Receptor de cannabinoides
Los receptores cannabinoides son GPCR que median los efectos de los cannabinoides endógenos (endocannabinoides) y los fitocannabinoides, como los encontrados en el cannabis. Los dos tipos principales de receptores cannabinoides, CB1 y CB2, están involucrados en la regulación de una amplia gama de procesos fisiológicos, incluida la percepción del dolor, el apetito, el estado de ánimo y la función inmunitaria. Los moduladores de los receptores cannabinoides tienen potencial terapéutico en el tratamiento de afecciones como el dolor crónico, la epilepsia y la esclerosis múltiple. En CymitQuimica, ofrecemos una amplia gama de moduladores de receptores cannabinoides de alta calidad para apoyar su investigación en neurofarmacología, manejo del dolor e inmunología.
Productos de "Receptor de cannabinoides"
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CB2R agonist 2
CB2R agonist 2 (cis-17-para) is a CB2R agonist [1].Pureza:98%Forma y color:Odour SolidCannabigerol
CAS:Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; alsoFórmula:C21H32O2Pureza:99.23% - 99.92%Forma y color:SolidPeso molecular:316.48Ref: TM-TN1465
1mg145,00€2mg215,00€5mg314,00€10mg474,00€25mg808,00€50mg1.111,00€100mg1.501,00€1mL*10mM (DMSO)324,00€Dehydroabiethylamine
CAS:Dehydroabiethylamine (NSC-2955) boosts liver CYP2B, blocks PDKs & cholesterol transport, and has anti-tumor effects.Fórmula:C20H31NPureza:97.24%Forma y color:Pale Yellow Viscous Liquid /Technical Grade/ Viscous Colorless To Amber LiquidPeso molecular:285.47MDA77
CAS:MDA77 is a CB2 agonist with an EC50 value of 5.82 nM and exhibits no activity towards CB1.Fórmula:C21H23N3O3Forma y color:SolidPeso molecular:365.43TRPV1/CB2 agonist 1
TRPV1/CB2 agonist 1 (compound 41) is a dual agonist targeting hTRPV1 and CB2 receptors, with an EC50 value of 26.8 μM for hTRPV1. It is applicable in research related to the nervous system.Forma y color:Odour SolidO-1602
CAS:O-1602 is a novel GPR55 agonist, an atypical cannabinoid associated with the central nervous system and obesity, and is a candidate compound for the treatmentFórmula:C17H22O2Pureza:99.4%Forma y color:SolidPeso molecular:258.36CB1 inverse agonist 1
CAS:MRL-650 is an oral, selective CB1 agonist; IC50: CB1=7.5 nM, CB2=4100 nM; anorexigenic effects noted.Fórmula:C25H18Cl3N3O3Pureza:99.12%Forma y color:SolidPeso molecular:514.79Ref: TM-T10694
1mg77,00€5mg158,00€10mg225,00€25mg338,00€50mg472,00€100mg645,00€200mg869,00€1mL*10mM (DMSO)187,00€NESS 0327
CAS:NESS 0327 is a high selectivity antagonist of the cannabinoid CB1 receptor. NESS 0327 is more than 60,000-fold selective for the CB1 receptor.Fórmula:C24H23Cl3N4OPureza:99.74%Forma y color:SolidPeso molecular:489.82CB1 agonist 1
CAS:CB1 agonist 1 is a potent CB1 agonist with a pIC50 value of 5.7 for CB1 receptors.CB1 agonist 1 can be used to study brain disorders, pain, and inflammation.Fórmula:C24H24N2O5SPureza:98.56%Forma y color:SolidPeso molecular:452.52Tetrahydromagnolol
CAS:Tetrahydromagnolol can activate cannabinoid (CB) receptors.Fórmula:C18H22O2Pureza:100% - 99.82%Forma y color:SolidPeso molecular:270.37GFB-024
