Receptor activado por proteasa
Los inhibidores del Receptor Activado por Proteasas (PAR) son compuestos que se dirigen e inhiben la actividad de los PARs, una familia de receptores acoplados a proteínas G que se activan por escisión proteolítica. Estos receptores desempeñan un papel en diversos procesos fisiológicos, incluidos la coagulación, la inflamación y la reparación de tejidos. Los inhibidores de PAR son herramientas valiosas para estudiar los mecanismos de estos procesos y su implicación en enfermedades como el cáncer, trastornos cardiovasculares y la inflamación crónica. En CymitQuimica, ofrecemos inhibidores de PAR para apoyar su investigación en transducción de señales, respuesta inmunitaria y descubrimiento terapéutico.
Productos de "Receptor activado por proteasa"
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Hay 16 productos en esta categoría.
SCH79797
CAS:SCH79797 is a potent and specific protease-activated receptor 1 (PAR1) antagonistwith antimicrobial, anticancer, anti-inflammatory, and neuroprotective effects.Fórmula:C23H25N5Pureza:99.80%Forma y color:SolidPeso molecular:371.48Parmodulin 2
CAS:ML161 (Parmodulin 2) inhibits PAR1, blocking platelet activation and thrombin-induced activity (IC50: 0.26μM).Fórmula:C17H17BrN2O2Pureza:96.72% - 99.95%Forma y color:SolidPeso molecular:361.23BMS-986141
CAS:BMS-986141(UDM-003183) is a selective and potent protease-activated receptor-4 (PAR-4) antagonist with oral activity and an IC50 value of 0.4 nM.BMS-98614Fórmula:C27H23N5O5S2Pureza:98.36% - 99.11%Forma y color:SolidPeso molecular:561.63Thrombin Receptor Activator for Peptide
Thrombin Receptor Activator (TRAP) or Coagulation Factor II (1-5), used in CHD research.Fórmula:C32H51F3N8O9Pureza:99.88%Forma y color:SolidPeso molecular:748.79ML-354
CAS:ML354 is a selective antagonist of PAR4 with an IC 50 of 140 nM [1].Fórmula:C16H14N2O3Pureza:99.44%Forma y color:SolidPeso molecular:282.29Vorapaxar sulfate
CAS:Vorapaxar sulfate (Zontivity) is a potent and orally active thrombin receptor (PAR-1) antagonist.Fórmula:C29H35FN2O8SPureza:99.46% - 99.91%Forma y color:SolidPeso molecular:590.66Ref: TM-T3098
1mg38,00€2mg49,00€5mg79,00€10mg119,00€25mg210,00€50mg354,00€100mg528,00€500mg1.159,00€1mL*10mM (DMSO)99,00€I-191
CAS:I-191 is a potent antagonist of protease-activated receptor 2 (PAR2), inhibits multiple signaling functions in human cancer cells.Fórmula:C23H26FN5O2Pureza:99.80%Forma y color:SolidPeso molecular:423.48Ref: TM-T7137
1mg89,00€2mg116,00€5mg188,00€10mg284,00€25mg474,00€50mg688,00€100mg938,00€1mL*10mM (DMSO)210,00€AC-264613
CAS:AC-264613 is an agonist of the GPCR protease-activated receptor 2 (PAR2). AC-264613 suppresses interferon regulatory factor 5.Fórmula:C19H18BrN3O2Pureza:98%Forma y color:SolidPeso molecular:400.28Atopaxar
CAS:Atopaxar (E5555), a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Fórmula:C29H38FN3O5Pureza:98.25% - 98.5%Forma y color:SolidPeso molecular:527.63PAR-2-IN-1
CAS:PAR-2-IN-1 (IUN76750) is a PAR- 2 signaling pathway inhibitor with anti-inflammatory and anticancer effects.Fórmula:C12H14ClN3O2Pureza:99.75%Forma y color:SolidPeso molecular:267.71Ref: TM-T8917
2mg35,00€5mg52,00€10mg90,00€25mg170,00€50mg255,00€100mg375,00€200mg530,00€1mL*10mM (DMSO)56,00€PAR650097
PAR650097 is a humanized monoclonal antibody targeting PAR2, used in migraine research.Peso molecular:145.5Protease-Activated Receptor-4 diTFA
Protease-Activated Receptor-4 diTFA,2454 is the proteinase-activated receptor-4 (PAR4)agonistFórmula:C37H48F6N8O11Pureza:98.54%Forma y color:SolidPeso molecular:894.81Ref: TM-T7740
1mg48,00€2mg60,00€5mg86,00€10mg138,00€25mg274,00€50mg411,00€100mg607,00€1mL*10mM (DMSO)170,00€Atopaxar Hydrobromide
CAS:Atopaxar, a reversible PAR-1 thrombin receptor antagonist, interferes with platelet signaling.Fórmula:C29H39BrFN3O5Pureza:98%Forma y color:SolidPeso molecular:608.54ENMD-1068 HCl
CAS:ENMD-1068 HCl (ENMD 1068) is a PAR-2 antagonist. ENMD-1068 HCl inhibits the development of endometriosis in a mouse model.Fórmula:C15H29N3O2Pureza:95.79%Forma y color:SolidPeso molecular:283.41AZ3451
CAS:AZ3451 is an allosteric antagonist of protease-activated receptor-2 (PAR2, IC50: 23 nM).Fórmula:C30H27BrN4O3Pureza:98.12%Forma y color:SolidPeso molecular:571.46Vorapaxar
CAS:Vorapaxar (MK-5348) (SCH 530348) is an effective and orally active thrombin receptor (PAR-1) antagonist (Ki: 8.1 nM).Fórmula:C29H33FN2O4Pureza:98.77% - 99.93%Forma y color:SolidPeso molecular:492.58Ref: TM-T7013
1mg74,00€5mg145,00€10mg216,00€25mg393,00€50mg587,00€100mg835,00€500mg1.663,00€1mL*10mM (DMSO)160,00€
