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Honokiol analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Please enquire for more information about 6-Benzyloxy-5-methoxyindole including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Byakangelicol may reduce P-gp at BBB and has anti-inflammatory effects by hindering COX-2 and PGE2 in A549 cells.

Please enquire for more information about Methyl 3-{[(1E)-(dimethylamino)methylene]amino}-5-methyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Propyl 2-(4-methylphenyl)-1,3-dioxoisoindoline-5-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Methylpyrazolo[1,5-a]pyrimidine-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

The impurity 1-[2-[(3S)-3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-hydroxypropyl]phenyl]acetate is an organic compound. It is a metabolite of the drug montelukast sodium, which is used for the treatment of asthma and other allergic disorders. The compound has been found in rats to have toxicological effects on the liver and kidneys. Impurities can be identified by their retention time on a chromatographic column. This impurity was detected using an ethanone extraction followed by a thin layer chromatography analysis with a solvent mixture of methanol and acetic acid (9:1).

Please enquire for more information about 2,3-Dihydro-1H-indole-4-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 8-Chloro-2-hydroxyquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Trans-3-indoleacrylic acid (TIAA) is a metabolite that is produced by the degradation of tryptophan. TIAA has been shown to have a matrix effect on cells, which influences their energy production and regulation. TIAA has also been shown to be involved in the synthesis of proteins, such as the signal peptide and polymerase chain reaction (PCR). TIAA may also be involved in transcription activators and metabolic disorders. The effects of TIAA are most likely due to its ability to inhibit synthetase activity.

Please enquire for more information about 3-Bromo-5-nitro-1-trityl-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Methyl-2-pyridin-3-ylquinoline-4-carbonyl chloride hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(3-Aminophenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Quinolin-5-yl-methylamine is a fine chemical that is used as a research chemical. It can be used as a reagent and as a speciality chemical. This compound has a high quality and is versatile in its use. Quinolin-5-yl-methylamine can be used in the synthesis of complex compounds, such as pharmaceuticals, agrochemicals, and polymers. It is also an intermediate that can be used to create other useful compounds, such as building blocks or scaffolds. The CAS number for this compound is 58123-57-2.

2-ChloromethylQuinoline is a phosphorus pentachloride compound that can be used in the synthesis of many different heterocyclic compounds. It has been shown to inhibit the DPP-IV enzyme, which prevents the breakdown of proteins. 2-ChloromethylQuinoline has also been shown to be a strong antimicrobial agent against bacteria and fungi, as well as a potent inhibitor of protein synthesis in cells. 2-ChloromethylQuinoline binds to proteins through its carbonyl group and nitro groups, inhibiting their function. It has been shown to have congestive heart failure effects in animals, and may cause light emission under certain conditions.

Please enquire for more information about Isoquinolin-7-ylboronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

1,1'-Bicyclo[1,1,1]pentane-1,3-dicarboxylic acid dimethyl ester is a fluorinated analog of the diacid 1,2-cyclohexanedicarboxylic acid. It has been studied by computational and experimental methods to elucidate its properties. 1,1'-Bicyclo[1,1,1]pentane-1,3-dicarboxylic acid dimethyl ester has been shown to undergo bond cleavage at the C-C and C-F bonds with a half life of approximately one day under simulated physiological conditions. The single crystal X-ray diffraction study showed that 1,2-bicyclo[1,1,1]pentane-1,3-dicarboxylic acid dimethyl ester has a planarity of 0.539(6) Å for the central carbon atom.

Please enquire for more information about 5,7-Dichloroquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

1,2-Dihydrobenzene (1,2-DH) is a molecule that has the chemical formula C6H6. It is a colorless liquid with boiling point of 147°C and melting point of -11°C. 1,2-DH has been shown to form hydrogen bonds with water molecules. This compound is also insoluble in water, which may be due to its dehydrating properties. When catalyzed by an acid or base, 1,2-DH undergoes dehydration reactions. Acidic or basic conditions are required for this reaction to occur and the resulting product can be determined by x-ray diffraction studies. 1,2-DH has been shown to form coordination complexes with metal ions such as copper (Cu) and zinc (Zn). These complexes have been shown to have ligand binding properties that lead to supramolecular structures. Intermolecular hydrogen bonding interactions between 1,2-DH molecules have also been observed during

Please enquire for more information about 7-Bromo-3-nitroquinolin-4-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page

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4-Quinolinecarboxaldehyde is a quinoline derivative that is an electrophilic reagent. It reacts with nucleophiles in the presence of base to produce quinolines. 4-Quinolinecarboxaldehyde can be used as a chemical intermediate for preparing various drugs, such as epidermal growth factor and phosphite. The Langmuir adsorption isotherm has been used to study the binding of this compound to bacterial cells. This molecule also has electrochemical impedance spectroscopy and x-ray diffraction data available. 4-Quinolinecarboxaldehyde is stable in low energy environments and can be stored at room temperature without decomposing.

