CaSR
El receptor sensible al calcio (CaSR) es un GPCR que juega un papel vital en el mantenimiento de la homeostasis del calcio al regular la secreción de la hormona paratiroidea y la reabsorción de calcio en los riñones. El CaSR también está involucrado en varios otros procesos fisiológicos, incluido el metabolismo óseo y la función vascular. Los moduladores de CaSR se utilizan en el tratamiento de afecciones como el hiperparatiroidismo, la osteoporosis y las enfermedades cardiovasculares. En CymitQuimica, ofrecemos una selección de moduladores de CaSR de alta calidad para apoyar su investigación en el metabolismo del calcio, endocrinología y salud ósea.
Productos de "CaSR"
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Hay 20 productos en esta categoría.
Strontium ranelate
CAS:Strontium ranelate (S12911), a strontium (II) salt of the ranelic acid, is a medication for osteoporosis and can slow the course of osteoarthritis of the knee.Fórmula:C12H6N2O8S·2SrPureza:98.97%Forma y color:Crystalline SolidPeso molecular:513.49Calindol hydrochloride
CAS:Calindol (hydrochloride) is a positive allosteric modulator (PAM) of calcimimetic calcium-sensing receptor (CaSR) with an EC50 of 132 nM.Fórmula:C21H21ClN2Pureza:99.47%Forma y color:SolidPeso molecular:336.86Cinacalcet hydrochloride
CAS:Cinacalcet hydrochloride (AMG-073 hydrochloride) is a naphthalene derivative and CALCIMIMETIC AGENT that increases the sensitivity of PARATHYROID GLAND calcium-Fórmula:C22H23ClF3NPureza:99.9% - 99.94%Forma y color:Off-White To Tan SolidPeso molecular:393.87Ref: TM-T2406
10mg50,00€25mg70,00€50mg88,00€100mg144,00€200mg185,00€500mg309,00€1mL*10mM (DMSO)52,00€AC265347
CAS:AC265347 is a potent calcium-sensitive receptor (CaSR) agonist and ago-PAM orthosteric modulator with antitumour activity for the study of neuroblastoma.Fórmula:C17H17NOSPureza:100%Forma y color:SolidPeso molecular:283.39Ronacaleret HCl
CAS:Ronacaleret HCl (SB-751689) is a small molecule CaSR antagonist for the treatment of endocrine and metabolic diseases, skin and musculoskeletal disorders.Fórmula:C25H32ClF2NO4Pureza:99.58%Forma y color:SolidPeso molecular:483.98Etelcalcetide hydrochloride
CAS:Etelcalcetide HCl, a synthetic peptide modulator of CaSR, lowers PTH in dialysis patients with secondary hyperparathyroidism.Fórmula:C38H73N21O10S2HClPureza:100%Forma y color:SolidPeso molecular:1353.33SB-423562
CAS:SB-423562 is a calcium-sensing receptor (CaSR) antagonist and can be used in studies about osteoporosis.Fórmula:C26H32N2O4Pureza:98.64%Forma y color:SolidPeso molecular:436.54Ref: TM-T12846
1mg39,00€5mg85,00€10mg126,00€25mg221,00€50mg338,00€100mg467,00€200mg640,00€1mL*10mM (DMSO)94,00€Strontium chloride
CAS:Strontium chloride is an agonist of Calcium sensing receptor (CaSR) and directly affects C-type nerve fibers.Fórmula:Cl2SrPureza:98%Forma y color:White Solid CrystallinePeso molecular:158.52Poly-D-lysine hydrobromide (MW 30000-70000)
CAS:Poly-D-lysine hydrobromide (MW 30000-70000) (Poly-D-lysine HBr) is a peptide CaSR agonist that removes proteinase K-resistant PrP from SN56 neuroblastoma cells.Fórmula:(C6H14N2O2)x·xHBrForma y color:SolidPeso molecular:227.102Tecalcet Hydrochloride
CAS:Tecalcet Hydrochloride, an allosteric CaSR modulator, enhances extracellular Ca2+ sensitivity.Fórmula:C18H23Cl2NOPureza:99.44%Forma y color:SolidPeso molecular:340.29Ref: TM-T13918
2mg35,00€5mg49,00€10mg75,00€25mg155,00€50mg244,00€100mg354,00€200mgA consultar1mL*10mM (DMSO)50,00€NPS-2143 hydrochloride
CAS:NPS-2143 hydrochloride (NPS-2143 HCL) is a selective potent calcium ion-sensing receptor antagonist.Fórmula:C24H25ClN2O2·HClPureza:99.22% - 99.38%Forma y color:SolidPeso molecular:445.38Ref: TM-T4967
1mg46,00€2mg59,00€5mg92,00€10mg126,00€25mg215,00€50mg339,00€100mg502,00€1mL*10mM (DMSO)90,00€Gadolinium chloride
CAS:Gadolinium chloride is a calcium-sensing receptor (CaSR) agonistFórmula:Cl3GdPureza:98%Forma y color:White Crystalline SolidPeso molecular:263.61Cinacalcet
CAS:Cinacalcet (AMG 073) is an orally active, allosteric Ca receptor (CaR) agonist, treatment of cardiovascular disease .Fórmula:C22H22F3NPureza:99.48%Forma y color:Yellow OilPeso molecular:357.41NPS2390
CAS:NPS2390 is a first generation quinoxaline derivative that acts as a noncompetitive antagonist of mGluR1 and mGluR5 (IC50 of 5.2 and 82 nM, respectively)Fórmula:C19H21N3OPureza:97.13%Forma y color:SolidPeso molecular:307.39γ-Glu-Abu TFA
Gamma-Glu-AbuTFA is the TFA salt form of Gamma-Glu-Abu. This compound acts as an agonist for the calcium sensing receptor (CaSR), activating CaSR in HEK-293 cells with an EC50 of 0.21 μM.Fórmula:C11H17F3N2O7Forma y color:SolidPeso molecular:346.26NPS-2143
CAS:NPS-2143 (SB 262470A) is a novel potent and selective antagonist of Ca(2+) receptor.Fórmula:C24H25ClN2O2Pureza:98.24%Forma y color:SolidPeso molecular:408.92Upacicalcet HCl
Upacicalcet HCl, a calcium mimetic, reduces blood PTH by targeting parathyroid receptors; treats secondary hyperparathyroidism.Fórmula:C11H15Cl2N3O6SPureza:98.56%Forma y color:SoildPeso molecular:388.22Ligustroflavone
CAS:Ligustroflavone (Nuezhenoside) has anti-inflammatory activity.Fórmula:C33H40O18Pureza:98% - 99.92%Forma y color:SolidPeso molecular:724.66H-Glu-Thr-OH
CAS:H-Glu-Thr-OH (L-α-Glutamyl-L-threonine) is a dipeptide composed of two amino acids-glutamic acid (Glu) and threonine (Thr)-linked by a peptide bond and functions as an agonist of the extracellular calcium-sensing receptor (CaSR).Fórmula:C9H16N2O6Forma y color:SolidPeso molecular:248.23Evocalcet
CAS:Evocalcet (KHK7580) has an activating effect on the calcium-sensing receptor (CaSR).Fórmula:C24H26N2O2Pureza:98.88% - 99.68%Forma y color:SolidPeso molecular:374.48
