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Please enquire for more information about 7-[(Dimethylamino)methyl]-2,2,4-trimethyl-1,2,3,4-tetrahydroquinolin-6-ol including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2,7-Dimethyl-1-propyl-1H-indole-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Bromo-2-(4-bromophenyl)-indole is a fine chemical with CAS No. 28718-96-9 that can be used as a versatile building block for the synthesis of complex compounds, useful scaffold for research chemicals, and reaction component for speciality chemicals. This compound has high quality and is a reagent in the synthesis of other compounds.

5-Methylindole-3-acetic acid (5MI3A) is a molecule that has been shown to have antiproliferative properties in bladder cancer cells. 5MI3A binds to the receptor for GABA, which is an inhibitory neurotransmitter. It also inhibits the production of proinflammatory mediators and reactive oxygen species in cancer cells. 5MI3A has anticancer activity in prostate cancer cells and may act by inducing apoptosis and inhibiting cell proliferation. Consumption of 5MI3A may reduce the risk of cancer development by preventing DNA damage from carcinogens, suppressing inflammation, and regulating cell growth through its antagonistic properties.

Please enquire for more information about 2-(4-Chlorophenyl)-6,8-dimethylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-(Phenylsulfinyl)-1H-indole-2-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Chloro-6-methyl-1H-indole is a potential drug that acts as an allosteric modulator of the GABA receptor. 5-Chloro-6-methyl-1H-indole has been shown to increase the affinity of the sensor domain for GABA, which increases the sensitivity of the sensor domain to GABA and can reduce the frequency of spontaneous opening. 5-Chloro-6-methyl-1H-indole has also been shown to bind to allosteric sites on the GABA receptor and alter its function. It has been shown to be a potent antagonist of recombinant human α4β2 receptors with an IC50 value of 1 μM. The efficacy of this compound was tested in rat cortical neurons and its effects were confirmed by measuring changes in intracellular calcium levels.

Applications Oxyquinoline Sulfate is used as a food preservative. References Gendy, A. et al.: Aud. J. Basic. App. Sci., 6, 260 (2012); Abou El-Ghait, E. et al.: Res. J. Agri. Biol. Sci., 8, 261 (2012);

Please enquire for more information about 8-[(2-Furylmethyl)thio]-5-nitroquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-(4-Methylphenyl)-1,2,3,4-tetrahydrocyclopent[b]indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(4-Ethoxyphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Diuretic; cardiac stimulant; smooth muscle relaxant; bronchodilator

Please enquire for more information about 1-(4-Methylbenzyl)-1H-indole-6-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-[3-[3-[(1E)-2-(7-Chloro-2-quinolinyl)ethenyl]phenyl]-3-oxopropyl]benzoic acid methyl ester is a five-membered ring compound. It has organic solvents that can be screened for biological activity using high throughput screening. This compound is insoluble in water and reacts with bases, acids, and other compounds to form salts, benzoates, or crystallizing solids. The molecular conformation of this compound was determined by bioinformatics methods. It is a member of the class of 7-chloroquinoline derivatives that have been shown to inhibit Singulair (montelukast), an asthma drug. These agents are thought to bind to the active site of the enzyme cytochrome P450 and may also inhibit its ability to metabolize drugs such as acetaminophen and phenytoin.

Please enquire for more information about N-Benzyl-isoindoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

4,5-Dimethoxyindole is a chemical compound that has been shown to exhibit radical scavenging activity. It is an inhibitor of integrase, which are enzymes involved in the integration of viral DNA into host cell chromosomes. This compound has been synthesized and its optical properties have been studied. The synthesis of 4,5-dimethoxyindole derivatives has also been investigated using molecular modeling. Schrodinger software was used to predict the geometry of these synthesized derivatives. These studies suggest that 4,5-dimethoxyindole may be a potential anti-cancer agent due to its ability to inhibit cancer cell growth and induce apoptosis.

Applications 3,4-Dihydroisoquinoline-6,7-diol acts as a reagent for the synthesis of 6,7-dihydroxy-3,4-dihydroisoquinline, a novel inhibitor factore-kB in invitro invasion in murine mammary cells. References Alvarez, F. N., et al.: Chemotherapy, 55, 175 (2009)

8-Methoxy-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is a versatile building block that can be used as a reagent or speciality chemical. It has been used in research and development of pharmaceuticals and as a useful intermediate for the synthesis of other compounds. 8-Methoxy-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole is an important reaction component for the synthesis of many types of compounds such as indoles, coumarins, and quinazolinones.

