PDGFR
Los inhibidores del receptor del factor de crecimiento derivado de plaquetas (PDGFR) son compuestos que bloquean la señalización del PDGFR, un receptor involucrado en el crecimiento celular, la proliferación y la angiogénesis. El PDGFR desempeña un papel significativo en el desarrollo de los vasos sanguíneos que abastecen a los tumores. Inhibir el PDGFR puede, por lo tanto, prevenir la angiogénesis, lo que convierte a estos inhibidores en herramientas valiosas en la terapia contra el cáncer. En CymitQuimica, ofrecemos una selección de inhibidores de PDGFR de alta calidad para apoyar su investigación en oncología, biología vascular y angiogénesis.
Productos de "PDGFR"
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Lenvatinib mesylate
CAS:Lenvatinib mesylate (E7080 (mesylate)) is an oral and multi-targeted inhibitor of VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, with potent antitumor activities.Fórmula:C22H23ClN4O7SPureza:99.03% - 99.79%Forma y color:SolidPeso molecular:522.96Imatinib Mesylate
CAS:Fórmula:C29H31N7O·CH4O3SPureza:>98.0%(HPLC)Forma y color:White to Light yellow powder to crystalPeso molecular:589.72Imatinib
CAS:Fórmula:C29H31N7OPureza:>98.0%(HPLC)Forma y color:White to Light yellow to Light orange powder to crystalPeso molecular:493.62Tyrphostin RG 13022
CAS:Fórmula:C16H14N2O2Pureza:>98.0%(GC)Forma y color:White to Yellow to Green powder to crystalPeso molecular:266.30Anti-PDGFRB Antibody-APC (1A610)
Anti-PDGFRB Antibody-APC (1A610) is a APC-conjugated Mouse antibody targeting PDGFRB. Anti-PDGFRB Antibody-APC (1A610) can be used in FCM.Forma y color:Odour LiquidCP-673451
CAS:CP-673451 is a specific inhibitor of PDGFRα/β (IC50: 10/1 nM) with antiangiogenic and antitumor activity and the selectivity is higher 450-fold than otherFórmula:C24H27N5O2Pureza:99.62% - 99.88%Forma y color:SolidPeso molecular:417.5Ref: TM-T6091
1mg52,00€2mg66,00€5mg96,00€10mg180,00€25mg354,00€50mg540,00€100mg778,00€500mg1.605,00€1mL*10mM (DMSO)114,00€Nintedanib esylate
CAS:Nintedanib esylate (BIBF 1120 esylate) is a potent triple angiokinase inhibitor for VEGFR1/2/3, FGFR1/2/3 and PDGFRα/βFórmula:C31H33N5O4·C2H6O3SPureza:99.43% - 99.96%Forma y color:SolidPeso molecular:649.76Ref: TM-T5001
5mg43,00€10mg57,00€25mg71,00€50mg85,00€100mg105,00€200mg164,00€500mg316,00€1mL*10mM (DMSO)63,00€AG 1295
CAS:AG 1295 is a selective PDGFR tyrosine-kinase inhibitor; it blocks PDGFR autophosphorylation without affecting EGF receptor.Fórmula:C16H14N2Pureza:99.64%Forma y color:SolidPeso molecular:234.3JNJ-10198409
CAS:JNJ-10198409: selective ATP competitive PDGF-RTK inhibitor; IC50: PDGFR-β 4.2 nM, PDGFR-α 45 nM; antiangiogenic & antiproliferative.Fórmula:C18H16FN3O2Pureza:98.51%Forma y color:SolidPeso molecular:325.34Ref: TM-T15616
1mg34,00€5mg96,00€10mg129,00€25mg210,00€50mg309,00€100mg442,00€200mg620,00€1mL*10mM (DMSO)104,00€Dovitinib lactate
CAS:Dovitinib lactate (TKI-258 lactate)(TKI258) lactate is a potent inhibitor of fibroblast growth factor receptor 3 (FGFR3) (IC50 :5 nM).Fórmula:C24H27FN6O4Pureza:98.44% - 99.54%Forma y color:SolidPeso molecular:482.51Ref: TM-T7104
5mg51,00€10mg79,00€25mg129,00€50mg213,00€100mg358,00€200mg535,00€500mg843,00€1mL*10mM (DMSO)57,00€TCS 359
CAS:Fórmula:C18H20N2O4SPureza:>98.0%(HPLC)Forma y color:Light yellow to Brown powder to crystalPeso molecular:360.43Avapritinib
CAS:Avapritinib (BLU-285) is a selective, highly potent, and orally active inhibitor of KIT and PDGFRA activation loop mutant kinases.Cost-effective and quality-assured.Fórmula:C26H27FN10Pureza:96.59% - 99.7%Forma y color:SolidPeso molecular:498.56Ref: TM-T5109
1mg88,00€5mg187,00€10mg305,00€25mg520,00€50mg748,00€100mg1.026,00€500mg2.072,00€1mL*10mM (DMSO)205,00€Sennoside B
CAS:Sennoside B is an anthranoid. Anthranoid derivatives are used all over the world as a treatment for constipation.Fórmula:C42H38O20Pureza:92.85% - 98.92%Forma y color:Light Yellow CrystalPeso molecular:862.74PDGFRB Protein, Human, Recombinant
PDGFRB Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 56.2 kDa and the accession number is P09619-1.Forma y color:Lyophilized PowderPeso molecular:56.2 kDa (predicted)SU14813
CAS:SU14813: inhibits multiple kinases (VEGFR2, VEGFR1, PDGFRβ, KIT) with IC50s of 50, 2, 4, 15 nM; antiangiogenic and antitumor.Fórmula:C23H27FN4O4Pureza:99.72%Forma y color:SolidPeso molecular:442.48Tyrphostin AG1296
CAS:Tyrphostin AG1296 (Tyrphostin AG 1296) is an inhibitor of PDGFR with IC50 of 0.3-0.5 μM, no activity to EGFR.Fórmula:C16H14N2O2Pureza:99.66% - 99.68%Forma y color:SolidPeso molecular:266.29Ref: TM-T6711
2mg40,00€5mg58,00€10mg90,00€25mg180,00€50mg279,00€100mg411,00€200mg585,00€1mL*10mM (DMSO)81,00€Flumatinib
CAS:Flumatinib (HHGV678) is an orally bioavailable tyrosine kinase inhibitor flumatinib, with potential antineoplastic activity.Fórmula:C29H29F3N8OPureza:99.52% - 99.95%Forma y color:SolidPeso molecular:562.59Ref: TM-T4320
1mg35,00€5mg66,00€10mg87,00€25mg127,00€50mg163,00€100mg273,00€200mg409,00€500mg677,00€1mL*10mM (DMSO)87,00€Linifanib
CAS:Fórmula:C21H18FN5OPureza:>95.0%(HPLC)(qNMR)Forma y color:White to Light yellow powder to crystalPeso molecular:375.41AG-1296
CAS:Fórmula:C16H14N2O2Pureza:>98.0%(GC)Forma y color:White to Orange to Green powder to crystalPeso molecular:266.30Toceranib
CAS:Toceranib phosphate, orally active, inhibits RTK, PDGFR, VEGFR, Kit; Kis 5 nM PDGFRβ, 6 nM KDR; has antitumor effects.Fórmula:C22H25FN4O2Pureza:97.14%Forma y color:SolidPeso molecular:396.46