8-Geranyloxypsoralen is a natural furanocoumarin, which is a secondary metabolite typically derived from plants, particularly those in the Rutaceae family. Its source lies predominantly in certain fruits and herbs, where it functions as a natural defense compound. The mode of action of 8-Geranyloxypsoralen involves its interaction with DNA upon activation by ultraviolet (UV) light. It can form covalent bonds with pyrimidine bases, primarily thymine, in the DNA strands. This interaction leads to the formation of monoadducts, which can subsequently result in crosslinking upon further exposure to UV-A, disrupting DNA replication and transcription processes. 8-Geranyloxypsoralen finds its applications in phototherapy and is often studied for its potential therapeutic uses in skin diseases, such as psoriasis, and vitiligo. Its ability to modulate biological responses under light exposure makes it a candidate for further exploration in understanding light-mediated cellular processes. Furthermore, it provides insights into plant defense mechanisms and the complex interactions between plant-derived compounds and biological systems under environmental stressors.

Applications Bicyclo[4.1.0]Heptane-7-Carboxylic Acid (cas# 41894-76-2) is a useful reagent for the heteroatom-​directed C-​H borylation of cyclopropanes and cyclobutanes. References Murakami, R., et al.: Chem. Eur. J., 20, 13127 (2014)

7-Azaindole-5-carboxylic acid methyl ester is an ester derivative that can be synthesized from the reaction of acetyl chloride and diazotization. 7-Azaindole-5-carboxylic acid methyl ester has been used in research for its biological activity, specifically as a cytotoxic agent. It has also been shown to inhibit the growth of cancer cells by alkylation reactions and cyclization reactions. 7-Azaindole-5-carboxylic acid methyl ester has been shown to have antitumor properties with a mechanism that is not yet fully understood.

Applications methyl 8,8-dioxo-8lambda6-thia-2,3,5,7-tetraazatricyclo[7.4.0.0,2,6]trideca-1(13),3,5,9,11-pentaene-4-carboxylate (cas# 1311315-62-4) is a useful research chemical.

3-Iodoquinolin-4-ol is a synthetic compound that inhibits bacterial growth by inhibiting the synthesis of RNA and DNA. It has been shown to be active against Gram-positive bacteria, including Staphylococcus aureus and Enterococcus faecalis, but not against Gram-negative bacteria such as Escherichia coli. 3-Iodoquinolin-4-ol also has potentiating effects on the CFTR protein in cells with the F508del mutation. This mutation affects the chloride channel present in the cell membrane, which leads to an increased amount of salt in body fluids and can cause cystic fibrosis (CF). The terminal alkynes within this molecule are bioisosteres for amides when they are coupled to boronic acids, which were used in an assay to measure bacterial activity.

Please enquire for more information about 1-(2-Chloro-4-Fluorobenzyl)-1H-Indole-3-Carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 5-Fluoroindole is a reactant used in various syntheses. It was used in the synthesis of Spirotetrahydro β-Carbolines (Spiroindolones), which is a new class of potent and orally efficacious compounds for the treatment of malaria. 5-Fluoroindole was also a reactant in direct indole and pyrrole couplings to carbonyl compound in total synthesis of Acremoauxin A and Oxazinin 3. References Richter, J., et al.: J. Am. Chem. Soc., 129, 12857 (2007); Yeung, B., et al.: J. Med. Chem., 53, 5155 (2010);

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5-Methyl-2-phenyl-1H-imidazole-4-carboxylic acid (MPICA) is a potent inhibitor of xanthine oxidase. It is also an inhibitor of β-glucuronidase and enzymes that maintain the integrity of bacterial DNA. MPICA has been shown to inhibit xanthine oxidase in a dose dependent manner and can be used as a lead compound for new inhibitors of this enzyme.

4-Methoxy-2,3-dihydro-1H-indole is a synthetic compound that can be prepared by bromination of 4-methoxyindole. This reaction is regioselective and the desired isomer can be obtained in good yield. Concurrent nitration and bromination reactions are investigated with the aim of obtaining an efficient method for the synthesis of 2,3-dihydrobenzo[b]indoles. The photolabile nature of the bromide group on 4-methoxy-2,3-dihydro-1H-indole makes it possible to selectively debrominate this functional group under mild conditions.

Please enquire for more information about 1-Methyl-indazole-5-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Bromo-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(3-Butoxyphenyl)-6,8-dimethylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Bromo-5-methyl-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Methyl-N-phenyl-1,2,3,4-tetrahydroquinolin-4-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Chloro-7,8-dimethoxy-5H-pyrimido[5,4-b]indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(4-Bromophenyl)-8-methylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(4-Propylphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Coumarin 6 (Coumarin VI) is a fluorescent dye frequently used to facilitate the traceability of drug delivery systems in vitro.

