BACE
Los inhibidores de BACE son compuestos que tienen como objetivo la enzima Beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE), que es crucial para la producción de beta-amiloide, una proteína asociada con la formación de placas amiloides en la enfermedad de Alzheimer. Al inhibir BACE, estos compuestos buscan reducir la producción de beta-amiloide y su acumulación en el cerebro, lo que podría ralentizar la progresión de la enfermedad de Alzheimer. Los inhibidores de BACE son un enfoque principal en el desarrollo de estrategias terapéuticas para las enfermedades neurodegenerativas. En CymitQuimica, ofrecemos inhibidores de BACE para apoyar su investigación en la enfermedad de Alzheimer, la biología amiloide y la neurodegeneración.
Productos de "BACE"
Ordenar por
Anti-BACE1 Antibody (8D358)
Anti-BACE1 Antibody (8D358) is a Rabbit antibody targeting BACE1. Anti-BACE1 Antibody (8D358) can be used in FCM,ICC/IF.Forma y color:Odour LiquidAtabecestat
CAS:Atabecestat (JNJ-54861911) is an oral BACE1 inhibitor for Alzheimer's treatment with strong brain uptake and lasting PK/PD effects.Fórmula:C18H14FN5OSPureza:98.49% - 99.77%Forma y color:SolidPeso molecular:367.4Ref: TM-T14338
1mg130,00€5mg311,00€10mg502,00€25mg1.008,00€50mg1.349,00€100mg1.825,00€1mL*10mM (DMSO)344,00€Umibecestat
CAS:Umibecestat inhibits human and mouse BACE-1 (IC50: 11 nM & 10 nM), potentially for Alzheimer's research.Fórmula:C19H15ClF7N5O2Pureza:100%Forma y color:SolidPeso molecular:513.8Ref: TM-T13253
1mg172,00€5mg354,00€10mg512,00€25mg852,00€50mg1.159,00€100mg1.568,00€1mL*10mM (DMSO)418,00€Anti-BACE1 Antibody (3R945)
Anti-BACE1 Antibody (3R945) is a Mouse antibody targeting BACE1. Anti-BACE1 Antibody (3R945) can be used in ELISA.Forma y color:Odour LiquidLY2811376
CAS:LY2811376, an orally available non-peptidic β-secretase(BACE1) inhibitor (IC50: 239-249 nM), can decrease Aβ secretion (EC50: 300 nM).Fórmula:C15H14F2N4SPureza:99% - 99.01%Forma y color:SolidPeso molecular:320.36Ref: TM-T2639
1mg52,00€2mg73,00€5mg123,00€10mg205,00€25mg374,00€50mg560,00€100mg800,00€1mL*10mM (DMSO)123,00€LX2343
CAS:LX2343 inhibits BACE1 (IC50: 11.43 μM) and PI3K non-competitively (IC50: 15.99 μM), and enhances autophagy for Aβ removal.Fórmula:C22H19ClN2O6SPureza:99.45%Forma y color:SolidPeso molecular:474.91Ref: TM-T4398
2mg37,00€5mg52,00€10mg84,00€25mg137,00€50mg229,00€100mg340,00€200mg472,00€1mL*10mM (DMSO)58,00€Questin
CAS:Questin is an antimicrobial agent derived from Aspergillus florescens with an antimicrobial activity profile that inhibits V.Fórmula:C16H12O5Pureza:98%Forma y color:SolidPeso molecular:284.26Verubecestat
CAS:Verubecestat (MK-8931) (MK-8931) is an effective and specific β-secretase inhibitor and β-site APP-cleaving enzyme 1 inhibitor or BACE1 protein inhibitor.Fórmula:C17H17F2N5O3SPureza:99.49% - ≥98%Forma y color:SolidPeso molecular:409.41Ref: TM-T7011
2mg40,00€5mg60,00€10mg88,00€25mg153,00€50mg216,00€100mg354,00€500mg825,00€1mL*10mM (DMSO)66,00€AZD3839 free base
CAS:AZD3839 free base is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.Fórmula:C24H16F3N5Pureza:99.93% - 99.96%Forma y color:SolidPeso molecular:431.41Ref: TM-T6772
1mg52,00€2mg74,00€5mg114,00€10mg170,00€25mg344,00€50mgA consultar1mL*10mM (DMSO)120,00€Tenuifolin
CAS:Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.Fórmula:C36H56O12Pureza:97.37% - 99.9%Forma y color:SolidPeso molecular:680.82SEW06622
CAS:SEW06622 is a inhibitor of acetylcholinesterase (AChE) and beta-secretase-1 (BACE-1) and is a potential candidate for the treatment of Alzheimer's disease.Fórmula:C21H26N2O2Pureza:99.87%Forma y color:SoildPeso molecular:338.44Elenbecestat
CAS:Elenbecestat (E2609) is an effective oral bioutilization and CNS penetrating ACE-1 inhibitor for the treatment of Alzheimer's disease.Fórmula:C19H18F3N5O2SPureza:99.95%Forma y color:SolidPeso molecular:437.44Ref: TM-T11175
1mg70,00€5mg153,00€10mg250,00€25mg520,00€50mg750,00€100mg1.026,00€1mL*10mM (DMSO)166,00€Anti-BACE1 Antibody (2J206)
Anti-BACE1 Antibody (2J206) is an antibody targeting BACE1. Anti-BACE1 Antibody (2J206) can be used in ELISA, WB.Forma y color:Odour LiquidLY2886721
CAS:LY2886721, a BACE inhibitor, is used for the therapy of Alzheimer's Disease.Fórmula:C18H16F2N4O2SPureza:99% - 99.94%Forma y color:SolidPeso molecular:390.41BACE1 Protein, Human, Recombinant (hFc)
BACE1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag.Forma y color:Lyophilized PowderPeso molecular:75 kDa (predicted); 100-105 kDa (reducing condition, due to glycosylation)BACE1-IN-2
CAS:BACE1-IN-2 is a BACE1 inhibitor (IC50: 22 nM).Fórmula:C19H15F4N5O2Pureza:98%Forma y color:SolidPeso molecular:421.35Anti-BACE1 Antibody (2Z488)
Anti-BACE1 Antibody (2Z488) is a Mouse antibody targeting BACE1. Anti-BACE1 Antibody (2Z488) can be used in ELISA.Forma y color:Odour LiquidPF-06751979
CAS:PF-06751979 is an inhibitor of β-site amyloid precursor protein cleaving enzyme 1 (BACE1) (IC50 of 7.3 nM in BACE1 binding assay).Fórmula:C18H19F2N5O3S2Pureza:98%Forma y color:SolidPeso molecular:455.5Anti-BACE1 Antibody-FITC (8D358)
Anti-BACE1 Antibody-FITC (8D358) is a FITC-conjugated Rabbit antibody targeting BACE1. Anti-BACE1 Antibody-FITC (8D358) can be used in FCM.Forma y color:Odour LiquidUmibecestat HCl
CAS:Umibecestat HCl (CNP520 HCl) is an efficient β-secretase (BACE1/BACE2) inhibitor that reduces Aβ levels in mice and rats.Fórmula:C19H16Cl2F7N5O2Pureza:99.92%Forma y color:SolidPeso molecular:550.26
