c-Fms
Los inhibidores de c-Fms se dirigen al receptor del factor estimulante de colonias-1 (c-Fms), una tirosina quinasa involucrada en la regulación de los macrófagos y otras células inmunitarias. La señalización de c-Fms juega un papel en la proliferación, diferenciación y supervivencia de estas células. La desregulación de c-Fms está asociada con enfermedades como el cáncer, condiciones inflamatorias y osteoporosis. En CymitQuimica, ofrecemos inhibidores de c-Fms para apoyar su investigación en inmunología, oncología y enfermedades inflamatorias.
Productos de "c-Fms"
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Plonmarlimab
CAS:Plonmarlimab(TJ003234) is an anti-GM-CSF monoclonal antibody with potential antiviral activity for the study of immune disorders and novel coronavirus infectionForma y color:LiquidKi20227
CAS:Ki-20227 is a specific c-Fms tyrosine kinase(CSF1R) inhibitor (IC50: 2 nM).Fórmula:C24H24N4O5SPureza:97.16% - 99.37%Forma y color:SolidPeso molecular:480.54Ref: TM-T4315
1mg47,00€5mg96,00€10mg154,00€25mg283,00€50mg464,00€100mg740,00€200mg1.008,00€1mL*10mM (DMSO)96,00€Dovitinib
CAS:Dovitinib is an orally active, multi-targeted tyrosine kinase (RTK) inhibitor with anti-tumor effects.Cost-effective and quality-assured.Fórmula:C21H21FN6OPureza:99.66% - 99.78%Forma y color:SolidPeso molecular:392.43Ref: TM-T6289
5mg47,00€10mg70,00€25mg126,00€50mg202,00€100mg328,00€200mg490,00€500mg783,00€1mL*10mM (DMSO)50,00€CSF1R Protein, Human, Recombinant (His & Avi)
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:57.4 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.Nampt-IN-1
CAS:Nampt-IN-1 (LSN3154567) (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.Fórmula:C20H25N3O5SPureza:96.82% - 99.4%Forma y color:SolidPeso molecular:419.49Ref: TM-T4376
1mg39,00€2mg52,00€5mg84,00€10mg137,00€25mg259,00€50mg432,00€100mg638,00€1mL*10mM (DMSO)92,00€Anumigilimab
CAS:Anumigilimab (CSL-324) is a fully human therapeutic anti-G-CSFR antibody with potential anti-tumor activity for the study of inflammation.Pureza:95.75% (SEC-HPLC) - 98.43% (SEC-HPLC)Forma y color:LiquidPeso molecular:143.86 kDaPexidartinib
CAS:Pexidartinib (PLX-3397) is a capsule formulation containing a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potentialFórmula:C20H15ClF3N5Pureza:98.34% - 99.51%Forma y color:SolidPeso molecular:417.81Ref: TM-T2115
5mg48,00€10mg62,00€25mg95,00€50mg120,00€100mg154,00€200mg202,00€500mg350,00€1mL*10mM (DMSO)52,00€Chiauranib
CAS:Chiauranib, a potent anticancer agent, inhibits angiogenesis kinases (VEGFR1-3, PDGFRα, c-Kit), Aurora B, and CSF1R with IC50 values of 1-9 nM.Fórmula:C27H21N3O3Pureza:96.25%Forma y color:SolidPeso molecular:435.47Ref: TM-T35570
1mg90,00€5mg187,00€10mg305,00€25mg520,00€50mg748,00€100mg1.026,00€1mL*10mM (DMSO)215,00€PF 477736
CAS:PF 477736 (PF-736,PF-00477736) is a specifc, effective and ATP-competitive Chk1 inhibitor (Ki: 0.49 nM ) and also inhibits FGFR3, Aurora-A, VEGFR2, Flt3, Fms (Fórmula:C22H25N7O2Pureza:98.34% - 99.62%Forma y color:SolidPeso molecular:419.48CSF1R Protein, Human, Recombinant (His & Avi), Biotinylated
M-CSFR/CSF1R/CD115 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag.Forma y color:Lyophilized PowderPeso molecular:57.4 kDa (predicted). Due to glycosylation, the protein migrates to 75-105 kDa based on Tris-Bis PAGE result.c-Fms-IN-14
CAS:c-Fms-IN-14 (Example 76) is a potent inhibitor of the c-Fms kinase with an IC50 of 4 nM, utilized in cancer and autoimmune disease research [1].Fórmula:C26H24N6OPureza:98%Forma y color:SolidPeso molecular:436.51PRN1371
CAS:PRN1371 is a specific and potent FGFR1-4 and CSF1R inhibitor (IC50s: 0.6/1.3/4.1/19.3/8.1 nM for FGFR1/2/3/4 and CSF1R).Fórmula:C26H30Cl2N6O4Pureza:98.65%Forma y color:SolidPeso molecular:561.46Ref: TM-TQ0015
1mg81,00€2mg105,00€5mg170,00€10mg305,00€25mg520,00€50mg748,00€100mg1.026,00€1mL*10mM (DMSO)212,00€Sotuletinib
CAS:Sotuletinib (BLZ945) is an orally active, effective and specific CSF-1R inhibitor, >1000-fold selective against its closest receptor tyrosine kinase homologs.Fórmula:C20H22N4O3SPureza:97.43% - 99.82%Forma y color:SolidPeso molecular:398.48Ref: TM-T6119
1mg37,00€5mg79,00€10mg111,00€25mg172,00€50mg216,00€100mg378,00€500mg868,00€1mL*10mM (DMSO)87,00€CSF1R-IN-2
CAS:CSF1R-IN-2 is an oral-active SRC, MET and c-FMS inhibitor (IC50s: 0.12 nM, 0.14 nM and 0.76 nM for SRC, MET and c-FMS respectively).Fórmula:C20H20FN7O2Pureza:99.29%Forma y color:SolidPeso molecular:409.42Pyrithyldione
CAS:Pyrithyldione is a sedative-hypnotic agent known to potentially induce agranulocytosis.Fórmula:C9H13NO2Forma y color:SolidPeso molecular:167.21Anti-CSF1R Antibody (2I506)
Anti-CSF1R Antibody (2I506) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (2I506) can be used in ELISA.Forma y color:Odour LiquidcFMS Receptor Inhibitor II
CAS:cFMS Receptor Inhibitor II is a CSF1R kinase inhibitorFórmula:C23H20N4OPureza:99.80%Forma y color:SolidPeso molecular:368.43Ref: TM-T5586
1mg49,00€2mg65,00€5mg97,00€10mg154,00€25mg255,00€50mg376,00€100mg547,00€1mL*10mM (DMSO)106,00€Anti-CSF1R Antibody (4Y587)
Anti-CSF1R Antibody (4Y587) is a Mouse antibody targeting CSF1R. Anti-CSF1R Antibody (4Y587) can be used in FCM.Forma y color:Odour LiquidOSI-930
CAS:OSI-930 is an oral c-Kit/VEGFR-2 inhibitor targeting tumor growth and angiogenesis.Fórmula:C22H16F3N3O2SPureza:99.67%Forma y color:SolidPeso molecular:443.44Ref: TM-T2624
1mg51,00€5mg93,00€10mg144,00€25mg263,00€50mg424,00€100mg612,00€200mg873,00€1mL*10mM (DMSO)97,00€Enrupatinib
CAS:Enrupatinib is an inhibitor of the colony stimulating factor 1 receptor (CSF1R), exhibiting antitumor activity.Fórmula:C27H26N6O3Forma y color:SolidPeso molecular:482.53
