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Please enquire for more information about 1-(3-Chlorophenyl)octahydroisoquinolin-4a(2H)-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Lactone

Please enquire for more information about 2-(5-Chlorothien-2-yl)-6-ethylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-(1H)-Indazole carboxylic acid methyl ester is an enzyme inhibitor that binds to the active site of α-amylase, which is an enzyme that hydrolyzes starch into maltose. 4-(1H)-Indazole carboxylic acid methyl ester has been shown to inhibit the activity of α-amylase by binding to the enzyme's active site and preventing it from catalyzing reactions.

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Please enquire for more information about 2-Octahydroisoquinolin-2(1H)-ylethanamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 9-(Trimethylsilyl)-2,6-bis[(trimethylsilyl)oxy]-9H-purine is an intermediate used in the synthesis of Xanthosine-13C5 (X742102), which is the labeled analogue of Xanthosine (X742100), the deamination product of Guanosine. It is also a potential biomarker for detecting radiation exposure. References Magasanik, B, et al.: J. Bio. Chem., 206, 83 (1954);

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6-Fluoro (1H)indazole is a prodrug that is metabolized in vivo to the active form, 6-fluoro (1H)indazol. 6-Fluoro (1H)indazole has dose-dependent activity and can be used as an oral therapy for mineralocorticoid receptor activation. The drug binds to the active site of the ns5b polymerase and inhibits viral replication. It has been shown to be effective against HIV-1, HCV, influenza A virus, and herpes simplex virus type 2. 6-Fluoro (1H)indazole is an analog of fludrocortisone that can be used in place of this hormone in patients with adrenal insufficiency due to its ability to bind to the mineralocorticoid receptor.

6-Nitroquinoline is a nucleophilic compound that reacts with nitroalkanes to form alkyl nitrites. It undergoes a bioreductive reaction, in which it is reduced to the corresponding amine by hydrogen peroxide and ammonia. 6-Nitroquinoline contains functional groups that can act as either electron donors or electron acceptors and is therefore reactive towards other compounds. The reaction mechanism involves nucleophilic attack at the carbon atom in the ring of the 6-nitroquinoline molecule, resulting in an addition product. 6-Nitroquinoline has been shown to react with fluorophores such as fluorescein, forming a fluorescent product that can be detected by spectroscopy. This chemical can also form hydrogen bonds with other molecules, which are important for its reactivity. The reaction products of this compound are nitrite and quinolines where one or more of the nitrogens have been oxidized to nitro groups. END

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Please enquire for more information about (1R,3R)-Methyl-1,2,3,4-tetrahydro-1-(3,4-methylenedioxyphenyl)-9H-pyrido[3,4-b]indole-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Please enquire for more information about 1H-Indole-2-propanoic acid,3-[(1,1-dimethylethyl)thio]-5-methoxy-methylester including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Methyl-1H-indole-2-carboxyaldehyde (3MICA) is a reactive compound that can be used as an intermediate for the synthesis of other compounds. 3MICA has the potential to form two products: the imine and anion. The reaction product depends on the pH, temperature, and concentration of 3MICA. Kinetic studies have shown that at higher concentrations and lower pH, the formation of imine is favored over anion. When imine is formed, it can react with hydrogen peroxide to form a peroxide (ROOH). When anion is formed, it can react with another molecule of 3MICA to form a methylene. The detection limit for 3MICA is 0.5 ppm.br>br> 3-Methyl-1H-indole-2-carboxyaldehyde has been found in three natural sources: chili peppers, citrus peels and grapefruit peels.

Impurity Famciclovir USP Related Compound F Applications Famciclovir USP Related Compound F

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Please enquire for more information about 3-{[(3,4-Dichlorophenyl)amino]carbonyl}bicyclo[2.2.1]hept-5-ene-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

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Phellopterin is a bioactive compound belonging to the class of furanocoumarins. It is extracted from various plants within the Apiaceae family, notably Angelica and Peucedanum species. These plants are found in diverse geographical regions and have been used in traditional medicine for centuries. The mechanism of action of phellopterin involves its ability to interact with multiple biological pathways. It is known to exhibit inhibitory effects on enzymes and has potential antioxidant properties. Additionally, phellopterin has demonstrated modulation of cellular signaling pathways, which may contribute to its therapeutic potential. Phellopterin is primarily investigated for its applications in pharmacology and medicine. Research suggests that it may have beneficial effects in treating inflammatory conditions, enhancing immune response, and exerting antitumor activities. It is also studied for its neuroprotective effects and potential role in managing neurodegenerative diseases. The compound’s ability to interact with various biomolecular targets makes it a subject of interest in the development of new therapeutic agents. As research progresses, the full spectrum of phellopterin's pharmacological effects continues to be unveiled, leading to its consideration in novel drug development and therapeutic strategies.

