GTPasa
Las GTPasas son una familia de enzimas que hidrolizan el guanosín trifosfato (GTP) a guanosín difosfato (GDP), desempeñando un papel crucial en las vías de transducción de señales, incluidas las mediadas por GPCR. Las GTPasas actúan como interruptores moleculares en varios procesos celulares, como la división, el crecimiento y la diferenciación celular. La desregulación de la actividad de las GTPasas está implicada en numerosas enfermedades, incluido el cáncer y los trastornos genéticos. En CymitQuimica, ofrecemos una selección de moduladores de GTPasa de alta calidad para apoyar su investigación en señalización celular, biología del cáncer y vías relacionadas con GPCR.
Productos de "GTPasa"
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Hay 17 productos en esta categoría.
CID-4785700
CAS:CID-4785700 is a potent pan-GTPase inhibitor that inhibits Rab7 and inhibits the fungal histone acetyltransferase Rtt109 that binds to Asf1 and Vps75Fórmula:C22H23ClFN3O3Pureza:98.19%Forma y color:SolidPeso molecular:431.89Ref: TM-T71740
1mg333,00€5mg922,00€10mg1.140,00€25mg1.510,00€50mg1.882,00€100mg2.375,00€500mg4.664,00€NAV-2729
CAS:NAV-2729 inhibits six ArfGEFs (human ARNO, EFA6, BIG1, and BRAG2 and Legionella and Rickettsia RalF), the strongest effects being against BRAG2, Arf1 and Arf6.Fórmula:C25H17ClN4O3Pureza:98.83% - 98.91%Forma y color:SolidPeso molecular:456.88Ref: TM-T5142
2mg46,00€5mg66,00€10mg96,00€25mg205,00€50mg303,00€100mg454,00€500mg938,00€1mL*10mM (DMSO)74,00€CCG-63808
CAS:CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins.Fórmula:C25H15FN4O2SPureza:90%Forma y color:SolidPeso molecular:454.48RBC10
CAS:RBC10 inhibits the binding of Ral to its effector RALBP1, as well as inhibiting Ral-mediated cell spreading of murine embryonic fibroblasts and anchorage-Fórmula:C24H25ClN2O2Pureza:98.38%Forma y color:SolidPeso molecular:408.92Ref: TM-T24706
1mg34,00€2mg52,00€5mg80,00€10mg116,00€25mg259,00€50mg374,00€100mg545,00€200mg740,00€1mL*10mM (DMSO)86,00€IMM-01
CAS:IMM-01 is a novel class of small-molecule agonists of the mammalian Diaphanous (mDia)-related formins, which act downstream of Rho GTPases to assemble actinFórmula:C12H17N3O2SPureza:98.87%Forma y color:SolidPeso molecular:267.35Ref: TM-T25529
1mg52,00€5mg97,00€10mg170,00€25mg369,00€50mg593,00€100mg893,00€200mg1.198,00€1mL*10mM (DMSO)97,00€ML-097
CAS:ML-097 (CID-2160985) is a pan activator of Ras-related GTPasesFórmula:C14H11BrO3Pureza:99.12%Forma y color:SolidPeso molecular:307.139Ref: TM-T21970
5mg65,00€10mg95,00€25mg140,00€50mg202,00€100mg303,00€500mg725,00€1mL*10mM (DMSO)71,00€Compound C108
CAS:Compound C108 is an inhibitor of GTPase-activating protein SH3 domain-binding protein 2 (G3BP2).Fórmula:C15H14N2O3Pureza:99.77%Forma y color:SolidPeso molecular:270.28Ref: TM-T38387
1mg46,00€5mg89,00€10mg130,00€25mg251,00€50mg401,00€100mg597,00€500mg1.283,00€1mL*10mM (DMSO)125,00€MLS-573151
CAS:MLS-573151 is a selective inhibitor of GTPase Cdc42(EC50 of 2 μM).Fórmula:C21H19N3O2SPureza:98.80%Forma y color:SolidPeso molecular:377.46Ref: TM-T22106
2mg35,00€5mg52,00€10mg90,00€25mg170,00€50mg259,00€100mg383,00€200mg545,00€1mL*10mM (DMSO)58,00€CID-1067700
CAS:CID-1067700 is one of the first identified competitive inhibitors of nucleotide binding by Ras-related GTPases(Rab7 with a Ki of 13 nM).Fórmula:C18H18N2O4S2Pureza:99.46%Forma y color:SolidPeso molecular:390.48Ref: TM-T7558
1mg35,00€2mg52,00€5mg74,00€10mg111,00€25mg188,00€50mg246,00€100mg319,00€1mL*10mM (DMSO)82,00€CCG-63802
CAS:CCG-63802 is a reversible small-molecule inhibitor of regulator of G protein signaling (RGS) proteins.Fórmula:C26H18N4O2SPureza:90%Forma y color:SolidPeso molecular:450.51CCG-50014
CAS:CCG-50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM.Fórmula:C16H13FN2O2SPureza:98.53%Forma y color:SolidPeso molecular:316.35Anti-inflammatory agent 49
CAS:Compound SC9, an anti-inflammatory agent, serves as a potent and selective inhibitor of the Drp1-Fis1 interaction, mitigating FIS1-mediated mitochondrialFórmula:C21H22N8O3SPureza:99.62% - 99.74%Forma y color:SolidPeso molecular:466.52QS11
CAS:QS11, a GTPase ARFGAP1, modulates ARF-GTP levels and synergizes with the Wnt/β-catenin signaling pathway to upregulate β-catenin nuclear translocation.Fórmula:C36H33N5O2Pureza:98.39%Forma y color:SolidPeso molecular:567.68Ref: TM-T4022
2mg35,00€5mg52,00€10mg85,00€25mg156,00€50mg226,00€100mg340,00€200mg465,00€1mL*10mM (DMSO)65,00€Gancaonin I
CAS:Gancaonin I exhibits anti-BsFtsZ GTPase activities; it also shows significant inhibitory activity against B. subtilis, with a MIC value of 5 uM.Fórmula:C21H22O5Pureza:98%Forma y color:SolidPeso molecular:354.4BQU57
CAS:BQU57 shows selective inhibition for Ral relative to Ras or Rho and inhibit xenograft tumor growth.Fórmula:C16H13F3N4OPureza:97.45% - 98.72%Forma y color:SolidPeso molecular:334.3Exo-1
CAS:Exo-1 (Methyl 3-(4-fluorobenzoyl)-6-methyl-2-pyridinecarboxylate) is a synthetic compound that has been shown to affect the metabolism of various nutrients, asFórmula:C15H12FNO3Pureza:99.45%Forma y color:SolidPeso molecular:273.26Ref: TM-T9200
5mg55,00€10mg82,00€25mg126,00€50mg182,00€100mg273,00€200mg409,00€500mg677,00€1mL*10mM (DMSO)69,00€RBC8
CAS:RBC8 is a specific GTPases RalA/RalB inhibitor by inhibiting the binding of Ral to its effector RALBP1, no inhibition on the GTPases RhoA and Ras.Fórmula:C25H20N4O3Pureza:98.44% - 99.81%Forma y color:SolidPeso molecular:424.45Ref: TM-T6634
1mg48,00€5mg92,00€10mg156,00€25mg298,00€50mg472,00€100mg687,00€200mg938,00€1mL*10mM (DMSO)97,00€
