c-Fms
Los inhibidores de c-Fms se dirigen al receptor del factor estimulante de colonias-1 (c-Fms), una tirosina quinasa involucrada en la regulación de los macrófagos y otras células inmunitarias. La señalización de c-Fms juega un papel en la proliferación, diferenciación y supervivencia de estas células. La desregulación de c-Fms está asociada con enfermedades como el cáncer, condiciones inflamatorias y osteoporosis. En CymitQuimica, ofrecemos inhibidores de c-Fms para apoyar su investigación en inmunología, oncología y enfermedades inflamatorias.
Productos de "c-Fms"
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Anti-CSF1R Antibody (7V18)
Anti-CSF1R Antibody (7V18) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (7V18) can be used in ELISA.Forma y color:Odour LiquidSotuletinib dihydrochloride
CAS:Sotuletinib (BLZ945) dihydrochloride is an orally administered, blood-brain barrier-permeable inhibitor specifically targeting CSF1-R with an IC50 of 1 nM.Fórmula:C20H24Cl2N4O3SPureza:98%Forma y color:SolidPeso molecular:471.4c-Fms-IN-9
CAS:c-Fms-IN-9 inhibits c-FMS/uFMS and uKIT with IC50 <0.01μM and 0.1-1μM, from patent WO2014145023A1.Fórmula:C21H23N7O2Pureza:98%Forma y color:SolidPeso molecular:405.45cFMS Receptor Inhibitor IV
CAS:cFMS Receptor Inhibitor IV is an inhibitor of c-Fms tyrosine kinase.Fórmula:C22H26N4O2Pureza:99.73%Forma y color:SolidPeso molecular:378.47AZ304
CAS:AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits BRAF (WT), BRAF (V600E), and wild type CRAF (IC50s: 79/38/68 nM).Fórmula:C27H25N5O2Pureza:99.82%Forma y color:SolidPeso molecular:451.52CSF1R Protein (Met1-Glu512), Human, Recombinant (His)
CSF1R Protein (Met1-Glu512), Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag.Pureza:SDS-PAGE: 97.7%; SEC-HPLC: 99.7%Forma y color:Lyophilized PowderPeso molecular:56 kDa (predicted); 85-95 kDa (reducing condition, due to glycosylation)GW786034B
CAS:Pazopanib HCl (Votrient) inhibits VEGFR1-3, PDGFR, FGFR, c-Kit, c-Fms with IC50 range 10-146 nM in cell-free assays.Fórmula:C21H23N7O2S·HClPureza:99.87%Forma y color:SolidPeso molecular:473.98Ref: TM-T6930
10mg52,00€25mg90,00€50mg96,00€100mg140,00€200mg229,00€500mg359,00€1mL*10mM (DMSO)52,00€Vimseltinib
CAS:Vimseltinib (DCC-3014) is a c-FMS (CSF-IR) and c-Kit dual inhibitor (IC50s: <0.01 μM and 0.1-1 μM).Fórmula:C23H25N7O2Pureza:99.05% - 99.57%Forma y color:SolidPeso molecular:431.49Ref: TM-T10652
1mg92,00€5mg188,00€10mg311,00€25mg533,00€50mg727,00€100mg938,00€1mL*10mM (DMSO)215,00€Linifanib
CAS:Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) andFórmula:C21H18FN5OPureza:98% - 98.24%Forma y color:SolidPeso molecular:375.4Ref: TM-T2514
5mg50,00€10mg85,00€25mg126,00€50mg188,00€100mg274,00€200mg505,00€500mg815,00€1mL*10mM (DMSO)52,00€c-Fms-IN-3
CAS:c-Fms-IN-3 is a novel inhibitor of the c-FMS and can be used in studies about antirheumatic and anti-inflammatory diseases.Fórmula:C23H30N6OPureza:99.92%Forma y color:SolidPeso molecular:406.52Ref: TM-T10649
1mg50,00€5mg111,00€10mg170,00€25mg279,00€50mg378,00€100mg552,00€1mL*10mM (DMSO)116,00€CSF1R Protein, Human, Recombinant (Domain I&II&III, His)
CSF1R Protein, Human, Recombinant (Domain I&II&III, His) is expressed in HEK293 mammalian cells with His tag.Forma y color:Lyophilized PowderPeso molecular:31.1 kDa (predicted)Anti-CSF1R Antibody (5C535)
Anti-CSF1R Antibody (5C535) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (5C535) can be used in ELISA.Forma y color:Odour LiquidGW2580
CAS:GW2580 (SC-203877) is a specific, oral-bioavailable CSF-1R inhibitor for c-FMS.Fórmula:C20H22N4O3Pureza:100% - 99.86%Forma y color:SolidPeso molecular:366.41c-Fms-IN-1
CAS:c-Fms-IN-1 is an inhibitor of c-FMS kinase (IC50 = 0.8 nM).Fórmula:C22H27N5O2Pureza:99.88%Forma y color:SolidPeso molecular:393.48CSF1R-IN-3
CAS:CSF1R-IN-3 is an orally effective CSF-1R inhibitor with an IC50 value of 2.1 nM.Fórmula:C30H38N8O4Pureza:97.31%Forma y color:SolidPeso molecular:574.67Ref: TM-T64066
1mg106,00€5mg259,00€10mg378,00€25mg702,00€50mg1.026,00€100mg1.473,00€1mL*10mM (DMSO)325,00€CSF1R-IN-1
CAS:CSF1R-IN-1 is a CSF1R inhibitor with IC50 of 0.5 nM.Fórmula:C25H20F3N5O2Pureza:97.02% - 98.56%Forma y color:SolidPeso molecular:479.45Ref: TM-T10894
1mg94,00€5mg210,00€10mg325,00€25mg550,00€50mg787,00€100mg1.093,00€200mg1.454,00€1mL*10mM (DMSO)230,00€CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated
CSF1R Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag.Forma y color:Lyophilized PowderPeso molecular:83.04 kDa (predicted); 110.87 kDa (reducing conditions)Anti-CSF1R Antibody (1R707)
Anti-CSF1R Antibody (1R707) is a Rabbit antibody targeting CSF1R. Anti-CSF1R Antibody (1R707) can be used in ELISA.Forma y color:Odour LiquidAZD7507
CAS:AZD7507 is a CSF-1R inhibitor with an IC50 of 32 nM. AZD7507 has antitumor activity.Fórmula:C23H27FN6O3Pureza:98.01% - 99.09%Forma y color:SolidPeso molecular:454.5Ref: TM-T14380
1mg52,00€5mg116,00€10mg170,00€25mg305,00€50mg442,00€100mg615,00€200mg832,00€1mL*10mM (DMSO)134,00€IACS-9439
CAS:IACS-9439 is a potent, selective, and orally active inhibitor of CSF1R, exhibiting a K(i) of 1 nM.Fórmula:C23H26ClN7O3SPureza:98%Forma y color:SolidPeso molecular:516.02
