Células madre y Derivados
Los inhibidores de células madre son compuestos que se dirigen específicamente a las vías de señalización y proteínas involucradas en el mantenimiento, diferenciación y proliferación de células madre. Estos inhibidores son cruciales para comprender la biología de las células madre y para desarrollar estrategias que permitan manipularlas con fines terapéuticos, como en la medicina regenerativa y el tratamiento del cáncer. Al controlar el destino de las células madre, estos inhibidores pueden ayudar a guiar la diferenciación de células madre en tipos celulares específicos o prevenir el crecimiento celular no deseado. En CymitQuimica, ofrecemos una selección de inhibidores de células madre de alta calidad para apoyar su investigación en biología de células madre, biología del desarrollo y medicina regenerativa.
Subcategorías de "Células madre y Derivados"
- Gamma-secretasa
- Hedgehog / Smoothened
- Hippo pathway
- JAK
- Porcupine (Puerco espín)
- ROCK
- STAT
- Células madre
- TGF-beta / Smad
- Wnt / beta-catenina
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Productos de "Células madre y Derivados"
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VT107
CAS:VT107 is a potent pan-TEAD autopalmitoylation inhibitor. VT-107 can be used in cancer therapy research.Cost-effective and quality-assured.Fórmula:C25H20F3N3OPureza:98.43% - 99.73%Forma y color:SolidPeso molecular:435.44Ref: TM-T35545
1mg137,00€5mg329,00€10mg502,00€25mg810,00€50mg1.103,00€100mg1.483,00€200mg1.985,00€1mL*10mM (DMSO)360,00€Pentabromophenol
CAS:Pentabromophenol (NSC-5717) suppressed TGF-β response by accelerating the turnover rate of TGF-β receptors.Fórmula:C6HBr5OPureza:98.89%Forma y color:Monoclinic Prisms From Acetic Acid; Needles From Alcohol Physical Description Light Brown Powder Insoluble In Water (Ntp 1992)Peso molecular:488.59HODHBt
CAS:HODHBt is a STAT5-SUMO protein-protein interaction inhibitor.Fórmula:C7H5N3O2Pureza:99.45% - 99.95%Forma y color:Off-White To Yellow SolidPeso molecular:163.13dCK1α-2
dCK1α-2 is an orally effective CK1α molecular glue (Molecular Glue) degrader that targets p53 pathway-related targets. It demonstrates antitumor efficacy in mouse models by enhancing the expression of p53-related genes.Fórmula:C24H24ClN5O4Forma y color:SolidPeso molecular:481.93GSK-3β inhibitor 11
CAS:GSK-3β inhibitor 11 (compound 21) is a potent inhibitor of glycogen synthase kinase-3β (GSK-3β) with an inhibitory concentration (IC50) of 10.02 μM.Fórmula:C20H15N3O4SPureza:97.33%Forma y color:SolidPeso molecular:393.42BRD5648
CAS:BRD5648 ((R)-BRD0705) is an inactive (R)-enantiomer of BRD0705.Fórmula:C20H23N3OPureza:99.37%Forma y color:SolidPeso molecular:321.42Linavonkibart
CAS:Linavonkibart (SRK181) is a humanized antibody targeting TGFβ1 that blocks the release of TGF-β1 protein by specifically binding latent TGF-β1.Pureza:95% - 95%Forma y color:LiquidXMU-MP-1
CAS:XMU-MP-1 is an inhibitor of the pro-apoptotic, sterile 20-like kinases MST1 and 2.Fórmula:C17H16N6O3S2Pureza:99.68% - 99.68%Forma y color:SolidPeso molecular:416.48Ref: TM-T4212