Please enquire for more information about 6-Ethyl-2-(5-ethyl-2-thienyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-(4-Fluorophenyl)pyrazolo[1,5-a]pyrimidine-7-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Bromoisoquinolin-3(2H)-imine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 7-Fluoro-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Isatin bis-cresol is a silicon-containing compound that can be used as a viscosity modifier and stabilizer in polymers. Isatin bis-cresol has shown resistance to degradation by water, alkali, and acid. It also has a high formation rate and can be used for the production of functionalized polymers such as polycarbonates or phosphonium salts. Isatin bis-cresol is insoluble in water but soluble in organic solvents, which makes it an ideal candidate for use in transesterification reactions. Isatin bis-cresol contains three functional groups: phenolic (OH), carboxylic acid (COOH), and alcohol (OH).

Applications 2-(2-OXO-1,2,3,4-TETRAHYDROQUINOLIN-3-YL)ACETIC ACID (cas# 61164-71-4) is a useful research chemical.

Please enquire for more information about 2-Chloroquinoline-6-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Hydroxy-1-oxo-1,2-dihydroisoquinoline-3-carbohydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Cyclopropyl-6-methylquinoline-4-carbohydrazide including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Methyl-1H-indole-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Chloro-2-(4-isobutylphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5,6-Difluoro-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Methyl-1H-indazole-6-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Applications 6-Chloro-7-deazapurine Hydrochloride (cas# 1243346-92-0) is a compound useful in organic synthesis.

Phenanthridin-6(5H)-one is a chemical compound that has been shown to have pharmacokinetic properties in an experimental model. The sample preparation for the experiment was conducted using palladium-catalyzed coupling of phenanthridone with sodium carbonate. Phenanthridin-6(5H)-one demonstrated genotoxic activity by causing neuronal death in rats exposed to radiation or x-rays. The results of this study suggest that phenanthridon-6(5H)-one may be a potential therapeutic agent for treatment of cancer and neurological disorders.

Ethyl 7-bromo-4-chloroquinoline-3-carboxylate is an optimal inhibitor of protein kinase. It has been shown to inhibit the activity of both tyrosine and serine/threonine protein kinases. The compound inhibits the coupling of ATP to its natural substrate, which leads to inhibition of cellular activity. This product also inhibits enzymatic activity, specifically through the ethynyl group. The methoxy group prevents the binding of substrate and ATP, leading to a decrease in cellular activity.

Please enquire for more information about 1-Ethyl-2,6-dimethyl-1H-indole-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Cyclohexyl-1-[4-[2-(7-methoxy -4,4-dimethyl-1,3-dioxo-isoquinolin -2-yl)ethyl]phenyl]sulfonyl-urea is a drug that inhibits the enzyme DPPIV, which breaks down the incretin hormone glucagon-like peptide (GLP)-1. It may be used to treat diabetes by regulating blood glucose levels. This drug has been shown to reduce postprandial blood glucose levels in patients with type 2 diabetes. 3CYCSU is also capable of reducing body weight and food intake in mice. The mechanism of action of this drug is not fully understood, but it appears to have an effect on the cytosolic calcium ion concentration and may reduce inflammatory responses in cells. 3CYCSU is a promising potential treatment for infectious diseases such as Hepatitis C virus (HCV).

Please enquire for more information about N-[(1-Propyl-1,2,3,4-tetrahydroquinolin-6-yl)methyl]cyclopentanamine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Methyl4-hydroxy-6-methylquinoline-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-[2-(2,5-Dimethyl-1H-pyrrol-1-yl)ethyl]-1H-indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Vaginidin including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Methyl-2-(4-methylphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(2,5-Dimethoxyphenyl)-8-methylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Ethoxy-1-propyl-1H-indole-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(2-Chlorophenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Methyl indoline-4-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

3-Hydroxycoumarin is a coumarin derivative, which is a type of organic compound with significant pharmacological interest. It is derived from the parent structure of coumarin, naturally found in various plant sources such as tonka beans and sweet clover. Its molecular structure includes a hydroxyl group added at the third position of the coumarin backbone, conferring distinct chemical properties. The mode of action of 3-Hydroxycoumarin is primarily attributed to its interaction with biological macromolecules, enabling it to inhibit enzymes and interfere with cellular processes. This compound is known for its ability to act as an anticoagulant by inhibiting vitamin K-dependent synthesis of clotting factors, similar to warfarin. 3-Hydroxycoumarin has various applications, particularly in the field of medicinal chemistry, where it is explored for its potential therapeutic effects. It serves as a pivotal scaffold in the development of anticoagulant drugs and has been investigated for its antioxidant, antimicrobial, and anticancer properties. Its diverse biological activities make it a subject of ongoing research, with potential applications extending to drug development and biochemical studies.