Indole-3-carboxaldehyde is a chemical compound that is used as an antimicrobial agent. The biological properties of this compound are not well studied, but it has been shown to be effective against bacteria and fungi. Indole-3-carboxaldehyde has been shown to inhibit the enzyme activity of sodium carbonate, which is involved in the production of lactic acid in bacteria. This effect may contribute to its antibacterial activity. Indole-3-carboxaldehyde is also a potential anticancer agent because it can bind to toll-like receptor 4 (TLR4). Indole-3-carboxaldehyde reacts with sulfa drugs through a mechanism similar to the reaction between hydrogen peroxide and potassium permanganate. It has been shown that indole-3-carboxaldehyde can be used as a pesticide for plants and as an electrochemical impedance spectroscopy probe for histological analysis.

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2-Phenyl-4-quinolinecarboxylic acid is a nonsteroidal anti-inflammatory drug that is commonly used to treat bronchoconstrictor response and inflammatory bowel disease. It is also an antimicrobial agent, which can be used to treat infectious diseases. The compound was found to have structural similarity to other nonsteroidal anti-inflammatory drugs, such as ibuprofen and naproxen. 2-Phenyl-4-quinolinecarboxylic acid has shown the ability to inhibit leukemia inhibitory factor (LIF) production by lymphocytes, which may have a role in the development of leukemia. This drug also possesses antioxidative properties and has been shown to have high values in group P2 polymerase chain reactions.

2,2'-Biquinoline-4,4'-dicarboxylic acid is a naturally occurring molecule that has been shown to have potent antimicrobial activity against Gram-positive and Gram-negative bacteria. It interacts with the protein in the cell membrane and blocks iron uptake by the bacteria, which causes oxidative stress and leads to cell death. The compound also inhibits DNA synthesis by binding to the enzyme polymerase chain reaction (PCR). This binding prevents DNA replication and transcription. 2,2'-Biquinoline-4,4'-dicarboxylic acid has been shown to have antiviral properties in vitro. It also binds to human serum proteins through a covalent bond and can be detected using fluorescence probe methods or plasma mass spectrometry.

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3-Chloro-1H-indole-2-carbaldehyde is a bifunctional reagent that can be used to form amides. It reacts with primary and secondary amines, as well as dialkyl and methylene amines, to produce the corresponding chloro-, phenylhydrazine-, or nitrosoaminoureas. This reaction is intramolecular and yields the desired product in high yield. The reactant can also be used as a chloride source. 3-Chloro-1H-indole-2-carbaldehyde is manufactured by reacting phenylhydrazine with chloroacetic acid in an organic solvent at room temperature (25°C).

Applications Pyridoxamine Dihydrochloride (cas# 524-36-7) is a compound useful in organic synthesis.

Applications 2-azaspiro[4.5]decane-1,3-dione (cas# 1197-80-4) is related to gabapentin (G117250).

Please enquire for more information about 5-Bromoquinolin-6-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Acetyl-1H-indazole-6-boronic acid, pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

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5-fluoro-2,2-dimethyl-indoline is an amide that acts as a cyclic ether. The compound has been shown to be orally bioavailable and is active against Gram-positive bacteria. It is also a lead compound for the development of new antibiotics. 5-fluoro-2,2-dimethyl-indoline targets the active site of bacterial enzymes and inhibits them by binding to their amino acid residues. This binding prevents the enzyme from functioning correctly and leads to cell death. 5-fluoro-2,2-dimethyl-indoline works by inhibiting class A β lactamases which are found in Gram negative bacteria and some Gram positive bacteria such as Clostridium difficile. It also inhibits peptidoglycan synthesis by binding to the peptidyl transferase or ribosome, which prevents protein synthesis.

Please enquire for more information about Methyl 3-Formyl-6-Methoxy-1H-Indole-2-Carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

A building block; used for synthesis tryptophan 2,?3-?dioxygenase inhibitors

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3-Bromo-4-Nitro-1H-Indole is an indole that contains a 6 membered ring. It is an analogue of the natural product isatin, which is found in the bark of the Isatis tinctoria plant. 3-Bromo-4-Nitro-1H-Indole can be brominated to form 3,4-dibromoindole.

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Applications 2-Chloroquinolin-6-ol can be used for hair dye compositions. References Lagrange, A., et.al., PCT Int. Appl., 87, (2012);

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tert-Butyl 3-formyl-1H-indole-1-carboxylate is a cyclopropane compound that can be synthesized by cyclodehydration of tert-butyl 3-formylindole-1,3-dicarboxylate. This chemical is homochiral and has a tetrahydrofuran ring. The tertiary amide group makes this compound nucleophilic and able to react with azides. It can also react with enantiomerically pure benzyl azide, which yields the corresponding indole nitrogen. The yield for this reaction is about 86%.

Cis-dithiocyanatobis(N,N'-2,2'-bipyridyl-4,4'-dicarboxylic acid)ruthenium is a hydrogen fluoride (HF)-stable and light-sensitive dye that can be used in solar cells. It has been shown to be stable under illumination in the presence of water and to generate a photocurrent. This dye has also been shown to have a low energy optical absorption band with a broad absorption spectrum that ranges from UV to visible light. Cis-dithiocyanatobis(N,N'-2,2'-bipyridyl-4,4'-dicarboxylic acid)ruthenium is a redox dye that undergoes oxidation and reduction reactions to produce an electron transfer between the dye molecule and the electrode. This electron transfer is enhanced by hydrogen bonding interactions between the dye molecule and the polymer film.

