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Please enquire for more information about 8-Bromo-7-chloroquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Azaspiro[2.4]heptane is an alkene that has been synthesized and optimized to produce a cyclopropene with the desired mechanistic and stereoselective properties. The synthesis of 5-azaspiro[2.4]heptane was achieved by ring-opening a variety of piperidines with 1,1'-azodicarbonyl diimidazole. This compound has shown pharmacokinetic properties in rodents similar to those of azetidine, but it is less toxic than azetidine. 5-Azaspiro[2.4]heptane also inhibits the activity of azetidines, which are enzymes that catalyze three consecutive steps in the biosynthesis of heme, including the conversion of aspartate to 2-oxoglutarate and the conversion of succinyl CoA to succinate.

Please enquire for more information about 4-{[(6,8-Dimethyl-2,3-dihydro-1H-pyrido[2,3-b][1,4]thiazin-1-yl)carbonyl]amino}benzoic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Methyl-2H-indazole-6-boronic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 4-Chloro-6-methylquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-(3,5-Dichloro-4-methoxyanilino)-6-methoxy-7-[3-(4-methylpiperazin-1-yl)propoxy]Quinoline-3-carbonitrile is a hydrogen ion pump inhibitor that has been shown to provide relief from congestive heart failure and hyperproliferative diseases. It inhibits the action of the sodium/hydrogen ion exchanger in the cell membrane, preventing the movement of sodium ions into and out of cells. The compound is biocompatible with human albumin, which may allow it to be used as a drug delivery system for cancer treatments. The molecule also functions as an efficient diode when placed in water vapor, which may be useful for detecting water leaks or monitoring humidity levels.

Please enquire for more information about 1-(2-Bromo-4,5-dimethoxybenzyl)-6,7-dimethoxyisoquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Rac1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid is a potent inhibitor of the Mcl-1 protein. Rac1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid has been shown to inhibit locomotor activity and to have potent inhibitory activity against bacteria. Rac1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid inhibits the antimicrobial peptide LL37 by binding to its active site and prevents LL37 from binding to bacterial cells. Rac1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid also inhibits chloride ion transport in mammalian cells. This compound has low expression in mammalian cells and erythrocytes. It is not toxic to these cells as it does not bind to plasma glucose or proteins in vitro. Rac1

2-Aminoquinoline-3-carboxamide is a chemical compound with the molecular formula CHNO. It has an alkoxide group, which is a functional group consisting of one oxygen atom attached to two hydrocarbon groups. This alkoxide reacts with potassium and alkoxides to form salts, such as potassium 2-aminoquinoline-3-carboxylate. The pyrimidine ring in this molecule can be oxidized by sodamide and carboxamide to form pyrimido derivatives. Hydride reduction of these compounds produces cyclization products. In addition, it reacts with antiallergic drugs (e.g., hydrocortisone) to produce their corresponding quinolones in nuclear reactions.

3-[2-[4-(4-Fluorobenzoyl)-1-oxidopiperidin-1-yl]ethyl]-2,7-dimethylpyrido[2,1-b]pyrimidin-4-one (7FPP) is a polyfunctional molecule that exhibits anions and cations. It is a reactive compound and has been characterized by laser spectroscopy and microprobe analysis. 7FPP has been shown to be an effective scavenger of oxygenated molecules such as peroxides, hydroperoxides, and peroxyacids. 7FPP also has the ability to desorb cations from surfaces such as aluminum oxide and silicon dioxide. Rationally designing 7FPP with different functionalities will allow for the optimization of its properties.

Tricyclohexylphosphine is a compound that is used in organic synthesis to form stable complexes with reactive functional groups such as trifluoroacetic acid, glycol ethers, and sodium carbonate. The reaction solution of these compounds forms a complex with copper chloride and fluorescence probe, which can be analyzed by x-ray crystallography. The reaction mechanism of this compound involves coordination geometry and hydroxyl group. Its basic structure is a trivalent phosphorus atom coordinated to three ligands. Structural analysis of this compound has been done using kinetic data and the results have indicated that the reaction proceeds through an SN2-like mechanism.

Please enquire for more information about 6-Cyano-2-(4-cyanophenyl)indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-Amino-4-bromo-5-phenylpyrazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Hydroxyquinoline-(1H)-2-one is an organic compound that has been shown to inhibit the uptake of carbostyril by bacterial cells. This inhibition causes increased uptake of xanthurenic acid and anthranilic acid, which are two compounds that are found in wastewater treatment. 6-Hydroxyquinoline-(1H)-2-one may be a potential anticancer agent, as it inhibits the growth of astroglia cells and bladder cancer cells. It also reacts with acylation reactions to form quinolinic acid, which has been shown to have anticancer effects.