GFB-024 is a humanized antibody targeting CB1, which can be used to study obesity.Forma y color:LiquidPeso molecular:145.5yangonin
CAS:Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.Fórmula:C15H14O4Pureza:98.82% - 99.55%Forma y color:Pale Yellow PowderPeso molecular:258.27Ref: TM-T3S0738
1mg70,00€5mg135,00€10mg207,00€25mg349,00€50mg515,00€100mg735,00€1mL*10mM (DMSO)177,00€Cannabidivarinic acid
CAS:Cannabidivarinic acid (CBDVA), the carboxylic acid precursor to cannabidivarin (CBDV), is a non-psychoactive cannabinoid found in Cannabis and known for its anti-inflammatory properties.Fórmula:C20H26O4Forma y color:SolidPeso molecular:330.42Amauromine
CAS:Amauromine is a peripherally selective and potent cannabinoid receptor type 1 (CB1) receptor antagonist, a novel alkaloid with vasodilatory activity.Fórmula:C32H36N4O2Forma y color:SolidPeso molecular:508.651'-Naphthoyl-2-methylindole
CAS:1'-Naphthoyl-2-methylindole (Compound 88) acts as a cannabinoid mimic and an inhibitor of Win 55212-2, displaying a 34% inhibition of [3H]Win 55212-2 binding to cannabinoid receptors at a concentration of 3 μM.Fórmula:C20H15NOForma y color:SolidPeso molecular:285.34CB1/2 receptor-1
CAS:CB1/2 receptor-1 (compound 5.3) serves as an agonist for CB1/2 receptors and is utilized in angiogenesis research.Fórmula:C33H48O2Forma y color:SolidPeso molecular:476.73Bzo-poxizid
CAS:Bzo-poxizid is a synthetic cannabinoid and a psychoactive substance.Fórmula:C20H21N3O2Forma y color:SolidPeso molecular:335.40(±)-9-Nor-9α-hydroxy Hexahydrocannabinol
CAS:(±)-9-Nor-9α-hydroxy Hexahydrocannabinol is a cannabinoid-structured compound that exhibits potent cannabinoid-like activity in both dogs and mice.Fórmula:C20H30O3Forma y color:SolidPeso molecular:318.45Virodhamine
CAS:Virodhamine (O-arachidonoyl ethanolamine), an endocannabinoid, is an antagonist of CB1 receptor and an agonist of CB2 receptor.Fórmula:C22H37NO2Pureza:98%Forma y color:SoildPeso molecular:347.53Voacamine
CAS:Voacamine: an indole alkaloid, CB1 antagonist, inhibits P-gp, may affect rhythm.Fórmula:C43H52N4O5Pureza:98.54%Forma y color:SolidPeso molecular:704.9Palmitoyl serinol
CAS:Anticancer agent 110 is an anticancer compound with cytotoxic, antitumor and antileukemic activities.Fórmula:C19H39NO3Forma y color:SolidPeso molecular:329.52CB-25
CAS:CB-25 is a partial agonist ligand of CB1 cannabinoid receptors, augmenting Forskolin-induced cAMP formation in cancer cells, though not affecting hCB1-CHO cellsFórmula:C25H41NO3Pureza:98%Forma y color:SolidPeso molecular:403.6GW842166X
CAS:GW842166X: Potent CB2 agonist, EC50=63 nM, inactive at CB1, in Phase 2 trials.Fórmula:C18H17Cl2F3N4O2Pureza:99.47%Forma y color:SolidPeso molecular:449.25Ref: TM-T6527
1mg35,00€2mg50,00€5mg77,00€10mg123,00€25mg224,00€50mg330,00€100mg492,00€1mL*10mM (DMSO)74,00€Org 27569
CAS:Org 27569, an allosteric modulator of cannabinoid CB1 receptor, can induce a CB1 receptor state that is characterized by decreased inverse agonist affinity andFórmula:C24H28ClN3OPureza:100% - ≥95%Forma y color:SolidPeso molecular:409.95N-Oleoyl glycine