Please enquire for more information about 2-(4,4-Diethoxybutyl)-1H-isoindole-1,3 (2H)-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6-Bromo-2-pyridin-3-ylquinoline-4-carbonyl chloride hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Methyl 5-bromo-6-chloro-1H-indazole-4-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Methoxy-9H-purine is an analog of adenosine and has been shown to have anticancer activity in vivo. It inhibits the growth of virus by binding to the viral DNA polymerase, thereby inhibiting viral replication. 6-Methoxy-9H-purine has also been shown to be active against cancer cells that are resistant to other anticancer agents, such as herpes simplex virus. The drug is currently undergoing toxicity studies in rats and dogs. 6-Methoxy-9H-purine can be administered orally or by intravitreal injection. Intravitreal injection is a method where the drug is injected into the eye through a needle. This route of administration may reduce systemic toxicity because it leaves less drug in the bloodstream.

Please enquire for more information about 3-Amino-6-methoxy-1H-indole-2-carbohydrazide hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Methyl-5-nitroisoquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-Methyl-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indole hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Bromo-7-chloroisoquinolin-1(2H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Indoline-6-carboxylic acid hydrochloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Ethyl 4-chloro-8-methoxyquinoline-3-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

8-Chloro-2-(2-furyl)quinoline-4-carboxylic acid (8CQCA) is a coumarin derivative that is used as an inhibitor of the RNA polymerase. It binds to the active site of the enzyme, blocking the synthesis of RNA. 8CQCA has been shown to inhibit mitochondrial DNA polymerase and increase sensitivity to cisplatin in cancer cells. 8CQCA has also been shown to inhibit polymerases involved in DNA replication, such as DNA and RNA polymerases, and this inhibition can lead to cell death by inhibiting the production of proteins vital for cell division.

Please enquire for more information about 10-Amino-1,2,3,4,5,6,7,8-octahydrophenanthrene-9-carbonitrile including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(3-Aminophenyl)-6-methylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Nitroindole is a heterocyclic compound that belongs to the group of nitro compounds. It is a methylating agent that can be used for the production of 6-nitropurines, which are used as anticancer agents. The reaction mechanism of this compound involves the attack of the electrophilic nitro group on an electron-deficient carbon atom in a molecule. This process creates an N-methylated product, which can then be oxidized to form a carboxylic acid. The kinetics of this reaction have been studied using kinetic data and anomers. 6-Nitroindole has also been shown to inhibit DNA synthesis by binding to oligodeoxynucleotides and inhibiting their catalytic activity.

Please enquire for more information about (2R,3R)-2,3-Difluoro-1,4-Diazabicyclo[2.2.2]Octane including the price, delivery time and more detailed product information at the technical inquiry form on this page

Indole-5-carboxylic acid ethyl ester is a formamide activated analog of piperidine. It is an effective antibacterial agent against Staphylococcus aureus. Indole-5-carboxylic acid ethyl ester inhibits the growth of bacteria by binding to the extracellular surface and interfering with cell membrane permeability. The compound also has anti-cancer properties, and may be used in pharmaceuticals as a pyrazole derivative.

Please enquire for more information about 4-Chloro-5-fluoro-7-azaindole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Quinolinium is a molecule that contains a quinoline ring. Quinolinium itself is an inactive molecule, but it can be activated by removing one of the hydrogen molecules. The activation energy for this reaction is low, and the reaction proceeds spontaneously at room temperature. Quinolinium may also be activated by removing a chloride ion or metal ion to form 5-(chloromethyl)quinolin-8-ol hydrochloride (5CQ). This compound has potentiodynamic polarization properties that allow it to be used as a reagent in organic synthesis. 5CQ can also be used as an adsorbent in ion-exchange chromatography due to its ability to bind positively charged ions such as sodium and potassium ions.

Please enquire for more information about 9-(5-Methyl-2,3,5-tri-O-benzoyl-beta-D-ribofuranosyl)-6-chloropurine including the price, delivery time and more detailed product information at the technical inquiry form on this page