Please enquire for more information about 2-(Chloroacetyl)-8-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(4-Ethoxyphenyl)-8-methylquinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

4-Chloro-6-methoxyquinolin-7-ol (CMQ) is an alkali metal that inhibits the sodium/potassium ATPase pump, which is responsible for maintaining the cell's intracellular ion balance. It was discovered in a search for compounds that inhibit this enzyme and show promise in the treatment of heart diseases. CMQ has been shown to inhibit the sodium concentration in rat hearts with no effect on potassium concentrations, which may be due to its ability to bind to sodium ions but not potassium ions. The long-term effects of CMQ on human populations are unknown, as well as its effects on genotype and parameters. CMQ also has been shown to cause drug resistance mutations in bacteria, such as methicillin resistant Staphylococcus aureus (MRSA), by increasing the mutation rate. This is due to the fact that it inhibits DNA replication and protein synthesis in bacteria cells.

Please enquire for more information about 2-Butyl-1'-methyl-1-oxo-1,4-dihydro-2H-spiro[isoquinoline-3,4'-piperidine]-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Trichloromethylazacycloheptane is a synthetic compound that has been shown to be effective in the treatment of chronic pain. It is also used as an antiglaucoma drug and to treat endometriosis. Trichloromethylazacycloheptane has been prepared by reacting malonic acid with hexane in the presence of colitis, which is a type of bowel inflammation. The chloride ion acts as a nucleophile and attacks the electron-deficient carbon atom, forming a chloroformate intermediate. This intermediate reacts with chloride ion to form 2R,5S)-2-trichloromethyl-3-oxa-1-azabicyclo[3,3,0]octane-4-one.

Please enquire for more information about 5-Iodo-1H-indazole including the price, delivery time and more detailed product information at the technical inquiry form on this page

Murralongin is a natural compound that falls under the category of sesquiterpenes, a class of terpenoids characterized by their three isoprene units. It is derived from the leaves and stems of the plant Eremophila mitchellii, a species known for its rich diversity of bioactive compounds often utilized in traditional medicine. The primary mode of action of Murralongin involves modulation of specific enzymatic pathways, potentially influencing a range of biological processes, including anti-inflammatory and antimicrobial activities. Recent studies have focused on its potential therapeutic uses, exploring its efficacy as an anti-cancer agent by targeting cellular pathways involved in cancer cell proliferation and survival. Additionally, Murralongin's ability to inhibit certain microbial growth suggests applications in developing new antimicrobial drugs, addressing issues related to resistant bacterial strains. Furthermore, its anti-inflammatory properties imply potential applications in managing chronic inflammatory conditions, where current treatments may have significant limitations or side effects. Overall, Murralongin represents a promising subject for further research with the potential to contribute significantly to the development of new therapeutic agents.

Applications Quinoline-4-carboxylic acid (cas# 486-74-8) is a useful research chemical.

Please enquire for more information about Heratomol including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Amino-6-(methylamino)quinoline is a molecule that inhibits the enzymatic activity of tyrosine phosphatases and has been shown to inhibit the growth of typhimurium ta98, which is resistant to quinoxaline. It has also been shown to be mutagenic in vitro. 5-Amino-6-(methylamino)quinoline has an imidazole ring and is synthesized from 2-methylbenzothiazole and N,N'-dimethylethylenediamine. The synthesis of this compound takes place in two steps with the first step being an oxidative cyclization followed by a reductive amination.

Please enquire for more information about 7-Methoxy-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole including the price, delivery time and more detailed product information at the technical inquiry form on this page

9-Hexahydro-9-Xanthene-9-Carbohydrazide is an herbicide that inhibits the growth of dicotyledons. It has been shown to have a substituent effect on phenyl. 9HXCZ binds to the active site of the enzyme, which prevents it from catalyzing reactions that would otherwise result in the synthesis of acetyl coenzyme A (acetyl CoA). 9HXCZ also inhibits the production of glucose by inhibiting the enzyme phosphoglucomutase.