Please enquire for more information about N'-[(1-Butyl-1,2,3,4-tetrahydroquinolin-6-yl)methyl]-N,N-diethylpropane-1,3-diamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Pyrazolo[1,5-a]pyrimidine is a pyrimidine compound that inhibits the synthesis of gamma-aminobutyric acid (GABA) in the central nervous system. It has been shown to have antimicrobial properties, as well as antihypertensive activity. Pyrazolo[1,5-a]pyrimidine also has an anti-inflammatory effect and can be used to treat infectious diseases, autoimmune diseases, and syncytial virus infections. This drug also has pharmacokinetic properties that are characterized by a short half-life in humans and rapid excretion of unchanged pyrazolo[1,5-a]pyrimidine in urine. Pyrazolo[1,5-a]pyrimidine binds to the mitochondrial membrane potential by inhibiting fatty acid synthesis and reduces the production of reactive oxygen species (ROS).

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8-[4-(4-Fluorophenyl)-4-Oxobutyl]-3-Methyl-3,8-Diazaspiro[4.5]Decane-2,4-Dione is a chemical substance that has been shown to have an effect on lung function in mice. It was tested on CD-1 mice and found to increase the pulmonary resistance (R) of the lungs in response to methacholine challenge. 8-[4-(4-Fluorophenyl)-4-Oxobutyl]-3-Methyl-3,8-Diazaspiro[4.5]Decane-2,4-Dione also reduces the degree of lung inflammation and improves the respiratory function in mice with inflammatory airway disease. This compound has been shown to inhibit bacterial growth in vitro by inhibiting protein synthesis through inhibition of ribosomal activity.

2-Chloro-4-methylquinoline-3-carbonitrile is an organic compound that can be synthesized in a scalable way. It has the chemical formula C8H6ClN and can be prepared by reacting dimethylamine with chlorine and bromides. 2-Chloro-4-methylquinoline-3-carbonitrile is a nucleophilic heteroaromatic compound that is able to react with halide ions through its electrophilic carbon atom. This reaction can lead to the formation of a new heterocycle, which may have many applications in organic chemistry.

Lithiumtetra(2-methyl-8-hydroxyquinolinato)boron is a photophysical, magnetic resonance spectroscopy, elemental, crystallography, and x-ray crystallography compound. It has a transition metal core with four boron ligands. The compounds are useful for studying the interactions of organic molecules with transition metals.

Please enquire for more information about 2-(4-Bromophenyl)-6,8-dimethylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications Methyl Oxindole-6-carboxylate is an intermediate used to prepare BIBF 1120, an indolinone as triple angiokinase inhibitors. References Roth, G., et al.: J. Med. Chem., 52, 4466 (2009)

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5-Oxo-5-[[(2S)-1-oxo-1-[[2-oxo-4-(trifluoromethyl)-1H-quinolin-7-yl]amino]-3phenylpropan-2-yl]amino]pentanoic acid (AFPC) is a fluorescent substrate used to measure the kinetics of chymotrypsin. The fluorescence intensity increases with the increase in the concentration of AFPC, indicating that the reaction is occurring at an increasing rate. AFPC is a fluorogenic substrate for chymotrypsin and can be used as a marker for enzyme activity. It displays high sensitivity and fast kinetics, which makes it suitable for use in kinetic assays.

Please enquire for more information about 2-(9,9-Dimethyl-9-h-floren-2-yl)quinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Gatifloxacin is a fluoroquinolone antibiotic that inhibits the DNA gyrase and topoisomerase IV, which are enzymes that maintain the integrity of bacterial DNA. It binds to bacterial 16S ribosomal RNA and inhibits protein synthesis, leading to cell death by inhibiting the production of proteins vital for cell division. Gatifloxacin has been shown to be effective against methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium perfringens, although is not active against acid-fast bacteria such as Mycobacterium tuberculosis or Mycobacterium avium complex. Gatifloxacin has shown anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

3-Methyl-2-chloro-3H-imidazo[4,5-f]quinoline is a synthetic organic compound that has been used as a research tool. The compound features an imidazole ring with a methyl and chloro substituent at the 3 and 2 positions respectively. It is soluble in alcohols and organic solvents such as acetonitrile. 3-Methyl-2-chloro-3H-imidazo[4,5-f]quinoline has been shown to induce cancer in laboratory animals and may be carcinogenic for humans. The mechanism of its carcinogenicity may be due to its ability to bind with DNA and form adducts, which inhibit DNA replication or repair.

Please enquire for more information about 2-(4-Ethylphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

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