CAS:N-Oleoyl glycine, a lipoamino acid, was able to promote 3T3-L1 adipogenesis through the activation of CB1 receptor and the enhancement of insulin-mediated AktFórmula:C20H37NO3Pureza:99.92%Forma y color:SolidPeso molecular:339.512,3-Butanediol
CAS:2,3-Butanediol is a butanediol derived from the bioconversion of natural resources which has great potential for diverse industries, including chemical,Fórmula:C4H10O2Pureza:98.64%Forma y color:Nearly Colorless Crystalline Solid Or Liquid SolidPeso molecular:90.12O-1269
CAS:O-1269 acts as a partial agonist for the cannabinoid receptor 1 (CB1R), with a binding affinity (Ki) of 32 nM. Additionally, it exhibits analgesic properties.Fórmula:C22H22Cl3N3OForma y color:SolidPeso molecular:450.79AB-FUBINACA 3-fluorobenzyl isomer
CAS:AB-FUBINACA 3-fluorobenzyl isomer is a synthetic cannabinoid and an indazole derivative, exhibiting high affinity for central CB1 receptors (Ki= 0.9 nM) and possessing anticonvulsant activity.Fórmula:C20H21FN4O2Forma y color:SolidPeso molecular:368.41AM-1235
CAS:AM-1235 is a potent and selective cannabinoid receptor CB1 agonist.Fórmula:C24H21FN2O3Pureza:99%Forma y color:SolidPeso molecular:404.43CB 65
CAS:CB 65 is a high affinity and selective CB2 receptor agonist with Ki values of 3.3 and > 1000 nM for CB2 and CB1 receptors respectively.Fórmula:C22H28ClN3O3Pureza:98.39%Forma y color:SolidPeso molecular:417.93LY2828360
CAS:LY2828360: CB2 agonist, Ki=40.3 nM; biases CB2 over CB1 with EC50s of 20.1 nM and >100 μM.Fórmula:C22H27ClN6OPureza:98.45% - 99.51%Forma y color:SolidPeso molecular:426.94FDU-PB-22
CAS:FDU-PB-22, a novel synthetic cannabinoid, undergoes rapid metabolism in human liver microsomes (HLM) with a half-life of 12.4 minutes.Fórmula:C26H18FNO2Forma y color:SolidPeso molecular:395.43CB1 antagonist 1
CAS:CB1 antagonist 1 is a CB1 receptor antagonist, used in the research of obesity and metabolic syndrome, neuroinflammatory disorders, cognitive disorders, andFórmula:C26H22Cl2N4Pureza:98%Forma y color:SolidPeso molecular:461.39APP-FUBINACA
CAS:APP-FUBINACA is a cannabinoid receptor agonist, classified as a phenylalanine amide-based indazole-3-carboxamide derivative. It exhibits neurostimulatory effects.Fórmula:C24H21FN4O2Forma y color:SolidPeso molecular:416.45MJ 15
CAS:MJ 15 is a CB1 receptor antagonist with specificity for the study of obesity-induced diseases.Fórmula:C23H17Cl3N4OPureza:99.63%Forma y color:SolidPeso molecular:471.77Afubiata
CAS:ADB-FUBIATA is a synthetic cannabinoid studied for its metabolic profile, along with AFUBIATA, CH-FUBIATA, and CH-PIATA. This in vitro analysis by Watanabe S, et al., examines these compounds, as published in "Arch Toxicol," 2023 Dec;97(12):3085-3094.Fórmula:C27H29FN2OForma y color:SolidPeso molecular:416.53AM281
CAS:AM 281, a cannabinoid antagonist, reduces neurologic dysfunction and mortality rate after cecal ligation and puncture in rats.Fórmula:C21H19Cl2IN4O2Pureza:100% - 99.2%Forma y color:White To Off-White SolidPeso molecular:557.21Ref: TM-T2264
1mg85,00€5mg172,00€10mg274,00€25mg552,00€50mg792,00€100mg1.093,00€500mg2.175,00€1mL*10mM (DMSO)245,00€PSB-SB-487
CAS:PSB-SB-487 is antagonist of GPR55.Fórmula:C26H32O4Pureza:98.53%Forma y color:SolidPeso molecular:408.53Ref: TM-T8975
