular:430.4LY 2389575 hydrochloride
CAS:LY2389575 hydrochloride is a selective mGlu3 NAM with 190 nM IC50, increases Mrc1, and aids Alzheimer's research.Fórmula:C15H16BrCl3N4Pureza:100%Forma y color:SolidPeso molecular:438.58Saikosaponin C
CAS:Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.Fórmula:C48H78O17Pureza:98% - 99.94%Forma y color:SolidPeso molecular:927.12Ginsenoside Rg2
CAS:Ginsenoside Rg2 (Chikusetsusaponin I) is one of the major active components of ginseng, act as an NF-κB inhibitor.Fórmula:C42H72O13Pureza:99.5% - 99.77%Forma y color:SolidPeso molecular:785.01Ref: TM-T2873
2mg37,00€5mg52,00€10mg88,00€25mg131,00€50mg188,00€100mg279,00€500mg658,00€1mL*10mM (DMSO)87,00€Azeliragon
CAS:Azeliragon (TTP488) is an antagonist at the Receptor for Advanced Glycation End products; is evaluated as a potential treatment for patients with mild-to-Fórmula:C32H38ClN3O2Pureza:96.7% - 98.32%Forma y color:SolidPeso molecular:532.12FPS-ZM1
CAS:FPS-ZM1 is a high-affinity RAGE specific inhibitor that blocks Aβ binding to the V domain of RAGE.Fórmula:C20H22ClNOPureza:98.39% - 99.3%Forma y color:SolidPeso molecular:327.85Ref: TM-T3259
5mg50,00€10mg57,00€25mg92,00€50mg147,00€100mg220,00€200mg350,00€500mg590,00€1mL*10mM (DMSO)52,00€MDR-1339
CAS:MDR-1339 is a blood-brain-barrier-permeable inhibitor of amyloid-β (Aβ) aggregation.Fórmula:C20H22O4Pureza:98.57%Forma y color:SolidPeso molecular:326.39Hederacolchiside E
CAS:Hederacolchiside E: antioxidant, neuroprotective in AD, reduces oxidative stress, inhibits lipid peroxidation.Fórmula:C65H106O30Pureza:99.78%Forma y color:SolidPeso molecular:1367.52Scyllo-Inositol
CAS:Scyllo-Inositol (Scyllitol) is one of the inositol stereoisomers, rare in the nature, and expected as a promising disease-modifying therapeutic agent forFórmula:C6H12O6Pureza:99.87% - ≥95%Forma y color:SolidPeso molecular:180.16Aftin-4
CAS:Aftin-4, an amyloid forty-two inducer, activates γ-secretase, promoting the generation of amyloid-β-1-42 (Aβ1-42) from amyloid-β protein precursor.Fórmula:C20H28N6OPureza:98.51%Forma y color:SolidPeso molecular:368.48Ref: TM-T4364
2mg42,00€5mg80,00€10mg116,00€25mg226,00€50mg335,00€100mg480,00€200mg652,00€1mL*10mM (DMSO)64,00€Tramiprosate
CAS:Tramiprosate (Alzhemed) is an orally active, BBB-crossing, naturally occurring amino acid that binds soluble Aβ and maintains it in a non-protofibrillar form.Fórmula:C3H9NO3SPureza:99%Forma y color:White Crystals Or Crystalline PowerPeso molecular:139.17Mirabijalone D
CAS:Mirabijalone D is a non-competitive inhibitor based on the Dixon plot.It inhibits Aβ1-42 production by 43.7% in APPSW-N2a cells.Fórmula:C18H14O7Pureza:98%Forma y color:SolidPeso molecular:342.3EUK-134
CAS:EUK-134, a synthetic SOD/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.Fórmula:C18H18ClMnN2O4Pureza:98.39%Forma y color:SolidPeso molecular:416.74Ref: TM-T6495
10mg35,00€25mg66,00€50mg104,00€100mg160,00€200mg230,00€500mg378,00€1mL*10mM (DMSO)47,00€1H-Indole-3-carboxylic acid, 5-[2-hydroxy-3-[[2-hydroxy-1,1-bis(hydroxymethyl)ethyl]amino]propoxy]-2-methyl-1-(4-methylphenyl)-, ethyl ester
CAS:Compound 5936-0108对β-淀粉样蛋白可能具有调节作用。Fórmula:C26H34N2O7Pureza:99.44%Forma y color:SoildPeso molecular:486.56Ref: TM-T67751
1mg313,00€5mg758,00€10mg1.035,00€25mg1.568,00€50mg2.118,00€100mg2.783,00€1mL*10mM (DMSO)945,00€C18 L-erythro Ceramide (d18:1/18:0)
CAS:C18 L-erythro Ceramide, a natural stereoisomer, inhibits rat brain mt-CDase with IC50 of 8.8 μM.Fórmula:C36H71NO3Forma y color:SolidPeso molecular:565.95TAE-1
CAS:TAE-1 is an inhibitor of amyloid-β fibril formation and aggregation. It inhibits cholinesterases AChE and BuChE with IC50 of 0.3 μM and 3.9 μM, respectively.Fórmula:C39H51I3N6O9Pureza:≥95%Forma y color:SolidPeso molecular:1128.57Cu(II)GTSM
CAS:Cu(II)GTSM is a cell permeable copper complex inhibits GSK3β activity and suppresses levels of neurotoxic amyloid β-trimers and phosphorylated tau.Fórmula:C6H10CuN6S2Pureza:99.21%Forma y color:SolidPeso molecular:293.86Ref: TM-T40792
1mg38,00€5mg80,00€10mg126,00€25mg277,00€50mg472,00€100mg790,00€200mg1.074,00€1mL*10mM (DMSO)87,00€
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