Receptor de histamina
Los receptores de histamina son GPCR que median los efectos de la histamina, una amina biógena involucrada en las respuestas inmunitarias, la secreción de ácido gástrico y la neurotransmisión. Hay cuatro subtipos de receptores de histamina (H1, H2, H3 y H4), cada uno de los cuales desempeña roles distintos en las reacciones alérgicas, la función gástrica y la actividad del sistema nervioso central. Los antagonistas de los receptores de histamina se utilizan ampliamente en el tratamiento de alergias, úlceras pépticas y mareos por movimiento. En CymitQuimica, ofrecemos una selección integral de moduladores de receptores de histamina de alta calidad para apoyar su investigación en inmunología, gastroenterología y neurofarmacología.
Productos de "Receptor de histamina"
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Proxyfan
CAS:Proxyfan is a high-affinity protean antagonist/agonist of H3 receptors from full agonist to full inverse agonist, depending on given tissue or brain region.Fórmula:C13H16N2OPureza:99.68%Forma y color:SolidPeso molecular:216.28Vapitadine dihydrochloride
CAS:Vapitadine dihydrochloride(R-129160 2HCl) is a novel, potent, selective and non-sedating compound with inhibitory effects on histamine H1.Fórmula:C17H22Cl2N4OPureza:100% - 99.92%Forma y color:SolidPeso molecular:369.29Betahistine
CAS:Betahistine treats vertigo and balance issues in Ménière's disease; it's a histamine analog and H1 receptor agonist.Fórmula:C8H12N2Pureza:97.92% - 99.87%Forma y color:Yellowish Liquid Liquid LiquidPeso molecular:136.19N-Acetylhistamine
CAS:N-Acetylhistamine (N-Omega-acetylhistamine) is a metabolite of histamine.Fórmula:C7H11N3OPureza:97.72%Forma y color:SolidPeso molecular:153.18(R)-(-)-α-Methylhistamine dihydrobromide
CAS:(R)-(-)-α-Methylhistamine dihydrobromide is a potent and selective agonist of H3 histamine receptor( Kd of 50.3 nM).Fórmula:C6H13Br2N3Pureza:98%Forma y color:SolidPeso molecular:287Dimethindene maleate
CAS:Dimethindene maleate (SU 6518) is a histamine H1 antagonist and can be used in studies about the treatment of hypersensitivity reactions, pruritus and rhinitis.Fórmula:C24H28N2O4Pureza:99.87%Forma y color:SolidPeso molecular:408.49Ref: TM-T21472
1mg35,00€5mg74,00€10mg111,00€25mg250,00€50mg329,00€100mg432,00€200mg615,00€1mL*10mM (DMSO)87,00€H4R antagonist 1
CAS:H4R antagonist 1: selective histamine H4R inhibitor, IC50 27 nM, no affinity for H1R, H2R, H3R.Fórmula:C11H11BrN8Forma y color:SolidPeso molecular:335.16H3R antagonist 5
CAS:H3R antagonist 5 (Compound 1b) is a selective inverse agonist of the histamine H3 receptor that can penetrate the blood-brain barrier, with an IC50 of 0.54 nM. It is applicable for research related to the central nervous system.Fórmula:C23H32N2O4Forma y color:SolidPeso molecular:400.511Irdabisant
CAS:Irdabisant (CEP-26401) is an H3R antagonist/inverse agonist, BBB permeable, with cognition-enhancing effects for schizophrenia/cognitive research.Fórmula:C18H23N3O2Pureza:99.77%Forma y color:SolidPeso molecular:313.39Ref: TM-T32191
1mg58,00€5mg134,00€10mg188,00€25mg335,00€50mg470,00€100mg662,00€500mg1.320,00€1mL*10mM (DMSO)93,00€ICI 162,846
CAS:ICI 162,846 is an orally active and potent H2 receptor antagonist that inhibits gastric secretion and may be used in the study of duodenal ulcers.Fórmula:C11H17F3N6OPureza:99.83%Forma y color:SolidPeso molecular:306.29H3 receptor-MO-1
CAS:H3 receptor-MO-1 is a potent modulator of the histamine H3 receptor (H3 receptor) and can be used to study neurodegeneration and cognitive disorders.Fórmula:C20H27N3O2Pureza:99.11%Forma y color:SolidPeso molecular:341.45Pitolisant
CAS:Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human histamine H3 receptor with Ki of 0.16 nM.Fórmula:C17H26ClNOPureza:99.84%Forma y color:SolidPeso molecular:295.85Ref: TM-T60636
5mg48,00€10mg70,00€25mg120,00€50mg188,00€100mg311,00€500mg747,00€1mL*10mM (DMSO)52,00€Olopatadine hydrochloride
CAS:Olopatadine hydrochloride (ALO4943A) is an antihistamine with mast-cell stabilizing properties used as eye drops in the treatment of ALLERGIC CONJUNCTIVITIS.Fórmula:C21H23NO3·HClPureza:99.62% - 99.64%Forma y color:White SolidPeso molecular:373.87Latrepirdine dihydrochloride
CAS:Latrepirdine dihydrochloride (Dimebolin dihydrochloride) is an orally active, and neuroactive antagonist of multiple drug targets.Fórmula:C21H25N3·2HClPureza:98.45%Forma y color:SolidPeso molecular:392.37PF 03654746 FA
PF 03654746 FA is a human histamine receptor H(3) antagonist that can be used to study cognitive impairment and Alzheimer's disease.Fórmula:C19H26F2N2O3Pureza:96.15%Forma y color:SoildPeso molecular:368.42H1R ligand-1
CAS:H1R ligand-1 (Compound fragment 1) is a high-affinity ligand for the human histamine H1 receptor (H1R). It can serve as a scaffold for synthesizing a series of derivatives to investigate H1R binding kinetics.Fórmula:C19H23NOForma y color:SolidPeso molecular:281.392H4R antagonist 2
CAS:H4R Antagonist 2, a potent Furo[3,2-d]pyrimidine derivative, serves as a histamine H4 receptor antagonist and holds potential for research into rheumatoidFórmula:C13H17N5OPureza:98%Forma y color:SolidPeso molecular:259.31TAAR1 agonist 2
CAS:TAAR1 agonist 2 (compound 30), a full agonist at trace amine-associated receptor 1 (TAAR1) (pEC50=7.5), also displays agonistic properties at H1 receptors and activates various muscarinic acetylcholine receptors, including the M2 receptor (pEC50=5). This compound is utilized in researching neuropsychiatric diseases.Fórmula:C9H11NOForma y color:SolidPeso molecular:149.19Dioxopromethazine
CAS:Dioxopromethazine (Dioxoprothazine) is a drug for the treatment of a cough and expectoration. It also can be used in local anesthesia.Fórmula:C17H20N2O2SPureza:98%Forma y color:SolidPeso molecular:316.42JNJ-7777120
CAS:JNJ-7777120 is the first potent and selective non-imidazole histamine H4 receptor antagonist, exhibits >1000-fold selectivity over the other histamin receptors.Fórmula:C14H16ClN3OPureza:99.83% - 99.96%Forma y color:SolidPeso molecular:277.75
