Receptor TAM
Los inhibidores de los receptores TAM están dirigidos a la familia de receptores tirosina quinasa TAM, que incluye Tyro3, Axl y Mer. Estos receptores están involucrados en la regulación de las respuestas inmunitarias, la supervivencia celular y la eliminación de células apoptóticas. La desregulación de los receptores TAM está implicada en el cáncer, enfermedades autoinmunes e inflamación crónica. En CymitQuimica, ofrecemos inhibidores de los receptores TAM para apoyar su investigación en inmunología, oncología e inflamación.
Productos de "Receptor TAM"
Ordenar por
NPS-1034
CAS:NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.Fórmula:C31H23F2N5O3Pureza:98.48%Forma y color:SolidPeso molecular:551.54CEP-40783
CAS:CEP-40783 (RXDX-106) is an effective, specific and orally active AXL/c-Met inhibitor (IC50: 7/12 nM). It also inhibits MER and TYRO3 (IC50: 29/19 nM).Fórmula:C31H26F2N4O6Pureza:99.45% - 99.64%Forma y color:SolidPeso molecular:588.56RU-301
CAS:RU-301 is a novel pan-tam inhibitorFórmula:C21H19F3N4O4SPureza:98.87%Forma y color:SolidPeso molecular:480.46Ref: TM-T7425
1mg103,00€5mg235,00€10mg364,00€25mg620,00€50mg848,00€100mg1.121,00€1mL*10mM (DMSO)255,00€Cabozantinib
CAS:Cabozantinib (XL184) is a multi-targeted tyrosine kinase receptor inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt3 (IC50=0.035/1.3/4.6/7/11.3 nM).Fórmula:C28H24FN3O5Pureza:99.59% - 99.88%Forma y color:SolidPeso molecular:501.51UNC2250
CAS:UNC2250 is an effective and specific Mer inhibitor (IC50=1.7 nM).Fórmula:C24H36N6O2Pureza:98.88% - 99.35%Forma y color:SolidPeso molecular:440.58ONO-7475
CAS:ONO-7475 is an inhibitor with high specificity for anexelekto and MER tyrosine kinaseFórmula:C32H26N4O6Pureza:98.74%Forma y color:SolidPeso molecular:562.57R916562
CAS:R916562 is an orally active and selective Axl/VEGF-R2 inhibitor with IC50s of 136 nM and 24 nM, respectively. R916562 has anti-angiogenesis and anti-metastasis.Fórmula:C26H30ClN9SPureza:98%Forma y color:SolidPeso molecular:536.09Axl-IN-16
Axl-IN-16, a dual Axl/HIF inhibitor, promotes Flammulina velutipes fruiting body formation and suppresses hypoxia-inducible factor activity along with receptorFórmula:C14H19ClO8Pureza:98%Forma y color:SolidPeso molecular:350.75Cabozantinib hydrochloride
CAS:Cabozantinib hydrochloride (XL184) is a potent pan-tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl, and Flt4 (IC50s: 0.035, 1.3, 4.6, 7 and 6Fórmula:C28H25ClFN3O5Pureza:99.97%Forma y color:SolidPeso molecular:537.96Ref: TM-T5164
1mg44,00€2mg55,00€5mg69,00€10mg97,00€25mg169,00€50mg248,00€100mg349,00€200mg568,00€500mg908,00€Gilteritinib
CAS:Gilteritinib (ASP2215) is a potent inhibitor at the FMS-related tyrosine kinase 3 (FLT3) and AXL tyrosine kinase receptors (IC50 = 0.29 nM and <1 nM,Fórmula:C29H44N8O3Pureza:97.75% - 99.74%Forma y color:SolidPeso molecular:552.71Ref: TM-T4409
1g1.359,00€1mg40,00€2mg55,00€5mg89,00€10mg120,00€25mg187,00€50mg276,00€100mg434,00€500mg1.008,00€2-D08
CAS:2-D08 is a synthetic flavone that inhibits sumoylation, also inhibits Axl with an IC50 of 0.49 nM.2-D08 showed anti-aggregatory and neuroprotective effect.Fórmula:C15H10O5Pureza:98.58% - 98.95%Forma y color:SolidPeso molecular:270.24
