Síntesis de ADN / ARN
Los inhibidores de la síntesis de ADN y ARN son compuestos que interfieren con los procesos de replicación y transcripción en las células, impidiendo así la producción de material genético esencial. Estos inhibidores pueden dirigirse a diversas enzimas y proteínas involucradas en la síntesis de ácidos nucleicos, lo que los convierte en herramientas valiosas para estudiar los mecanismos de replicación, transcripción y traducción. También se utilizan en el desarrollo de tratamientos para infecciones y cáncer. En CymitQuimica, ofrecemos un amplio espectro de inhibidores de la síntesis de ADN/ARN para apoyar su investigación en biología molecular, virología y desarrollo terapéutico.
Productos de "Síntesis de ADN / ARN"
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TH588
CAS:TH588 is nudix hydrolase family inhibitor that effectively and selectively engages and inhibits the MTH1(IC50: 5 nM) in cells.Fórmula:C13H12Cl2N4Pureza:96.05% - 99.82%Forma y color:SolidPeso molecular:295.17Werner syndrome RecQ helicase-IN-1
CAS:Werner syndrome RecQ helicase-IN-1 is a potent Werne r syndrome RecQ DNA deconjugase (WRN) inhibitor that can be used to study cancers such as colon and stomachFórmula:C31H31ClF3N9O5Pureza:98.74% - 99.62%Forma y color:SolidPeso molecular:702.08Ref: TM-T72107
1mg60,00€5mg125,00€10mg177,00€25mg296,00€50mg502,00€100mg803,00€500mg1.795,00€1mL*10mM (DMSO)822,00€NITD-2
CAS:NITD-2 is a DENV RdRp inhibitor with poor cell membrane penetration; no vaccine or antiviral for DENV exists.Fórmula:C23H19N3O4SPureza:98.03% - 99.46%Forma y color:SolidPeso molecular:433.48Ref: TM-T8886
1mg74,00€5mg170,00€10mg274,00€25mg472,00€50mg655,00€100mg944,00€200mg1.264,00€1mL*10mM (DMSO)188,00€RG7800
CAS:RG7800 (RO6885247) has the potential for spinal muscular atrophy treatment. RG7800 is an SMN2 splicing modifier.Fórmula:C24H28N6OPureza:99.44%Forma y color:SolidPeso molecular:416.52ART558
CAS:ART558 is a potent, selective, low molecular weight, allosteric DNA polymerase activity of Polθ inhibitor (IC50=7.9 nM).Fórmula:C21H21F3N4O2Pureza:99.18%Forma y color:SolidPeso molecular:418.41T4 RNA ligase
T4 RNA ligase is an enzyme that facilitates the ligation of single-stranded DNA.Pureza:98%Forma y color:Odour SolidAT-130
CAS:AT-130: Strong HBV inhibitor (IC50 0.13 μM), low toxicity in HepAD38, hinders RNA packaging.Fórmula:C22H22BrN3O5Pureza:97.81%Forma y color:SolidPeso molecular:488.33Ref: TM-T26674
1mg42,00€5mg90,00€10mg131,00€25mg226,00€50mg339,00€100mg509,00€200mg698,00€1mL*10mM (DMSO)87,00€Methotrexate
CAS:Methotrexate (WR19039) is a folate analog, an inhibitor of the dihydrofolate reductase DHFR.Fórmula:C20H22N8O5Pureza:96.84% - 99.46%Forma y color:Orange-Brown Crystalline Powder Chemotherapy Drug That Interferes With Dna And Rna SynthesisPeso molecular:454.44DDD85646
CAS:DDD85646 is an inhibitor of T. brucei N-myristoyltransferase with a Ki of 1.44 nM, an IC50 of 2 nM and an EC50 of 2 nM. The IC50 of hNMT is 4 nM.Fórmula:C21H24Cl2N6O2SPureza:97.8% - 99.76%Forma y color:SolidPeso molecular:495.43Ref: TM-T27135
1mg96,00€5mg279,00€10mg420,00€25mg682,00€50mg947,00€100mg1.301,00€200mg1.738,00€1mL*10mM (DMSO)305,00€Quinizarin
CAS:Quinizarin (1,4-Dihydroxyanthraquinone) is a natural productFórmula:C14H8O4Pureza:97.02%Forma y color:Leaves Yellow Red And Needles Dark Red Solid Leaves Or NeedlesPeso molecular:240.21Enrofloxacin
CAS:Enrofloxacin (BAY-Vp2674) is a veterinary antibacterial agent, used in poultry.Fórmula:C19H22FN3O3Pureza:100% - 99.89%Forma y color:Pale Yellow CrystalsPeso molecular:359.39TK216
CAS:TK216 is a potent inhibitor of E26 transformation-specific (ETS) with anticancer activity.Fórmula:C19H15Cl2NO3Pureza:97.22%Forma y color:SolidPeso molecular:376.23DTP3
CAS:DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.Fórmula:C26H35N7O5Forma y color:SolidPeso molecular:525.6BMH-21
CAS:BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.Fórmula:C21H20N4O2Pureza:98.87% - 99.53%Forma y color:SolidPeso molecular:360.41SCR7
CAS:SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).Fórmula:C18H14N4OSPureza:98%Forma y color:SolidPeso molecular:334.4GS-9191
CAS:GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , whichFórmula:C37H51N8O6PPureza:98.01% - 98.28%Forma y color:SolidPeso molecular:734.82NRTT-IN-1
CAS:NRTT-IN-1 (Compound 1) is an inhibitor of the nucleoside reverse transcriptase translocation (NRTT), effectively blocking HIV DNA synthesis and viral replication.Fórmula:C28H24FN5O5Forma y color:SolidPeso molecular:529.519Taq DNA polymerase
CAS:Taq DNA polymerase is a thermostable enzyme utilized in polymerase chain reactions (PCR) to amplify DNA sequences [1].Pureza:98%Forma y color:SolidO6-Benzylguanine
CAS:O6-Benzylguanine is a guanine analog with antineoplastic activity,and is a potent O6-alkylguanine DNA alkyltransferase (AGT) inactivator.Fórmula:C12H11N5OPureza:98.90%Forma y color:Solid CrystallinePeso molecular:241.25DHX9-IN-2
CAS:DHX9-IN-2 is an inhibitor targeting ATP-dependent RNA de-helicase A (DHX9) with anticancer and antitumor activity for cancer research.Fórmula:C18H16ClN3O3S2Pureza:98.00%Forma y color:SolidPeso molecular:421.92