Please enquire for more information about 2-(5-Chlorothien-2-yl)-6-methylquinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 3-(1,1-Dioxido-2H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1-methyl-2(1H)-quinolinone including the price, delivery time and more detailed product information at the technical inquiry form on this page

2-Hydroxyamino-3-methyl-3H-imidazo[4,5-f]quinoline (2HAIQ) is a reactive compound that binds to DNA. It has been shown to be a potent inhibitor of the enzyme cytosolic protein kinase C, which plays an important role in regulating cellular metabolism. 2HAIQ also inhibits the activity of enzymes such as hydroxylases and polymerases. The binding of 2HAIQ to DNA is thought to inhibit transcription by preventing RNA polymerase from transcribing DNA. 2HAIQ may also inhibit replication by binding to the dinucleotide phosphate molecule, which is essential for DNA synthesis.

2,4-Dihydroxy-6-methoxyquinoline is a compound that exhibits antifungal properties. It has been shown to have activity against Aspergillus flavus, Aspergillus fumigatus, Candida albicans and other fungi. 2,4-Dihydroxy-6-methoxyquinoline also inhibits the growth of E. coli and A. aureus in vitro. Elemental analysis showed that this compound possesses antibacterial properties and can inhibit the growth of Staphylococcus aureus.

Please enquire for more information about 5-Bromo-4,4-dimethyl-1,2,3,4-tetrahydroisoquinoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-(2-Ethoxyphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 1-[Chloro(phenyl)acetyl]indoline including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Benzyl 2,4-dichloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Oxindole-4-boronic acid, pinacol ester including the price, delivery time and more detailed product information at the technical inquiry form on this page

7-Bromoindoline is a tricyclic compound that belongs to the class of natural products. It has been used as a lead compound for drug discovery and is synthesized from an aryl halide and palladium. 7-Bromoindoline has been shown to be active against methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis, with the latter being attributed to its ability to inhibit protein synthesis by binding to bacterial RNA polymerase. 7-Bromoindoline also exhibits anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis.

Please enquire for more information about 3-(3,4-Dihydroisoquinolin-2(1H)-yl)propan-1-amine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Oroselol is an innovative beta-adrenergic blocker, which is a synthetic derivative with unique cardiovascular targeting properties. It is sourced from engineered chemical synthesis, utilizing advanced molecular design to enhance selectivity for beta-adrenergic receptors. The mode of action of Oroselol involves competitive antagonism of beta-1 and beta-2 adrenergic receptors, leading to a decrease in heart rate and myocardial contractility. This blockade of adrenergic stimulation results in reduced cardiac output and lower blood pressure. The primary uses of Oroselol lie in its potential applications for managing cardiovascular conditions such as hypertension, angina pectoris, and arrhythmias. Its precise receptor selectivity may offer a therapeutic advantage over traditional beta-blockers by minimizing side effects associated with non-targeted action. Oroselol's pharmacokinetics and dynamic properties are being closely studied to understand its efficacy and safety profile in clinical settings. This compound's novel aspects make it a subject of considerable interest in pharmacological research, where its impact on cardiovascular therapy continues to be evaluated.

Please enquire for more information about Ethyl 5-chloro-1,3-dimethyl-1H-indole-2-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Pyridin-4-yl-1H-indole-3-carbaldehyde including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 8-(Bromoacetyl)quinoline HBr including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Methyl 6-amino-3,4-dihydroquinoline-1(2H)-carboxylate including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Bromo-1-methyl-1H-indole-3-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 6,8-Dimethyl-2-(4-propoxyphenyl)quinoline-4-carbonyl chloride including the price, delivery time and more detailed product information at the technical inquiry form on this page

L-(2S,3aR,7aS)-Octahydroindole-2-carboxylic acid is an opioid drug that binds to the μ-opioid receptor. It is a synthetic compound with affinity for the opiate receptors in the brain and spinal cord, which leads to its analgesic effects. L-(2S,3aR,7aS)-Octahydroindole-2-carboxylic acid has been industrially produced by cyclizing the dimethyl ester of L-tryptophan. This synthesis process can be carried out by refluxing 3-hydroxy indole with acetic anhydride and hydrochloric acid in methanol at 60°C for about 16 hours. The resulting product is then heated with concentrated hydrochloric acid until it crystallizes. The resulting product can then be recrystallized from hot water or ethanol and dried over magnesium sulphate. L-(

Trans-Khellactone is a naturally occurring lactone derivative, which is isolated from plants of the Apiaceae family. This compound exhibits a variety of biological functions due to its unique chemical structure, which includes a dihydropyran ring. Trans-Khellactone's mode of action involves interacting with various cellular pathways, potentially modulating enzyme activity, receptor binding, and influencing signal transduction processes. Due to its diverse range of activities, trans-Khellactone is of significant interest in the field of medicinal chemistry. It has been studied for its potential therapeutic applications, including anti-inflammatory, anti-cancer, and anti-microbial effects. Research into trans-Khellactone's mechanisms and efficacy continues to expand its possible applications in drug development and other areas of biomedical research.

