SGLT
Los cotransportadores sodio-glucosa (SGLT) son proteínas de membrana que facilitan la reabsorción de glucosa en los riñones al acoplar el transporte de glucosa con los iones de sodio. Los inhibidores de SGLT son una clase importante de medicamentos utilizados en el tratamiento de la diabetes tipo 2, ya que ayudan a reducir los niveles de glucosa en sangre al prevenir la reabsorción de glucosa en los túbulos renales. Estos inhibidores también están siendo investigados por sus posibles beneficios en la protección cardiovascular y renal. En CymitQuimica, ofrecemos una gama de moduladores de SGLT de alta calidad para apoyar su investigación en diabetes, fisiología renal y trastornos metabólicos.
Productos de "SGLT"
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Ertugliflozin L-pyroglutamic acid
CAS:Ertugliflozin is a potent oral hSGLT2 inhibitor (IC50: 0.877 nM) for type 2 diabetes treatment studies.Fórmula:C27H32ClNO10Pureza:98.71% - 99.84%Forma y color:SolidPeso molecular:566Ref: TM-T15244
5mg47,00€10mg60,00€25mg89,00€50mg96,00€100mg140,00€200mg198,00€500mg340,00€1mL*10mM (DMSO)52,00€Licogliflozin
CAS:Licogliflozin (LIK066) is an inhibitor of sodium-glucose cotransporter (SGLT1 and SGLT2).Fórmula:C23H28O7Pureza:98%Forma y color:SolidPeso molecular:416.46Bexagliflozin
CAS:Bexagliflozin (EGT1442) is a potent, selective sodium glucose co-transporter 2 (SGLT2) inhibitor with IC50 values of 2 nM for human SGLT2.Fórmula:C24H29ClO7Pureza:98.99%Forma y color:SolidPeso molecular:464.94Ref: TM-T7217
1mg71,00€2mg90,00€5mg136,00€10mg197,00€25mg393,00€50mg582,00€100mg830,00€1mL*10mM (DMSO)144,00€Dapagliflozin ((2S)-1,2-propanediol, hydrate)
CAS:Dapagliflozin ((2S)-1,2-propanediol, hydrate) (BMS-512148 (2S)-1,2-propanediol, hydrate) is a selective, orally active inhibitor of the renal sodium-glucose co-Fórmula:C24H35ClO9Pureza:99.88% - 99.94%Forma y color:SolidPeso molecular:502.98KGA-2727
CAS:KGA-2727: potent, selective SGLT1 inhibitor (human Ki 97.4 nM, rat 43.5 nM), with high selectivity over SGLT2 for diabetes treatment.Fórmula:C26H40N4O8Pureza:98.95%Forma y color:SolidPeso molecular:536.62Ref: TM-T15656
1mg120,00€5mg274,00€10mg454,00€25mg750,00€50mg1.026,00€100mg1.406,00€200mg1.890,00€1mL*10mM (DMSO)323,00€T-1095
CAS:T-1095 is an inhibitor of renal glucose reabsorption and the expression of Na+-glucose cotransporters (SGLTs) and facilitative glucose transporter 2 (GLUT2).Fórmula:C26H28O11Pureza:99.56%Forma y color:SolidPeso molecular:516.49Ref: TM-T9590
1mg52,00€2mg74,00€5mg96,00€10mg137,00€25mg217,00€50mg391,00€100mg560,00€1mL*10mM (DMSO)134,00€Sergliflozin etabonate
CAS:Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.Fórmula:C23H28O9Pureza:95.59%Forma y color:SolidPeso molecular:448.46Ref: TM-T28757
1mg185,00€2mg279,00€5mg425,00€10mg625,00€25mg938,00€50mg1.311,00€100mg1.795,00€1mL*10mM (DMSO)490,00€O-Desethyl Dapagliflozin
CAS:O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.Fórmula:C19H21ClO6Pureza:97.09%Forma y color:SolidPeso molecular:380.82Ref: TM-T67849
1mg57,00€5mg120,00€10mg187,00€25mg321,00€50mg470,00€100mg683,00€1mL*10mM (DMSO)135,00€Tofogliflozin (hydrate)