1mg52,00€2mg79,00€5mg97,00€10mg153,00€25mg305,00€50mg512,00€100mg740,00€1mL*10mM (DMSO)95,00€SSTC3
CAS:SSTC3 is a casein kinase 1α (CK1α) activator with potential antitumor activity that inhibits WNT signaling.Fórmula:C23H17F3N4O3S2Pureza:98.65%Forma y color:SolidPeso molecular:518.53GSK-3 inhibitor 4
CAS:Orally active GSK-3 inhibitor 4 targets GSK-3α/β, CDK2/5 (IC50: 0.45-0.68 μM) and may aid in Alzheimer's research by lowering Tau protein.Fórmula:C22H15F2N5OPureza:98.77%Forma y color:SoildPeso molecular:403.38Ref: TM-T77341
1mg333,00€5mg922,00€10mg1.140,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg3.734,00€GSK269962A
CAS:GSK269962A (GSK269962A HCl) is a selective ROCK(Rho-associated protein kinase) inhibitor with IC50 values of 1.6 and 4 nM for ROCK1 and ROCK2, respectively.Fórmula:C29H30N8O5Pureza:99.14% - 99.71%Forma y color:SolidPeso molecular:570.6Akt/ROCK-IN-1
Akt/ROCK-IN-1 (B12) is a dual inhibitor targeting Akt and ROCK, exhibiting IC50 values of 0.023 nM and 1.47 nM, respectively.Fórmula:C21H19BrF2N4O2SPureza:98%Forma y color:SolidPeso molecular:509.37SHR0302
CAS:SHR0302 (ARQ252) is a JAK inhibitor that binds JAK1 with stronger affinity than others (Selectivity for JAK1 is more than 10 times for JAK2, 77 times for JAK3,Fórmula:C18H22N8O2SPureza:99.11%Forma y color:SolidPeso molecular:414.48Ref: TM-T9195
1mg160,00€5mg393,00€10mg620,00€25mg1.035,00€50mg1.483,00€100mg1.882,00€1mL*10mM (DMSO)455,00€lirucitinib
CAS:Lirucitinib is a JAK inhibitor known for its anti-inflammatory properties.Fórmula:C16H25N5OSForma y color:SolidPeso molecular:335.468STX-0119
CAS:STX-0119 is a selective, orally active STAT3 dimerization inhibitor. STX-0119 inhibits STAT3 transcription with an IC50 of 74 μM.Fórmula:C22H14N4O3Pureza:99.42%Forma y color:SolidPeso molecular:382.37Ref: TM-T60160
5mg64,00€10mg92,00€25mg177,00€50mg283,00€100mg425,00€500mgA consultar1mL*10mM (DMSO)64,00€LY900009
CAS:LY900009 is a small molecule inhibitor of Notch signalling via selective inhibition of the γ-secretase protein.Fórmula:C23H27N3O4Pureza:97.07%Forma y color:SolidPeso molecular:409.48Ref: TM-T9015
1mg38,00€5mg85,00€10mg118,00€25mg207,00€50mg306,00€100mg444,00€200mg622,00€1mL*10mM (DMSO)93,00€JAK-IN-11
CAS:JAK-IN-11 (R-348) is a potent and selective inhibitor of JAK, has the potential for the skin disorders treatment.Fórmula:C23H22FN5O4SPureza:99.57%Forma y color:SolidPeso molecular:483.52CWP232228
CAS:CWP232228 is a selective Wnt/β-catenin pathway inhibitor targeting β-catenin/TCF binding, halting breast/liver CSC growth and metastasis safely.Fórmula:C33H34N7Na2O7PPureza:96.13%Forma y color:SolidPeso molecular:717.63GSK-3 Inhibitor XIII
CAS:GSK-3 InhibitorXIII, an ATP-competitive GSK-3 inhibitor (Ki: 24 nM), can be used to study diabetes and obesity.Fórmula:C18H15N5Pureza:100% - 98.57%Forma y color:SolidPeso molecular:301.35SJ000291942
CAS:SJ000291942 is an activator of the canonical bone morphogenetic proteins (BMP) signaling pathway.Fórmula:C16H15FN2O4Pureza:99.66%Forma y color:SolidPeso molecular:318.3