7-Fluorooxindole is an alkylating agent that can be used in the synthesis of oxindoles. This compound can be prepared by aldol condensation reaction with butyllithium, followed by alkylation with bromides or iodides. The use of 7-fluorooxindole and its derivatives has been optimized to yield high yields. The optimal conditions for this reaction are deprotonation with an organometallic reagent, such as butyllithium, followed by alkylation with bromides or iodides.

Please enquire for more information about 6,8-Dimethyl-2-(2-methylphenyl)quinoline-4-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 5-Amino-3,7-dimethylxanthine including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about 2-Ethoxy-7,7-dimethyl-10-thioxo-7,10-dihydro[1,2]dithiolo[3,4-c]pyrrolo[3,2,1-ij]quinoline-4,5-dione including the price, delivery time and more detailed product information at the technical inquiry form on this page

Lactone

Please enquire for more information about 2'-Cyclohexyl-1'-oxo-1',4'-dihydro-2'H-spiro[cyclopentane-1,3'-isoquinoline]-4'-carboxylic acid including the price, delivery time and more detailed product information at the technical inquiry form on this page

Xanthoxyletin is a coumarin, which is a type of natural organic compound commonly found in plants, particularly in the Rutaceae family. It is sourced from various plant species, including Zanthoxylum, known for their ethnobotanical uses. Xanthoxyletin functions primarily through its biochemical activity, including the inhibition of certain enzymes and modulation of cellular pathways that influence its pharmacological effects. This compound exhibits a wide range of biological properties, including antibacterial, antifungal, anti-inflammatory, and antiproliferative activities. Due to these properties, xanthoxyletin is of great interest in the field of medicinal chemistry and pharmacology. It is studied for its potential therapeutic applications, particularly in the development of new treatments for infectious diseases and inflammatory conditions. Research also explores its role in cancer research, where it may contribute to the development of novel chemotherapeutic agents. Scientists are continually exploring its bioactivity and possible synergistic effects with other compounds to enhance its efficacy and broaden its application scope.

Please enquire for more information about 3-Chloro-4-hydroxy-1-methylquinolin-2(1H)-one including the price, delivery time and more detailed product information at the technical inquiry form on this page

Please enquire for more information about Peuarin including the price, delivery time and more detailed product information at the technical inquiry form on this page

5-Fluoroquinoline is a quinoline derivative that has been shown to have tumorigenic activity in animal bioassays. In addition, 5-fluoroquinoline induced genotoxic effects in liver cells and was found to be carcinogenic in rats and mice. The mechanism of action of 5-fluoroquinoline is not yet known, but it is thought to be due to its ability to bind covalently with DNA. It also binds to RNA and protein in the cell, which may lead to inhibition of transcription or translation.

Please enquire for more information about 4-Ethyl-1,2,3,4-tetrahydropyrido[2,3-b]pyrazine including the price, delivery time and more detailed product information at the technical inquiry form on this page

6-Aza-5-methyl-1H-indazole is a chemical compound that acts as a building block for the synthesis of pharmaceuticals and other compounds. It is used in research for the development of new drugs, such as antihypertensive agents, antibiotics, and immunosuppressants. 6-Aza-5-methyl-1H-indazole has been shown to be an effective intermediate in the synthesis of many complex compounds, including cephalosporins, penicillins, carbapenems, and aminoglycosides. This versatile reagent can be used to synthesize a wide variety of organic compounds.

6-Bromo-1-chloroisoquinoline is a chemical compound that belongs to the group of disulfides. It is an optical isomer of 6-bromo-1-chloroisoquinoline, which is used as a starting material for the synthesis of other compounds. The synthesis of 6-bromo-1-chloroisoquinoline from acetonitrile and phosphorus oxychloride can be achieved using a Grignard reagent with an xanthate and halides. This reaction produces alkyl chlorides, which can be converted in turn into sulfones or sulfoxides. This compound has been shown to react with sodium sulfide and carbon disulphide to form the corresponding disulfide. 6-Bromo-1-chloroisoquinoline has also been shown to react with phosphine and sulfide to form polysulphides.

Please enquire for more information about 9-(2’-O-Acetyl-5’-O-benzoyl-3’-O-methyl-beta-D-ribofuranosyl)-6-chloropurine including the price, delivery time and more detailed product information at the technical inquiry form on this page