Receptor de efrina
Los inhibidores de los receptores de efrinas (Eph) están dirigidos a los receptores Eph, una familia de tirosina quinasas receptoras que interactúan con ligandos de efrinas unidos a la membrana. La señalización de efrinas es crucial para la posición celular, el patrón de los tejidos y la angiogénesis. La desregulación de esta vía está implicada en el cáncer, enfermedades neurodegenerativas y trastornos del desarrollo. En CymitQuimica, ofrecemos inhibidores de los receptores de efrinas para apoyar su investigación en biología del desarrollo, oncología y neurobiología.
Productos de "Receptor de efrina"
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Hay 15 productos en esta categoría.
UniPR1449
UniPR1449 is an EphA2 receptor antagonist with a KD of 3.8±2.4 μM, which is significant in cancer pathophysiology [1].Pureza:98%Forma y color:Odour SolidTesevatinib
CAS:Tesevatinib (XL-647) is an oral, multi-targeted tyrosine kinase inhibitor.Cost-effective and quality-assured.Fórmula:C24H25Cl2FN4O2Pureza:97.89% - 97.89%Forma y color:SolidPeso molecular:491.39Ref: TM-TQ0166
1mg107,00€2mg156,00€5mg236,00€10mg457,00€25mg750,00€50mg1.026,00€1mL*10mM (DMSO)255,00€JI-101
CAS:JI-101 (CGI-1842) is an oral multi-kinase inhibitor that targets VEGFR-2, PDGFR-β, and EphB4.Fórmula:C22H20BrN5O2Pureza:99.35% - 99.41%Forma y color:SolidPeso molecular:466.33UniPR1447
CAS:UniPR1447 is a dual antagonist for both EphA2 and EphB2 receptors, exhibiting an IC50 value of 6.6 μM against EphA2-ephrin-A1 binding [1].Fórmula:C36H50N2O4Pureza:98%Forma y color:SolidPeso molecular:574.79AWL-II-38.3
CAS:AWL-II-38.3 is a highly potent EphA3 inhibitor with potent kinase inhibitory activity against EphA3.Cost-effective and quality-assured.Fórmula:C23H18F3N5O3Pureza:99.87% - 99.87%Forma y color:SolidPeso molecular:469.42Ref: TM-T38511
1mg81,00€5mg170,00€10mg264,00€25mg543,00€50mg780,00€100mg1.074,00€500mg2.167,00€1mL*10mM (DMSO)177,00€ALW-II-41-27
CAS:ALW-II-41-27 (Eph receptor tyrosine kinase inhibitor), an Eph receptor tyrosine kinase inhibitor, is used for cancer therapy.Fórmula:C32H32F3N5O2SPureza:97.01% - 99.52%Forma y color:SolidPeso molecular:607.69Ref: TM-T4344
1mg69,00€2mg97,00€5mg170,00€10mg264,00€25mg437,00€50mg640,00€100mg910,00€1mL*10mM (DMSO)240,00€123C4
CAS:123C4 is a potent, selective and competitive agonist of the receptor tyrosine kinase EPHA4 (Ki=0.65 μM)[1].Fórmula:C43H47ClN8O6Pureza:98.94%Forma y color:SolidPeso molecular:807.34Ref: TM-TP1561
1mg144,00€5mg311,00€10mg512,00€25mg815,00€50mg1.093,00€100mg1.473,00€1mL*10mM (DMSO)507,00€Ehp-inhibitor-2
CAS:Ehp-inhibitor-2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors.Fórmula:C17H13N5OPureza:98.02%Forma y color:SolidPeso molecular:303.32Ref: TM-T5452
1mg47,00€2mg58,00€5mg87,00€10mg153,00€25mg249,00€50mg369,00€100mg545,00€1mL*10mM (DMSO)97,00€ALW-II-49-7
CAS:ALW-II-49-7 is a selective and potent inhibitor of EphB2 kinase with an EC50 value of 40 nM in cell.Fórmula:C21H17F3N4O2Pureza:99.84%Forma y color:SoildPeso molecular:414.38Ref: TM-T67736
1mg71,00€5mg166,00€10mg243,00€25mg439,00€50mg647,00€100mg920,00€500mg1.853,00€1mL*10mM (DMSO)177,00€UniPR505
CAS:UniPR505 is a potent EphA2 antagonist (IC50: 0.95 µM), a novel 3α-carbamoyloxy derivative with antiangiogenic properties.Fórmula:C39H57N3O5Pureza:99.23%Forma y color:SolidPeso molecular:647.89LDN-211904 oxalate
CAS:LDN-211904 oxalate (LDN211904 oxalate) is a selective and efficient EphB3 inhibitor with antitumor activity, useful in neurodegenerative disease research.Fórmula:C21H21ClN4O5Pureza:99.87%Forma y color:SolidPeso molecular:444.87Eph inhibitor 2
CAS:Eph inhibitor 2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors.Fórmula:C18H15N5OPureza:99.01%Forma y color:SolidPeso molecular:317.34Ref: TM-T5451
1mg95,00€2mg125,00€5mg188,00€10mg284,00€25mg515,00€50mg742,00€100mg1.035,00€500mg2.080,00€1mL*10mM (DMSO)187,00€NVP-BHG712
CAS:NVP-BHG712 is a specific EphB4 inhibitor with ED50 of 25 nM that discriminates between VEGFR and EphB4 inhibition; also shows activity against c-Raf, c-Src andFórmula:C26H20F3N7OPureza:97.32%Forma y color:SolidPeso molecular:503.48Ref: TM-T6348
1mg35,00€5mg79,00€10mg111,00€25mg212,00€50mg393,00€100mg587,00€200mg833,00€1mL*10mM (DMSO)88,00€UniPR500
CAS:UniPR500, a derivative of UniPR129, is a competitive antagonist for the EphA2 receptor, with a Ki of 0.78 μM. It reduces the binding of biotinylated Ephrin-A1 to EphA2 in a dose-dependent manner, exhibiting an IC50 value of 1.1 μM.Fórmula:C36H51N3O4Forma y color:SolidPeso molecular:589.808NVP-BHG712 isomer
CAS:NVP-BHG712 isomer shows conserved non-bonded binding to EPHA2 and EPHB4.Fórmula:C26H20F3N7OPureza:99.14%Forma y color:SolidPeso molecular:503.48Ref: TM-T19487
1mg43,00€2mg56,00€5mg88,00€10mg150,00€25mg259,00€50mg376,00€100mg560,00€1mL*10mM (DMSO)87,00€