1mg38,00€5mg85,00€10mg126,00€25mg245,00€50mg364,00€100mg507,00€200mg697,00€1mL*10mM (DMSO)93,00€MDA7
CAS:MDA7 is a selective agonist of the cannabinoid receptor 2 (CB2), demonstrating an EC50 of 128 nM in human CB2 receptors and 67.4 nM in rat CB2 receptors. The compound exhibits good affinity for CB2 receptors, with Ki values of 422 nM for humans and 238 nM for rats. In rat models, MDA7 shows analgesic activity.Fórmula:C22H25NO2Forma y color:SolidPeso molecular:335.439Drinabant
CAS:Drinabant (AVE-1625) is an orally active CB1 receptor antagonist.Fórmula:C23H20Cl2F2N2O2SPureza:99.8%Forma y color:SolidPeso molecular:497.38Ref: TM-T21861
1mg87,00€2mg116,00€5mg170,00€10mg259,00€25mg425,00€50mg598,00€100mg810,00€500mg1.624,00€AM6545
CAS:AM6545 is a CB1 receptor antagonist used in the study of obesity and diabetes.Fórmula:C26H23Cl2N5O3SPureza:97.03%Forma y color:SolidPeso molecular:556.46PSNCBAM-1
CAS:PSNCBAM-1 (PSNCBAM 1) is a CB1 receptor negative allosteric modulator (EC50 = 0.1 μM) with hypophagic effects in vivo.Fórmula:C22H21ClN4OPureza:98.18%Forma y color:SolidPeso molecular:392.88L-α-lysophosphatidylinositol sodium
CAS:L-α-lysophosphatidylinositol sodium is an endogenous ligand of GPR55 and an endocannabinoid neurotransmitter.Fórmula:C25H48NaO12PForma y color:SolidPeso molecular:594.6Falcarinol
CAS:Falcarinol, also known as Panaxynol, is a naturally occurring compound that acts as an orally active inhibitor of Hsp90.Fórmula:C17H24OPureza:98%Forma y color:SolidPeso molecular:244.37AM1241
CAS:AM-1241 is a selective cannabinoid CB2 receptor agonist with Ki of 3.4 nM, exhibits 82-fold selectivity over CB1 receptor.Fórmula:C22H22IN3O3Pureza:98.82% - 99.10%Forma y color:SolidPeso molecular:503.33Ref: TM-T6755
2mg38,00€5mg51,00€10mg88,00€25mg172,00€50mg290,00€100mg523,00€500mg1.130,00€1mL*10mM (DMSO)93,00€GW 405833
CAS:GW 405833 (L-768242) is an agonist of cannabinoid-2 (CB(2)) receptor-selectiveFórmula:C23H24Cl2N2O3Pureza:99.82% - 99.93%Forma y color:SolidPeso molecular:447.35Linoleoyl Ethanolamide
CAS:Linoleoyl Ethanolamide is an endocannabinoid agent.Fórmula:C20H37NO2Pureza:99.97%Forma y color:SolidPeso molecular:323.51Ref: TM-T8425
1mg35,00€5mg67,00€10mg90,00€25mg164,00€50mg239,00€100mg348,00€200mg522,00€1mL*10mM (DMSO)85,00€Anandamide
CAS:Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide), an immune modulator, acts via not only cannabinoid receptors (CB1 and CB2) but alsoFórmula:C22H37NO2Pureza:98.76% - 99.22%Forma y color:Light Yellow OilPeso molecular:347.53Ref: TM-T14046
1mg35,00€2mg49,00€5mg74,00€10mg131,00€25mg246,00€50mg366,00€100mg538,00€200mg752,00€1mL*10mM (DMSO)81,00€exo-Tetrahydrocannabivarin
CAS:exo-Tetrahydrocannabivarin (Compound 12) is an analog of Δ9,11-THC. It weakly binds to cannabinoid receptors (CB) with an IC50 of 1.4 μM. In mice, exo-Tetrahydrocannabivarin exhibits activity related to both motor function and analgesia.Fórmula:C19H26O2Forma y color:SolidPeso molecular:286.41Arvanil
CAS:Arvanil (N-Vanillylarachidonamide) is a synthetic capsaicin-amphetamine hybrid that acts as a ligand for VR1 and CB1, offering neuroprotective effects.Fórmula:C28H41NO3Pureza:99.49%Forma y color:SolidPeso molecular:439.63