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2-(2-Chloroethyl)-1H-isoindole-1,3(2H)-dione is a colorless solid that is soluble in organic solvents. It is used as a reagent to synthesize other organic compounds and as an analytical reference material. The molecular geometry of 2-(2-Chloroethyl)-1H-isoindole-1,3(2H)-dione has been determined by microcalorimetry and found to be linear with a C=C double bond. This compound can be analyzed by calorimetry to determine enthalpic and entropic contributions to the free energy of formation. The enthalpy change for the reaction is -23.4 kcal/mol, while the entropy change is -8.5 cal/(molK).

7-Chloropyrido[4,3-b]pyrazine is a potent inhibitor of protein kinases that belongs to the group of disubstituted pyridines. It has shown to be an efficient inhibitor of tyrosine and serine/threonine protein kinases with a potency comparable to that of staurosporine. 7-Chloropyrido[4,3-b]pyrazine is being studied as a drug discovery tool for the optimization of protein kinase inhibitors.

Please enquire for more information about {3-[2-(8-Methoxy-1,2,3,4-tetrahydroquinolin-2-yl)ethyl]phenyl}amine dihydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

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2,3-Dihydro-1H-cyclopenta[b]quinolin-9-amine is a quinoline derivative that inhibits the activity of tyrosine kinases. It binds to the active site of the enzyme and prevents it from binding to its substrate, thus inhibiting its activity. 2,3-Dihydro-1H-cyclopenta[b]quinolin-9-amine has been shown to inhibit the tyrosine kinase EGFR with an IC50 value of 0.5 μM in vitro. This drug has also been shown to be effective against other tyrosine kinases such as Src and PDGFRβ.

2-(2-Aminophenyl)-1H-isoindole-1,3(2H)-dione is a fluorescent substrate for kinetics. It has been shown to be a good kinetic probe for catalysed reactions. The fluorescence of 2-(2-Aminophenyl)-1H-isoindole-1,3(2H)-dione is enhanced in the presence of hydrogen bonding interactions. This reaction is also anomalously sensitive to parameters such as temperature and solvent composition. Intermolecular hydrogen bonding has been shown to play an important role in the hydrolysis reaction of 2-(2-Aminophenyl)-1H-isoindole-1,3(2H)-dione. The substrate binds to benzene rings through polyhydroxy groups, forming a covalent bond with the aromatic ring.

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Neobyakangelicol is a phytochemical compound, which is a natural product derived from various plant species. Its source is predominantly the roots of certain medicinal plants that are known for their array of bioactive constituents. The mode of action of Neobyakangelicol primarily involves interacting with specific biochemical pathways, potentially including modulation of enzyme activity or receptor binding, which could result in diverse pharmacological effects. The uses and applications of Neobyakangelicol are mainly centered around its potential therapeutic benefits. It has been the subject of research studies exploring its effects in various biological systems, often with a focus on its antioxidant, anti-inflammatory, or other modulatory roles within cellular processes. As such, it is a compound of interest in the field of drug discovery and development, particularly in the quest for new treatments for diseases that involve oxidative stress and inflammation. Additionally, its natural origin as a phytochemical adds a layer of interest for those investigating plant-derived compounds with possible health benefits.

5,12-Dibutylquinacridone is an electron acceptor that is used as a monomer in cationic polymerization. It can be polymerized with acrylates to form polymers that have high fluorescence and photopolymerizable properties. 5,12-Dibutylquinacridone has shown to be reactive with epoxides and diene compounds, which are typically used as monomers in the synthesis of polymers. This chemical has been studied for its use in solar cells and photocurrent generation. The electron spin resonance technique has been used to study the chemical's photophysical properties.

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4'-(4-Methylphenyl)-2,2':6',2''-terpyridine (TPEN) is a chemical compound with anti-cancer properties that has been shown to induce apoptosis in cancer cells. TPEN also inhibits the growth of tumor cells by interacting with mitochondria and inducing mitochondrial dysfunction. TPEN synergistically induces death in neuronal cells when combined with other agents that are known to cause neuronal cell death. In vivo studies have shown that TPEN produces neuroprotective effects at normoxic temperatures, but can be toxic at hyperthermic temperatures.

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Indole-3-glyoxylic acid is a molecule that contains a hydroxyl group, a chloride, an indole carboxylate and an amide. It is found in mammalian cells and has been shown to inhibit the production of platelets by blocking the metabolism of arachidonic acid. Indole-3-glyoxylic acid also has anticancer activity, as it inhibits protein synthesis and cell division. This molecule is also involved in plant physiology, as it stimulates ascidian egg production in the presence of sodium succinate and carbon source. The optimum pH for this reaction is 7.0. Indole-3-glyoxylic acid will react with wild type strains of Escherichia coli to form indoxyl sulphate and glycerol phosphate, which are products of its metabolic breakdown.

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