Receptor LPA
Los receptores de ácido lisofosfatídico (LPA) son un grupo de GPCR que responden al LPA, un lípido bioactivo involucrado en la proliferación, migración y supervivencia celular. La señalización de LPA juega un papel crucial en varios procesos fisiológicos, incluyendo la cicatrización de heridas, el desarrollo vascular y la metástasis del cáncer. La modulación de la actividad de los receptores de LPA se está explorando para aplicaciones terapéuticas en el cáncer, la fibrosis y las enfermedades inflamatorias. En CymitQuimica, ofrecemos una gama de moduladores de receptores de LPA de alta calidad para apoyar su investigación en señalización celular, oncología y trastornos inflamatorios.
Productos de "Receptor LPA"
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H2L5186303
CAS:H2L5186303 is an LPA2 antagonist and can be used in studies about asthma treatment.Fórmula:C26H20N2O8Pureza:97.23%Forma y color:SolidPeso molecular:488.45Ref: TM-T22835
1mg35,00€5mg64,00€10mg104,00€25mg226,00€50mg335,00€100mg470,00€500mg938,00€1mL*10mM (DMSO)75,00€ONO-7300243
CAS:ONO-7300243 is an antagonist of lysophosphatidic acid receptor 1 (LPA1; IC50 : 0.16 μM).Fórmula:C28H31NO5Pureza:99.66%Forma y color:SolidPeso molecular:461.55H2L 5765834
CAS:H2L 5765834 is a lysophosphatidic acid receptors antagonistFórmula:C21H12N2O7Pureza:99.47% - ≥98%Forma y color:SolidPeso molecular:404.33Ref: TM-T22834
1mg62,00€5mg119,00€10mg187,00€25mg354,00€50mg525,00€100mg747,00€1mL*10mM (DMSO)131,00€Tetradecyl Phosphonate
CAS:Tetradecyl Phosphonate 是溶血磷脂酸 1 (LPA1)、LPA2 和 LPA3 受体的泛拮抗剂。Fórmula:C14H31O3PPureza:99.95%Forma y color:White To Off-White PowderPeso molecular:278.37Radioprotectin-1
CAS:Radioprotectin-1 is a selective agonist of LPA2 with EC50 of 25 nM for murine LPA2 GPCR and exerts radioprotective and radiomitigative action.Fórmula:C23H19ClN2O6SPureza:98.75% - 99.43%Forma y color:SolidPeso molecular:486.92Ref: TM-T12684
1mg81,00€5mg170,00€10mg259,00€25mg425,00€50mg562,00€100mg775,00€1mL*10mM (DMSO)187,00€Ki16425
CAS:Ki16425 (Debio 0719) is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively.Fórmula:C23H23ClN2O5SPureza:97.60% - 97.78%Forma y color:SolidPeso molecular:474.96TAK-615
CAS:TAK-615 is commonly used to study pulmonary fibrosis and is a negative allosteric modulator of LPA1 receptors.Fórmula:C25H22FNO4Pureza:99.36%Forma y color:SolidPeso molecular:419.44Ref: TM-T9699
1mg75,00€5mg169,00€10mg259,00€25mg429,00€50mg605,00€100mg815,00€500mg1.624,00€1mL*10mM (DMSO)180,00€LPA1 receptor antagonist 1
CAS:LPA1 receptor antagonist 1(LPA1 R antagonist 1) is a lysophosphatidic acid receptor antagonist for the study of idiopathic pulmonary fibrosis.Fórmula:C28H26N4O4Pureza:99.46% - 99.58%Forma y color:SolidPeso molecular:482.53ASP6432
CAS:ASP6432 is an antagonist of type 1 lysophosphatidic acid receptor (LPA1). For human LPA1 and rat LPA1, the IC50s are 11 nM and 30 nM , respectively.Fórmula:C26H32KN4O6S2Forma y color:SolidPeso molecular:599.78Edg-2 receptor inhibitor 1
CAS:Edg-2 receptor inhibitor 1 (SAR-100842) is an Edg-2 receptor inhibitor extracted (IC50: <0.1 μM).Fórmula:C27H27NO5Pureza:99.47%Forma y color:SolidPeso molecular:445.51Ref: TM-T4521
1mg97,00€2mg170,00€5mg274,00€10mg426,00€25mg663,00€50mg947,00€100mg1.264,00€1mL*10mM (DMSO)288,00€TC LPA5 4
CAS:TC LPA5 4 is a LPA5 receptor antagonist.Fórmula:C23H23ClN2O3Pureza:99.05%Forma y color:SolidPeso molecular:410.89GRI977143
CAS:GRI977143: selective LPA2 agonist (EC50=3.3μM), blocks caspases 3/7/8/9, limits DNA fragmentation.Fórmula:C22H17NO4SPureza:98.07%Forma y color:SolidPeso molecular:391.44AM095 free acid
CAS:AM095 (free acid) is a potent LPA1 receptor antagonist (IC50s: 0.98 and 0.73 μM for recombinant human or mouse LPA1).Fórmula:C27H24N2O5Pureza:99.88%Forma y color:SolidPeso molecular:456.49Ref: TM-T10293
1mg39,00€2mg51,00€5mg84,00€10mg119,00€25mg210,00€50mg354,00€100mg550,00€200mg792,00€1mL*10mM (DMSO)92,00€DBIBB
CAS:DBIBB: non-lipid LPA2 receptor agonist, treats acute radiation syndrome, aids in organic synthesis/drug research.Fórmula:C23H20N2O6SPureza:97.18% - 97.26%Forma y color:SolidPeso molecular:452.48Ref: TM-T22070
1mg42,00€5mg93,00€10mg134,00€25mg264,00€50mg378,00€100mg553,00€500mg1.111,00€1mL*10mM (DMSO)93,00€BMS-986278
CAS:BMS-986278 is an orally active and potent hemophosphatidic acid receptor 1 (LPA1) antagonist with Kb values of 6.9 nM and 4.0 nM for human and mouse LPA1,Fórmula:C22H31N5O5Pureza:99.86%Forma y color:SolidPeso molecular:445.51Ki16198
CAS:Ki16198, a methyl ester derivative of Ki16425, blocks LPA1/3, weak on LPA2; inactive on LPA4/5/6. Ki values: 0.34 μM (LPA1), 0.93 μM (LPA3).Fórmula:C24H25ClN2O5SPureza:97.6%Forma y color:SolidPeso molecular:488.98LPA2 antagonist 1
CAS:LPA2 antagonist 1 is a potent LPA2 antagonist.Fórmula:C20H23Cl2N5O2S2Pureza:99.85%Forma y color:SolidPeso molecular:500.47UCM-05194
CAS:UCM-05194: potent LPA1 agonist, best for neuropathic pain relief (Emax 118%, EC50 0.24 μM, KD 19.6 nM, inactive at LPA2-6/autotaxin).Fórmula:C19H30BrO6PPureza:90% - 91.22%Forma y color:SolidPeso molecular:465.32AM095
CAS:AM095 is a potent LPA1 receptor antagonist with IC50 values of 0.98 and 0.73 μM for recombinant human or mouse LPA1 respectively.Fórmula:C27H23N2NaO5Pureza:99.62%Forma y color:SolidPeso molecular:478.47BMS-986020
CAS:BMS-986020 (AM152) is a selective antagonist of LPA1.Fórmula:C29H26N2O5Pureza:100% - 98.82%Forma y color:SolidPeso molecular:482.53