CAS:Tofogliflozin hydrate (CSG-452 hydrate) is a potent and highly specific inhibitor of SGLT2(Ki of 2.9 nM, 14.9 nM, and 6.4 nM for human, rat, and mouse SGLT2).Fórmula:C22H28O7Pureza:97.02% - 98.78%Forma y color:SolidPeso molecular:404.45Ref: TM-T5016
1mg46,00€2mg59,00€5mg87,00€10mg140,00€25mg259,00€50mg467,00€100mg653,00€200mg927,00€500mg1.359,00€1mL*10mM (DMSO)96,00€Canagliflozin hemihydrate
CAS:Canagliflozin hemihydrate (TA 7284) treats type 2 diabetes by blocking SGLT2, leading to glucose excretion in urine.Fórmula:C48H52F2O11S2Pureza:99.42% - 99.96%Forma y color:SolidPeso molecular:907.05SGL5213
CAS:SGL5213 is a potent oral SGLT1 inhibitor (IC50: 29 nM) with potential for treating type 2 diabetes.Fórmula:C37H55N3O8Pureza:98%Forma y color:SolidPeso molecular:669.85Phlorizin
CAS:Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) .Fórmula:C21H24O10Pureza:99.58% - 99.76%Forma y color:Solid CrystallinePeso molecular:436.41Sergliflozin A
CAS:Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia.Fórmula:C20H24O7Pureza:99.43%Forma y color:SolidPeso molecular:376.4Canagliflozin
CAS:Canagliflozin (JNJ 28431754AAA) is a selective SGLT2 inhibitor. Canagliflozin is used to treat type II diabetes mellitus. Cost-effective and quality-assured.Fórmula:C24H25FO5SPureza:100% - 99.76%Forma y color:SolidPeso molecular:444.52Mizagliflozin
CAS:Mizagliflozin is an orally active, selective SGLT1 inhibitor with a Ki value of 27 nM for human SGLT1.Cost-effective and quality-assured.Fórmula:C28H44N4O8Pureza:98.32% - 98.66%Forma y color:SolidPeso molecular:564.67Ref: TM-T16083
1mg81,00€2mg105,00€5mg163,00€10mg274,00€25mg542,00€50mg778,00€100mg1.074,00€1mL*10mM (DMSO)212,00€SGLT inhibitor-1
CAS:SGLT inhibitor-1 is a potentsodium glucose co-transporter proteins (SGLTs) dual inhibitor(hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively).Fórmula:C24H27FO8Pureza:98%Forma y color:SolidPeso molecular:462.46Trilobatin
CAS:Trilobatin (P-Phlorizin) has anti-oxidant effect, can increase superoxide dismutase (SOD) activity.Trilobatin has anti-inflammatory effect, it potentiallyFórmula:C21H24O10Pureza:97.16%Forma y color:SolidPeso molecular:436.41Ref: TM-T2S0731
1mg64,00€5mg124,00€10mg165,00€25mg323,00€50mg487,00€100mg710,00€1mL*10mM (DMSO)137,00€Sotagliflozin
CAS:Sotagliflozin (LP-802034) is an orally bioavailable inhibitor of the sodium-glucose co-transporter subtype 1 (SGLT1) and 2 (SGLT2), with potentialFórmula:C21H25ClO5SPureza:99% - 99.78%Forma y color:SolidPeso molecular:424.94Ref: TM-T3547
1mg46,00€2mg57,00€5mg87,00€10mg131,00€25mg248,00€50mg378,00€100mg560,00€500mg1.198,00€1mL*10mM (DMSO)88,00€Enavogliflozin
CAS:Enavogliflozin (DWP-16001) is an orally available small molecule and sodium glucose transporter 2 inhibitor.Fórmula:C24H27ClO6Pureza:97.81%Forma y color:SolidPeso molecular:446.92Ref: TM-T38843
1mg156,00€5mg378,00€10mg590,00€25mg1.026,00€50mg1.406,00€100mg1.863,00€1mL*10mM (DMSO)415,00€Ipragliflozin
CAS:Ipragliflozin (ASP1941) is under investigation in Type 2 Diabetes and Diabetes Mellitus, Type 2.Fórmula:C21H21FO5SPureza:99.38% - 99.70%Forma y color:SolidPeso molecular:404.45
